Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Fabiana Paladini"'
Autor:
Benedetta Mattorre, Valentina Tedeschi, Giorgia Paldino, Maria Teresa Fiorillo, Fabiana Paladini, Rosa Sorrentino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The Endoplasmic Reticulum Aminopeptidase 1 and 2 (ERAP1 and ERAP2) and Insulin Regulated Aminopeptidase (IRAP) are three M1 zinc metalloproteases whose role in antigen processing is the refining of peptidome either in the Endoplasmic reticulum (ERAP1
Externí odkaz:
https://doaj.org/article/e2e8869bb6ff4dc5a93abc3cb7055714
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/c44575cda99442478eb62fbe4b1a12a5
Autor:
Fabiana Paladini, Maria Teresa Fiorillo, Valentina Tedeschi, Benedetta Mattorre, Rosa Sorrentino
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In the human genome, the aminopeptidases ERAP1, ERAP2 and LNPEP lie contiguously on chromosome 5. They share sequence homology, functions and associations with immune-mediated diseases. By analyzing their multifaceted activities as well as their expr
Externí odkaz:
https://doaj.org/article/114ddff4fe3b43d2b504262d7a3fa827
Autor:
Fabiana Paladini, Maria Teresa Fiorillo, Valentina Tedeschi, Alberto Cauli, Alessandro Mathieu, Rosa Sorrentino
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies. So far only two alleles, t
Externí odkaz:
https://doaj.org/article/b3a224e1307e40208ba7a63ade5ec768
Autor:
Valentina Tedeschi, Carolina Vitulano, Alberto Cauli, Fabiana Paladini, Matteo Piga, Alessandro Mathieu, Rosa Sorrentino, Maria Teresa Fiorillo
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 215-223 (2016)
Abstract HLA-B*27 is strongly associated with an inflammatory autoimmune disorder, the Ankylosing Spondylitis (AS) and plays a protective role in viral infections. The two aspects might be linked. In this work, we compared in B*2705/B*07 positive pat
Externí odkaz:
https://doaj.org/article/bd4534d7e4d64cafb849bade7ade8629
Autor:
Maria Maddalena Angioni, Matteo Piga, Fabiana Paladini, Sara Lai, Gian Luca Erre, Alberto Floris, Alberto Cauli, Maria Teresa Fiorillo, Giuseppe Passiu, Carlo Carcassi, Rosa Sorrentino, Alessandro Mathieu
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204250 (2018)
BACKGROUND:Behçet's disease (BD) is a polygenic immune-mediated disorder characterized by a close association with the HLA-B*51 allele. The HLA region has a strong linkage disequilibrium (LD) and carries several genetic variants (e.g. MIC-A, TNF-α
Externí odkaz:
https://doaj.org/article/03d38527abbe4dc5899f8c47e1be8fc2
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/6fe0c47aeafd4abb8c7022005306cfdc
Autor:
Valentina Tedeschi, Josephine Alba, Fabiana Paladini, Marino Paroli, Alberto Cauli, Alessandro Mathieu, Rosa Sorrentino, Marco D’Abramo, Maria Teresa Fiorillo
Publikováno v:
Cells, Vol 8, Iss 6, p 572 (2019)
The human leukocyte antigen HLA-B27 is a strong risk factor for Ankylosing Spondylitis (AS), an immune-mediated disorder affecting axial skeleton and sacroiliac joints. Additionally, evidence exists sustaining a strong protective role for HLA-B27 in
Externí odkaz:
https://doaj.org/article/eeb2d16cc1614b50962d32f2f794c5e7
Autor:
Fabiana Paladini, Nicla Porciello, Giorgio Camilli, Sinem Tuncer, Elisa Cocco, Maria Teresa Fiorillo, Rosa Sorrentino
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112646 (2014)
Complex immune and neurodegenerative disorders are the result of multiple interactions between common genetic variations having, individually, a weak effect on the disease susceptibility or resistance. Interestingly, some genes have been found to be
Externí odkaz:
https://doaj.org/article/8eb0e69d7dfc44d3873b223d54eac904
Autor:
Elisa Cocco, Fabiana Paladini, Giuseppe Macino, Valerio Fulci, Maria Teresa Fiorillo, Rosa Sorrentino
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12067 (2010)
BACKGROUND: The human Vasoactive Intestinal Peptide (VIP) is a neurokine with effects on the immune system where it is involved in promoting tolerance. In this context, one of its receptors, VPAC1, has been found to be down-modulated in cells of the
Externí odkaz:
https://doaj.org/article/5dd4aa7b0ed644ac873af3e48699ffe9