Výsledky vyhledávání - "Fabiana C. Vilela"

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Akademický článek

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Curcumin prevents sickness behavior and fever by the modulation of Nrf2 activity in a model of endotoxemia

Autor: Viviana Carolina Trujillo Rojas, Fabiana C. Vilela, Letícia Reis, Fernando Vitor-Vieira, Merelym Ketterym de Oliveira, Elisa S Estevam, Alexandre Giusti-Paiva, Tatiane Helena Batista

Lipopolysaccharide (LPS) is a potent inducer of inflammation, triggering behavioral changes and fever. The present study aimed to evaluate whether pretreatment with curcumin prevents the behavioral changes and fever induced by LPS through the modulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db9b45f5538f840aab078c0ec6dbdc56
https://doi.org/10.21203/rs.3.rs-879472/v1

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Design, Synthesis and Pharmacological Evaluation of Novel Antiinflammatory and Analgesic O-Benzyloxime Compounds Derived From Natural Eugenol

Autor: Fabiano Veiga, Roberta Tesch, André Victor Pereira, Alexandre Giusti-Paiva, Danielle Ferreira Dias, Carlos A. M. Fraga, Claudio Viegas, Rodrigo César da Silva, Marcia Paranho Veloso, Fabiana C. Vilela, Thayssa Tavares da Silva Cunha

Publikováno v: Letters in Drug Design & Discovery. 16:1157-1166

Background: : A new series of O-benzyloximes derived from eugenol was synthesized and was evaluated for its antinociceptive and anti-inflammatory properties. Methods: : The target compounds were obtained in good global 25-28% yields over 6 steps, whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26ed53ccc8cfaecbdc436d06a752eb50
https://doi.org/10.2174/1570180815666180620145609

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Curcumin attenuates LPS-induced sickness behavior and fever in rats by modulating Nrf2 activity

Autor: Letícia, Reis, Merelym K, Oliveira, Viviana Carolina T, Rojas, Tatiane H, Batista, Elisa S, Estevam, Fernando, Vitor-Vieira, Fabiana C, Vilela, Alexandre, Giusti-Paiva

Publikováno v: Neuroscience Letters. 781:136680

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71947bf2ae4b0d9ba8cb6a6136a7958e
https://doi.org/10.1016/j.neulet.2022.136680

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The accentuation in post-traumatic stress disorder-like symptoms induced by diabetes in rats is not associated with a further increase in astrocyte activation in the hippocampus

Autor: Alexandre Giusti-Paiva, Tatiane Helena Batista, Ana Cláudia Alves Freire Ribeiro, Mariela S. Ferrari, Fabiana C. Vilela

Publikováno v: Neuroscience letters. 762

Individuals with post-traumatic stress disorder (PTSD) show increased rates of several serious metabolic diseases. However, little is known about pre-existing metabolic diseases and the development of PTSD. Therefore, we aimed to evaluate the course

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33a2a46d142b18d75be099eace1e4f1
https://pubmed.ncbi.nlm.nih.gov/34400287

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Hyperactivation of the amygdala correlates with impaired social play behavior of prepubertal male rats in a maternal immune activation model

Autor: Alexandre Giusti-Paiva, Fabiana C. Vilela, Fernando Vitor-Vieira

Publikováno v: Behavioural brain research. 414

Maternal infection during pregnancy is an environmental risk factor for neurodevelopmental dysfunction, such as autism spectrum disorder (ASD). This study investigated the effect of maternal immune activation (MIA) on the behavior profile of prepuber

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbbfdc4e294116797d9278c0fb7771d
https://pubmed.ncbi.nlm.nih.gov/34331970

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Maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus

Autor: Fabiana C. Vilela, Josie Resende Torres da Silva, Jádina S. Vieira, Marcelo Lourenço da Silva, Fernando Vitor-Vieira, Bruna Kalil-Cutti, Alexandre Giusti-Paiva

Publikováno v: Neuroscience letters. 748

Animals subjected to early life maternal separation exhibit increased sensitivity to chemical, thermal, and mechanical stimuli during adulthood. However, the mechanism by which maternal separation can alter pain sensitivity in adulthood has not yet b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f019d006f3a633308641775c8641bc
https://pubmed.ncbi.nlm.nih.gov/33596470

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Ghrelin receptor antagonist attenuated sickness behavior and activation of HPA-axis induced by immunological challenge in male rats

Autor: Delcio E. Paula, Alexandre Giusti-Paiva, Fabiana C. Vilela

Publikováno v: Life Sciences. 288:120173

AIMS During illnesses caused by infectious diseases, a suite of brain-mediated responses called sickness syndrome occurs, triggering behavioral and physiological changes. This study investigated whether ghrelin modulates sickness syndrome induced by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57dead1c215a99f336da805fa076e0f
https://doi.org/10.1016/j.lfs.2021.120173

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