Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Fabian Segovia-Miranda"'
Autor:
Lucas Opazo-Rios, Manuel Soto-Catalan, Iolanda Lázaro, Aleix Sala-Vila, Cristian Pérez-Gallardo, Fabian Segovia-Miranda, Juan Antonio Moreno, Jesús Egido, Sebastián Mas-Fontao
Publikováno v:
Annals of Hepatology, Vol 28, Iss , Pp 100906- (2023)
Introduction and Objectives: The new recommendations suggesting changing the current nomenclature from Non-Alcoholic Fatty Liver Disease (NAFLD) to Metabolic associated fatty liver disease (MAFLD) are primarily aimed at improving the understanding of
Externí odkaz:
https://doaj.org/article/c872cd79e05b4246a16d87507c1b5579
Autor:
Sofía Espinoza, Sebastián B. Arredondo, Francisca Barake, Francisco Carvajal, Fernanda G. Guerrero, Fabian Segovia-Miranda, David M. Valenzuela, Ursula Wyneken, Alejandro Rojas-Fernández, Waldo Cerpa, Loreto Massardo, Lorena Varela-Nallar, Alfonso González
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated
Externí odkaz:
https://doaj.org/article/706d6d1a38ce4746a112602d79945e18
Autor:
Nicolás Albornoz, Javiera Álvarez-Indo, Adely de la Peña, Eloisa Arias-Muñoz, Alanis Coca, Fabián Segovia-Miranda, Bredford Kerr, Mauricio Budini, Alfredo Criollo, María A. García-Robles, Eugenia Morselli, Andrea Soza, Patricia V. Burgos
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Objective Obesity represents a significant global health challenge characterized by chronic low-grade inflammation and metabolic dysregulation. The hypothalamus, a key regulator of energy homeostasis, is particularly susceptible to obesity
Externí odkaz:
https://doaj.org/article/f63beb9cd74e48138cb1f2d39aa6903b
Autor:
Ricardo Fuentes, Florence L Marlow, Elliott W Abrams, Hong Zhang, Manami Kobayashi, Tripti Gupta, Lee D Kapp, Zachary DiNardo, Ronald Heller, Ruth Cisternas, Priscila García-Castro, Fabián Segovia-Miranda, Felipe Montecinos-Franjola, William Vought, Charles E Vejnar, Antonio J Giraldez, Mary C Mullins
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011343 (2024)
Maternally-loaded factors in the egg accumulate during oogenesis and are essential for the acquisition of oocyte and egg developmental competence to ensure the production of viable embryos. However, their molecular nature and functional importance re
Externí odkaz:
https://doaj.org/article/7b554f9630d24ed5ab8a433a491aeb11
Autor:
Dilan Martínez-Torres, Valentina Maldonado, Cristian Pérez-Gallardo, Rodrigo Yañez, Valeria Candia, Yannis Kalaidzidis, Marino Zerial, Hernán Morales-Navarrete, Fabián Segovia-Miranda
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Three-dimensional (3D) geometrical models are potent tools for quantifying complex tissue features and exploring structure–function relationships. However, these models are generally incomplete due to experimental limitations in acquiring
Externí odkaz:
https://doaj.org/article/b2460d5358c5496790d7f3c684a3f7d2
Autor:
Dilan Martinez, Maldonado Valentina, Cristian Perez, Valeria Candia, Hernán Morales-Navarrete, Fabián Segovia-Miranda
Publikováno v:
Annals of Hepatology, Vol 28, Iss , Pp 100909- (2023)
Introduction and Objectives: The liver is an organ that performs a wide variety of functions that are highly dependent on its complex 3D structure. Geometrical models (digital representations of tissues) represent a versatile technique to characteriz
Externí odkaz:
https://doaj.org/article/2edaf68ded3943d79d943af54ef17bdd
Autor:
André Scholich, Simon Syga, Hernán Morales-Navarrete, Fabián Segovia-Miranda, Hidenori Nonaka, Kirstin Meyer, Walter de Back, Lutz Brusch, Yannis Kalaidzidis, Marino Zerial, Frank Jülicher, Benjamin M Friedrich
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1009349 (2021)
[This corrects the article DOI: 10.1371/journal.pcbi.1008412.].
Externí odkaz:
https://doaj.org/article/562e92c4e98747b8bd823ffd68969ef9
Autor:
André Scholich, Simon Syga, Hernán Morales-Navarrete, Fabián Segovia-Miranda, Hidenori Nonaka, Kirstin Meyer, Walter de Back, Lutz Brusch, Yannis Kalaidzidis, Marino Zerial, Frank Jülicher, Benjamin M Friedrich
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008412 (2020)
How epithelial cells coordinate their polarity to form functional tissues is an open question in cell biology. Here, we characterize a unique type of polarity found in liver tissue, nematic cell polarity, which is different from vectorial cell polari
Externí odkaz:
https://doaj.org/article/a411acdfd1eb43caad3cd203f6095013
Autor:
Hernán Morales-Navarrete, Hidenori Nonaka, André Scholich, Fabián Segovia-Miranda, Walter de Back, Kirstin Meyer, Roman L Bogorad, Victor Koteliansky, Lutz Brusch, Yannis Kalaidzidis, Frank Jülicher, Benjamin M Friedrich, Marino Zerial
Publikováno v:
eLife, Vol 8 (2019)
Functional tissue architecture originates by self-assembly of distinct cell types, following tissue-specific rules of cell-cell interactions. In the liver, a structural model of the lobule was pioneered by Elias in 1949. This model, however, is in co
Externí odkaz:
https://doaj.org/article/33e29e9f287b4b73becdf7cfdc1d6f67
Autor:
Dorian Obino, Luc Fetler, Andrea Soza, Odile Malbec, Juan José Saez, Mariana Labarca, Claudia Oyanadel, Felipe Del Valle Batalla, Nicolas Goles, Aleksandra Chikina, Danielle Lankar, Fabián Segovia-Miranda, Camille Garcia, Thibaut Léger, Alfonso Gonzalez, Marion Espéli, Ana-Maria Lennon-Duménil, Maria-Isabel Yuseff
Publikováno v:
Cell Reports, Vol 25, Iss 11, Pp 3110-3122.e6 (2018)
Summary: Complete activation of B cells relies on their capacity to extract tethered antigens from immune synapses by either exerting mechanical forces or promoting their proteolytic degradation through lysosome secretion. Whether antigen extraction
Externí odkaz:
https://doaj.org/article/cad33fed519b4f1fb48c44bd48bb7a3b