Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Fabian Stimpfle"'
Autor:
Dominik Rath, Madhumita Chatterjee, Angela Bongartz, Karin Müller, Michal Droppa, Fabian Stimpfle, Oliver Borst, Christine Zuern, Sebastian Vogel, Meinrad Gawaz, Tobias Geisler
Publikováno v:
Platelets, Vol 28, Iss 1, Pp 34-39 (2017)
Platelet surface expression levels of stromal cell derived factor 1 (SDF-1) are elevated in acute coronary syndrome and associated with LVEF% improvement after myocardial infarction (MI). Platelet SDF-1 might facilitate thrombus formation and endomyo
Externí odkaz:
https://doaj.org/article/069f85185eec4390b98c52c4204b09aa
Autor:
Fabian Stimpfle, Maike Bauer, Dominik Rath, Elke Schaeffeler, Matthias Schwab, Meinrad Gawaz, Stefan Winter, Tobias Geisler
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Introduction: Platelet endothelial aggregation receptor 1 (PEAR1) triggers platelet aggregation and is expressed in platelets and endothelial cells. Genome-wide association studies (GWAS) showed an association between platelet function and single-nuc
Externí odkaz:
https://doaj.org/article/233186551c1642079317e6a401bb5ca1
Autor:
Dominik Rath, Elke Schaeffeler, Stefan Winter, Semjon Levertov, Karin Müller, Michal Droppa, Fabian Stimpfle, Harald F. Langer, Meinrad Gawaz, Matthias Schwab, Tobias Geisler
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
BackgroundPlatelet membrane glycoprotein receptors mediate thrombus formation. GP Ia/IIa is an essential platelet integrin receptor. Single-nucleotide polymorphisms (SNPs) of the GP Ia/IIa gene alter GP Ia/IIa expression; however, their influence on
Externí odkaz:
https://doaj.org/article/8a1ea83273fb43cea2aa277510c9ba59
Autor:
Dominik Rath, Elke Schaeffeler, Stefan Winter, Jens Hewer, Karin Müller, Michal Droppa, Fabian Stimpfle, Meinrad Gawaz, Matthias Schwab, Tobias Geisler
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161933 (2016)
BACKGROUND:SDF1 and its cognate receptors CXCR4 and CXCR7 are involved in myocardial repair and are associated with outcome in cardiovascular patients. Hence, we aimed to investigate clinically significant SDF1 SNPs for their prognostic impact in pat
Externí odkaz:
https://doaj.org/article/176d6560e0434f53bd4ad95f47ea3597
Autor:
Michal Droppa, Dimitri Tschernow, Karin A L Müller, Elli Tavlaki, Athanasios Karathanos, Fabian Stimpfle, Elke Schaeffeler, Matthias Schwab, Alexander Tolios, Jolanta M Siller-Matula, Meinrad Gawaz, Tobias Geisler
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121620 (2015)
ObjectivesThis study was designed to identify the multivariate effect of clinical risk factors on high on-treatment platelet reactivity (HPR) and 12 months major adverse events (MACE) under treatment with aspirin and clopidogrel in patients undergoin
Externí odkaz:
https://doaj.org/article/775d73fa4fac46018ff90fce1276719a
Autor:
Tobias Geisler, Fabian Stimpfle
Publikováno v:
Der Klinikarzt. 48:384-395
ZUSAMMENFASSUNGDie korrekte Behandlung der Lungenarterienembolie beginnt mit einer frühzeitigen multimodalen Einschätzung des Risikos unter Berücksichtigung der klinischen Vorhersagekraft, Laborparametern und bildmorphologischen Risikomerkmalen. W
Autor:
Jessica Kristin, Henes, Patrick, Groga-Bada, Elke, Schaeffeler, Stefan, Winter, Luis, Hack, Monika, Zdanyte, Karin, Mueller, Michal, Droppa, Fabian, Stimpfle, Meinrad, Gawaz, Harald, Langer, Matthias, Schwab, Tobias, Geisler, Dominik, Rath
Publikováno v:
Pharmacogenomics and Personalized Medicine
Background Complement component 5a (C5a) is a highly potent anaphylatoxin with a variety of pro-inflammatory effects. C5a contributes to progression of atherosclerosis and inhibition of the receptor (C5aR) might offer a therapeutic strategy in this r
Autor:
Tobias Geisler, Fabian Stimpfle
Publikováno v:
Der Klinikarzt. 47:86-94
ZusammenfassungHäufigste Ursache einer Lungenarterienembolie (LAE) ist eine venöse Thromboembolie in Folge einer tiefen Beinvenenthrombose (TBVT). Entsprechend der aktuellen Leitlinien, ist bei TVBT oder LAE eine Antikoagulation für mindestens 3 M
Autor:
J Flassak, Martin Duckheim, Christian Scheckenbach, Fabian Stimpfle, Juergen Schreieck, Peter Seizer, David Heinzmann, U Yurtbil, M. Gawaz
Publikováno v:
European Heart Journal. 40
Background Short duration 50 Watt radiofrequency (RF) ablation has been shown to be feasible for atrial fibrillation (AF) ablation with short procedure times. Purpose We evaluated 50 Watt RF power with a different fixed short application duration at
Autor:
P Groga-Bada, F Heller, Michal Droppa, Elke Schaeffeler, M. Gawaz, Matthias Schwab, Tobias Geisler, Dominik Rath, Karin Mueller, L P Hack, Stefan Winter, N Lente, Fabian Stimpfle
Publikováno v:
European Heart Journal. 40
Background Matrix Metalloproteinase-2 (MMP-2) is involved in regulation and proliferation of vascular and endothelial cells and is therefore an important component of atherosclerotic vessels. Inhibition of MMP-2 activity is associated with improvemen