Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fabien, Duveau"'
Autor:
Fabien Duveau, Céline Cordier, Lionel Chiron, Matthias Le Bec, Sylvain Pouzet, Julie Séguin, Artémis Llamosi, Benoit Sorre, Jean-Marc Di Meglio, Pascal Hersen
Publikováno v:
eLife, Vol 12 (2024)
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual fluctuations o
Externí odkaz:
https://doaj.org/article/4e2e1e0106bc43ecada1c04c6af2ec5d
Autor:
Fabien Duveau, Petra Vande Zande, Brian PH Metzger, Crisandra J Diaz, Elizabeth A Walker, Stephen Tryban, Mohammad A Siddiq, Bing Yang, Patricia J Wittkopp
Publikováno v:
eLife, Vol 10 (2021)
Heritable variation in a gene’s expression arises from mutations impacting cis- and trans-acting components of its regulatory network. Here, we investigate how trans-regulatory mutations are distributed within the genome and within a gene regulator
Externí odkaz:
https://doaj.org/article/9117cc5c21474ed4a6d1e59f75783250
Autor:
Fabien Duveau, Céline Cordier, Lionel Chiron, Matthias LeBec, Sylvain Pouzet, Julie Séguin, Artémis Llamosi, B. Sorre, Jean-Marc Di Meglio, Pascal Hersen
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual fluctuations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b32be74c448d7da949868c3ff14826bb
https://doi.org/10.1101/2023.02.17.528926
https://doi.org/10.1101/2023.02.17.528926
Autor:
Fabien Duveau, Andrea Hodgins-Davis, Brian PH Metzger, Bing Yang, Stephen Tryban, Elizabeth A Walker, Tricia Lybrook, Patricia J Wittkopp
Publikováno v:
eLife, Vol 7 (2018)
Gene expression noise is an evolvable property of biological systems that describes differences in expression among genetically identical cells in the same environment. Prior work has shown that expression noise is heritable and can be shaped by sele
Externí odkaz:
https://doaj.org/article/1dcbb6017cd34355858dd28fe6b52266
Autor:
Crisandra J Diaz, Mohammad A Siddiq, Brian P. H. Metzger, Stephen Tryban, Bing Yang, Elizabeth A. Walker, Patricia J. Wittkopp, Fabien Duveau, Petra Vande Zande
Publikováno v:
eLife
eLife, 2021, 10, ⟨10.7554/eLife.67806⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.67806⟩
eLife, Vol 10 (2021)
eLife, 2021, 10, ⟨10.7554/eLife.67806⟩
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.67806⟩
eLife, Vol 10 (2021)
Heritable variation in a gene’s expression arises from mutations impacting cis- and trans-acting components of its regulatory network. Here, we investigate how trans-regulatory mutations are distributed within the genome and within a gene regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02c0bbca6059a2f93418cd68814c28f
https://hal.science/hal-03440690
https://hal.science/hal-03440690
Autor:
Petra Vande Zande, Mohammad A Siddiq, Elizabeth A. Walker, Crisandra J Diaz, Fabien Duveau, Bing Yang, Brian P. H. Metzger, Patricia J. Wittkopp, Stephen Tryban
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633f5e2a73c56851185828a5f361757c
https://doi.org/10.7554/elife.67806.sa2
https://doi.org/10.7554/elife.67806.sa2
Autor:
Fabien, Duveau, Petra, Vande Zande, Brian Ph, Metzger, Crisandra J, Diaz, Elizabeth A, Walker, Stephen, Tryban, Mohammad A, Siddiq, Bing, Yang, Patricia J, Wittkopp
Publikováno v:
eLife
Heritable variation in a gene’s expression arises from mutations impacting cis- and trans-acting components of its regulatory network. Here, we investigate how trans-regulatory mutations are distributed within the genome and within a gene regulator
Mutational sources oftrans-regulatory variation affecting gene expression inSaccharomyces cerevisiae
Autor:
Patricia J. Wittkopp, Stephen Tryban, Crisandra J Diaz, Brian P. H. Metzger, Petra Vande Zande, Elizabeth A. Walker, Mohammad A Siddiq, Fabien Duveau, Bing Yang
Heritable variation in a gene’s expression arises from mutations impactingcis- andtrans-acting components of its regulatory network, with expression variation often derived fromtrans-regulatory mutations within species. Here, we investigate howtran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41e93c1fe282ccb3dc90c14354a1f6f1
https://doi.org/10.1101/2021.02.22.432283
https://doi.org/10.1101/2021.02.22.432283
Autor:
Fabien Duveau, Marie-Anne Félix
Publikováno v:
PLoS Biology, Vol 10, Iss 1, p e1001230 (2012)
Robust biological systems are expected to accumulate cryptic genetic variation that does not affect the system output in standard conditions yet may play an evolutionary role once phenotypically expressed under a strong perturbation. Genetic variatio
Externí odkaz:
https://doaj.org/article/6b2152cb266545e9a16afaf3cc6ccc35
Publikováno v:
Molecular Biology and Evolution. 34:2908-2912
Variation in gene expression is widespread within and between species, but fitness consequences of this variation are generally unknown. Here we use mutations in theSaccharomyces cerevisiae TDH3promoter to assess how changes inTDH3expression affect c