Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Fabien Campagne"'
Autor:
Guillaume Hanouna, Laurent Mesnard, Sophie Vandermeersch, Joëlle Perez, Sandrine Placier, Jean-Philippe Haymann, Fabien Campagne, Julien Moroch, Aurélien Bataille, Laurent Baud, Emmanuel Letavernier
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Calpains are ubiquitous pro-inflammatory proteases, whose activity is controlled by calpastatin, their specific inhibitor. Transgenic mice over-expressing rabbit calpastatin (CalpTG) are protected against vascular remodelling and angiotensin
Externí odkaz:
https://doaj.org/article/f3860defad88411f8f61a846a295deea
Autor:
Laurent Mesnard, Thangamani Muthukumar, Maren Burbach, Carol Li, Huimin Shang, Darshana Dadhania, John R Lee, Vijay K Sharma, Jenny Xiang, Caroline Suberbielle, Maryvonnick Carmagnat, Nacera Ouali, Eric Rondeau, John J Friedewald, Michael M Abecassis, Manikkam Suthanthiran, Fabien Campagne
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 9, p e1005088 (2016)
Current strategies to improve graft outcome following kidney transplantation consider information at the human leukocyte antigen (HLA) loci. Cell surface antigens, in addition to HLA, may serve as the stimuli as well as the targets for the anti-allog
Externí odkaz:
https://doaj.org/article/98500fdb8f4a4c5c929fe66d7e6095d9
Autor:
Victoria M. Benson, Fabien Campagne
Publikováno v:
PeerJ, Vol 3, p e800 (2015)
Biological data analysis is frequently performed with command line software. While this practice provides considerable flexibility for computationally savy individuals, such as investigators trained in bioinformatics, this also creates a barrier to t
Externí odkaz:
https://doaj.org/article/4fade7c1aeb4438fa7e257d2149d2643
Autor:
Valérie Vingtdeux, Jessica E Tanis, Pallavi Chandakkar, Haitian Zhao, Ute Dreses-Werringloer, Fabien Campagne, J Kevin Foskett, Philippe Marambaud
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112484 (2014)
CALHM1 is a plasma membrane voltage-gated Ca2+-permeable ion channel that controls amyloid-β (Aβ) metabolism and is potentially involved in the onset of Alzheimer's disease (AD). Recently, Rubio-Moscardo et al. (PLoS One (2013) 8: e74203) reported
Externí odkaz:
https://doaj.org/article/dcc9cf9544d840f3a0ff8b8499002e31
Autor:
Manuele Simi, Fabien Campagne
Publikováno v:
PeerJ, Vol 2, p e241 (2014)
Language WorkBenches (LWBs) are software engineering tools that help domain experts develop solutions to various classes of problems. Some of these tools focus on non-technical users and provide languages to help organize knowledge while other workbe
Externí odkaz:
https://doaj.org/article/c4cb093cafbd442d8a4ba16f012fddaa
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79871 (2013)
Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to quickly adap
Externí odkaz:
https://doaj.org/article/2c0a8a2d3a92491eb29c15309f145829
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69666 (2013)
We present GobyWeb, a web-based system that facilitates the management and analysis of high-throughput sequencing (HTS) projects. The software provides integrated support for a broad set of HTS analyses and offers a simple plugin extension mechanism.
Externí odkaz:
https://doaj.org/article/fb358d3c46d04b80bae93ad454dc102b
Autor:
Santiago Ruiz, Haitian Zhao, Christine N. Metz, Fabien Campagne, Julien Papoin, Pallavi Chandakkar, Philippe Marambaud, Lionel Blanc, Erica Christen, Prodyot K. Chatterjee
Publikováno v:
Human Molecular Genetics. 26:4786-4798
Hereditary hemorrhagic telangiectasia (HHT) is a highly debilitating and life-threatening genetic vascular disorder arising from endothelial cell (EC) proliferation and hypervascularization, for which no cure exists. Because HHT is caused by loss-of-
Autor:
Matthew Gillen, Ping Wang, Yousef Al-Abed, Fabien Campagne, Mingzhu He, Li Diao, Haitian Zhao, Aya Nomura-Kitabayashi, Lionel Blanc, Hyunwoo Choi, S. Paul Oh, Philippe Marambaud, Prodyot K. Chatterjee, Pallavi Chandakkar, Radhika Patel, Julien Papoin, Santiago Ruiz, Christine N. Metz
Hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder leading to systemic arteriovenous malformations (AVMs), is caused by loss-of-function mutations in the ALK1-ENG-Smad1/5/8 pathway. Evidence suggests that HHT pathogenesis strong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8473fc22e32495742122408da21c5a44
Autor:
Fabien Campagne, Aya Nomura-Kitabayashi, Mingzhu He, Lionel Blanc, Yousef Al-Abed, Santiago Ruiz, Ping Wang, Christine N. Metz, Haitian Zhao, Pallavi Chandakkar, Radhika Patel, Hyunwoo Choi, S. Paul Oh, Philippe Marambaud, Julien Papoin, Li Diao, Prodyot K. Chatterjee, Matthew Gillen
Publikováno v:
J Clin Invest
Hereditary hemorrhagic telangiectasia (HHT), a genetic bleeding disorder leading to systemic arteriovenous malformations (AVMs), is caused by loss-of-function mutations in the ALK1/ENG/Smad1/5/8 pathway. Evidence suggests that HHT pathogenesis strong