Effect of Upadacitinib on Quality of Life and Work Productivity in Active Non-radiographic Axial Spondyloarthritis: Results From Randomized Phase 3 Trial SELECT-AXIS 2

Autor: Uta Kiltz, Mitsumasa Kishimoto, Jessica A. Walsh, Percival Sampaio-Barros, Manish Mittal, Christopher D. Saffore, Peter Wung, Fabiana Ganz, Ana Biljan, Denis Poddubnyy

Publikováno v: Rheumatology and Therapy, Vol 10, Iss 4, Pp 887-899 (2023)

Abstract Introduction To evaluate the effect of upadacitinib vs. placebo on health-related quality of life (HRQoL) and work productivity in patients with active non-radiographic axial spondyloarthritis (nr-axSpA) enrolled in the SELECT-AXIS 2 phase 3

Externí odkaz: https://doaj.org/article/a6045f141e974a17bdd766dccb252caf

Effect of Upadacitinib on Disease Activity, Pain, Fatigue, Function, Health-Related Quality of Life and Work Productivity for Biologic Refractory Ankylosing Spondylitis

Autor: Victoria Navarro-Compán, Xenofon Baraliakos, Marina Magrey, Andrew Östör, Christopher D. Saffore, Manish Mittal, In-Ho Song, Fabiana Ganz, Jayne Stigler, Atul Deodhar

Publikováno v: Rheumatology and Therapy, Vol 10, Iss 3, Pp 679-691 (2023)

Abstract Introduction Patients with ankylosing spondylitis (AS) have significant unmet treatment needs, despite advancements in biologic therapies. This study evaluated the impact of upadacitinib on clinically meaningful improvement in patient-report

Externí odkaz: https://doaj.org/article/4c4e65cdcd924c5cbdacdf4e4e9d1654

LOOP, a cross-sectional, observational study investigating the clinical specialty setting as a determinant of disease management in psoriatic arthritis: Subgroup analysis results from Japan.

Autor: Masato Okada, Sarina Kurimoto, Fabiana Ganz, Wolf-Henning Boehncke

Publikováno v: PLoS ONE, Vol 16, Iss 1, p e0245954 (2021)

BackgroundPsoriatic arthritis (PsA) is a progressive erosive joint disorder that causes functional impairment; therefore, early diagnosis and management are essential. This study evaluated the association between clinical specialty and the time to ma

Externí odkaz: https://doaj.org/article/6a98db90074243f5a1aee9bd0ccc29a6

OA38 Efficacy and safety of upadacitinib in patients with psoriatic arthritis and axial involvement

Autor: Atul Deodhar, Roberto Ranza, Fabiana Ganz, Tianming Gao, Jaclyn Anderson, Andrew Ostor

Publikováno v: Rheumatology. 61

Background/Aims Patients (pts) with psoriatic arthritis (PsA) and axial involvement exhibit greater disease activity and quality of life impairments compared with those without axial involvement. Here the aim was to characterize PsA pts with and with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21680c29973beb47cc45bbad2793a3a1
https://doi.org/10.1093/rheumatology/keac132.038

Site-specific resolution of enthesitis in patients with axial spondyloarthritis treated with tumor necrosis factor inhibitors

Autor: Fabiana Ganz, Martin Schulz, Burkhard Möller, Adrain Ciurea, Almut Scherer, Michael John Nissen, P. Zueger, Eleftherios Papagiannoulis, Ruediger B Mueller, Thomas Hügle

Publikováno v: Arthritis Research & Therapy
Arthritis research & therapy, Vol. 23, No 1 (2021) P. 165
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)

Background Enthesitis is a hallmark of spondyloarthritis (SpA) with a substantial impact on quality of life. Reports of treatment effectiveness across individual enthesitis sites in real-world patients with axial SpA (axSpA) are limited. We investiga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a353962cc87e55ed9b6226407cf533d1
http://europepmc.org/articles/PMC8188725