Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fabiana, Quagliarini"'
Publikováno v:
European Journal of Endocrinology. 188:R111-R130
Glucocorticoids are essential hormones produced by the adrenal cortex with prominent circadian rhythmicity and in times of stress. Glucocorticoids maintain liver homeostasis through coordinated activities that control the major pathways of energy met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9edbe646e0b1bf1883f9754ee7d7a678
https://doi.org/10.1093/ejendo/lvad048
https://doi.org/10.1093/ejendo/lvad048
Autor:
Sara Della Torre, Nico Mitro, Roberta Fontana, Monica Gomaraschi, Elda Favari, Camilla Recordati, Federica Lolli, Fabiana Quagliarini, Clara Meda, Claes Ohlsson, Maurizio Crestani, Nina Henriette Uhlenhaut, Laura Calabresi, Adriana Maggi
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 360-371 (2016)
Lipoprotein synthesis is controlled by estrogens, but the exact mechanisms underpinning this regulation and the role of the hepatic estrogen receptor α (ERα) in cholesterol physiology are unclear. Utilizing a mouse model involving selective ablatio
Externí odkaz:
https://doaj.org/article/69182fe8a93b480498c4f40c730eeded
Autor:
Kenneth Allen Dyar, Michaël Jean Hubert, Ashfaq Ali Mir, Stefano Ciciliot, Dominik Lutter, Franziska Greulich, Fabiana Quagliarini, Maximilian Kleinert, Katrin Fischer, Thomas Oliver Eichmann, Lauren Emily Wright, Marcia Ivonne Peña Paz, Alberto Casarin, Vanessa Pertegato, Vanina Romanello, Mattia Albiero, Sara Mazzucco, Rosario Rizzuto, Leonardo Salviati, Gianni Biolo, Bert Blaauw, Stefano Schiaffino, N Henriette Uhlenhaut
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2005886 (2018)
Circadian clocks are fundamental physiological regulators of energy homeostasis, but direct transcriptional targets of the muscle clock machinery are unknown. To understand how the muscle clock directs rhythmic metabolism, we determined genome-wide b
Externí odkaz:
https://doaj.org/article/2baff020749c46b7943454ca2b934a95
Autor:
Franziska Greulich, Michael Wierer, Fabiana Quagliarini, Nina Henriette Uhlenhaut, Laura Escoter-Torres
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research (London)
Nucleic Acids Research (London)
The glucocorticoid receptor is an important immunosuppressive drug target and metabolic regulator that acts as a ligand-gated transcription factor. Generally, GR’s anti-inflammatory effects are attributed to the silencing of inflammatory genes, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2844df5d6b9323b54de4e7193b071cac
Autor:
Ashfaq Ali, Mir, Kenneth Allen, Dyar, Franziska, Greulich, Fabiana, Quagliarini, Céline, Jouffe, Michaël Jean, Hubert, Marie Charlotte, Hemmer, Nina Henriette, Uhlenhaut
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1966
Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-seq) is a powerful tool to map context-dependent genome-wide binding of nuclear hormone receptors and their coregulators. This information can provide important mechanistic ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e60fb157523d7cd4534f3ae1b77b803
https://pubmed.ncbi.nlm.nih.gov/31041738
https://pubmed.ncbi.nlm.nih.gov/31041738
Autor:
Fabiana Quagliarini, Franziska Greulich, Ashfaq Ali Mir, Céline Jouffe, Marie Charlotte Hemmer, Nina Henriette Uhlenhaut, Michaël Jean Hubert, Kenneth A. Dyar
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991945
Chromatin immunoprecipitation coupled to next generation sequencing (ChIP-seq) is a powerful tool to map context-dependent genome-wide binding of nuclear hormone receptors and their coregulators. This information can provide important mechanistic ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6ce1d9d8d69852f8f16ad2650d994b
https://doi.org/10.1007/978-1-4939-9195-2_5
https://doi.org/10.1007/978-1-4939-9195-2_5
Autor:
Thomas O. Eichmann, Mattia Albiero, Alberto Casarin, Michaël Jean Hubert, Vanessa Pertegato, Maximilian Kleinert, Katrin Fischer, Fabiana Quagliarini, Bert Blaauw, Vanina Romanello, S. Mazzucco, Ashfaq Ali Mir, Franziska Greulich, Rosario Rizzuto, Gianni Biolo, Dominik Lutter, Stefano Schiaffino, Leonardo Salviati, Marcia Ivonne Peña Paz, Stefano Ciciliot, Lauren E. Wright, Kenneth A. Dyar, N. Henriette Uhlenhaut
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 8, p e2005886 (2018)
PLoS Biol. 16:e2005886 (2018)
PLoS Biology, Vol 16, Iss 8, p e2005886 (2018)
PLoS Biol. 16:e2005886 (2018)
Circadian clocks are fundamental physiological regulators of energy homeostasis, but direct transcriptional targets of the muscle clock machinery are unknown. To understand how the muscle clock directs rhythmic metabolism, we determined genome-wide b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144d0dd747e2575e3331938e8e842bdb
http://hdl.handle.net/10044/1/61816
http://hdl.handle.net/10044/1/61816
Autor:
Kenneth A. Dyar, Johann Hawe, Grant D. Barish, Ashfaq Ali Mir, Matthias Heinig, Céline Jouffe, Kinga Balazs, Konstantinos Makris, Fabian V. Filipp, Nina Henriette Uhlenhaut, Michael Wierer, Fabiana Quagliarini
Publikováno v:
Molecular Cell
Mol Cell
Mol Cell
Summary The glucocorticoid receptor (GR) is a potent metabolic regulator and a major drug target. While GR is known to play integral roles in circadian biology, its rhythmic genomic actions have never been characterized. Here we mapped GR’s chromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c945534d293697319a7f8d29d5b1a1
https://doi.org/10.1038/s41574-019-0297-0
https://doi.org/10.1038/s41574-019-0297-0
Autor:
Jonathan C. Cohen, Viktoria Gusarova, Jesper Gromada, Helen H. Hobbs, Fabiana Quagliarini, David M. Valenzuela, Yan Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 110:16109-16114
Angiopoietin-like protein (ANGPTL)8 (alternatively called TD26, RIFL, Lipasin, and Betatrophin) is a newly recognized ANGPTL family member that has been implicated in both triglyceride (TG) and glucose metabolism. Hepatic overexpression of ANGPTL8 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b072fd95e47edca858816fc8af9abda
https://doi.org/10.1073/pnas.1315292110
https://doi.org/10.1073/pnas.1315292110
Autor:
Yan Wang, Rhonda Hyde, Helen H. Hobbs, Jonathan C. Cohen, Nick V. Grishin, Eric Boerwinkle, Andrew J. Murphy, Fabiana Quagliarini, David M. Valenzuela, Julia Kozlitina
Publikováno v:
Proceedings of the National Academy of Sciences. 109:19751-19756
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3 , a gene located in an intron of DOCK7 , results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11889dc8ecf8326c6d639851663ae95b
https://doi.org/10.1073/pnas.1217552109
https://doi.org/10.1073/pnas.1217552109