Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Fabien, Serpier"'
Publikováno v:
Synthesis.
An efficient synthesis of 4-mercapto-4-methylpentanoic acid, a fragment notably found in Antibody-Drug Conjugates (ADCs), is reported using an intermolecular radical transfer reaction as the pivotal step. The reported approach displays several advant
Publikováno v:
ACS Catalysis. 11:883-892
There is a strong parallel between simple alcohol oxidation and carbonyl desaturation from both strategic and tactical vantage points. As they both seek to extract hydrogen from an organic substrat...
Publikováno v:
The Journal of Organic Chemistry. 84:4566-4574
The formation of chiral 5- and 7-membered tetrahydrofurans and tetrahydrobenzo[ d]oxepines is achieved via arylative cyclization of simple O-tethered alkyne-enoates in the presence of arylboronic acids and chiral dienes-rhodium catalyst under mild co
Publikováno v:
Angewandte Chemie. 130:10857-10861
Publikováno v:
ACS Catalysis. 7:3410-3413
An addition-carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from N-bridged yne-enoate derivatives, chiral functionalized seven-membered 3-benzazepine heterocycles
Chiral Bicyclo[2.2.2]octa-2,5-dienyltrifluoroborate Derivative as a Useful and Stable Precursor of C
Publikováno v:
Organic letters. 21(11)
A new approach has been developed to prepare monosubstituted C
Publikováno v:
Angewandte Chemie (International ed. in English). 57(33)
A selective, nonchelation-assisted methylation of arenes has been developed. The overall transformation, which combines a C-H functionalization reaction with a nickel-catalyzed cross-coupling, offers rapid access to methylated arenes with high para s
Publikováno v:
ChemInform. 47
A new addition–carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from N-bridged oxoenoate derivatives, highly functionalized piperidines bearing three contiguous
Publikováno v:
Organic letters. 17(21)
A new addition–carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from N-bridged oxoenoate derivatives, highly functionalized piperidines bearing three contiguous
Publikováno v:
ChemInform. 46
Starting from nitrogen-tethered alkynoates and various aryl boronic acids chiral pyrrolidines and piperidines are prepared in moderate to high yields and with high enantioselectivity.