Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fabian N. Bangel"'
Autor:
Judith M. van der Harg, Leslie Eggels, Fabian N. Bangel, Silvie R. Ruigrok, Rob Zwart, Jeroen J.M. Hoozemans, Susanne E. la Fleur, Wiep Scheper
Publikováno v:
Neurobiology of Disease, Vol 103, Iss , Pp 163-173 (2017)
Alzheimer's disease (AD) is a highly prevalent multifactorial disease for which Diabetes Mellitus (DM) is a risk factor. Abnormal phosphorylation and aggregation of tau is a key hallmark of AD. In animal models, DM induces or exacerbates the phosphor
Externí odkaz:
https://doaj.org/article/dd361cd919f04c81abebee5746c8e7ab
Autor:
Susanne E. la Fleur, Leslie Eggels, Fabian N. Bangel, Judith M. van der Harg, Silvie R. Ruigrok, Wiep Scheper, Rob Zwart, Jeroen J.M. Hoozemans
Publikováno v:
Neurobiology of Disease, Vol 103, Iss, Pp 163-173 (2017)
Neurobiology of Disease, 103, 163-173. Academic Press Inc.
van der Harg, J M, Eggels, L, Bangel, F N, Ruigrok, S R, Zwart, R, Hoozemans, J J M, la Fleur, S E & Scheper, W 2017, ' Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation ', Neurobiology of Disease, vol. 103, pp. 163-173 . https://doi.org/10.1016/j.nbd.2017.04.005
Neurobiology of disease, 103, 163-173. Academic Press Inc.
Neurobiology of Disease, 103, 163-173. Academic Press Inc.
van der Harg, J M, Eggels, L, Bangel, F N, Ruigrok, S R, Zwart, R, Hoozemans, J J M, la Fleur, S E & Scheper, W 2017, ' Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation ', Neurobiology of Disease, vol. 103, pp. 163-173 . https://doi.org/10.1016/j.nbd.2017.04.005
Neurobiology of disease, 103, 163-173. Academic Press Inc.
Alzheimer's disease (AD) is a highly prevalent multifactorial disease for which Diabetes Mellitus (DM) is a risk factor. Abnormal phosphorylation and aggregation of tau is a key hallmark of AD. In animal models, DM induces or exacerbates the phosphor
Autor:
Wiep Scheper, Judith M. van der Harg, Jessica C. van Heest, Fabian N. Bangel, Jan R.T. van Weering, Sanne Patiwael
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research, 1864(4), 655-665. Elsevier
van der Harg, J M, van Heest, J C, Bangel, F N, Patiwael, S, van Weering, J R T & Scheper, W 2017, ' The UPR reduces glucose metabolism via IRE1 signaling ', Biochimica et Biophysica Acta, vol. 1864, no. 4, pp. 655-665 . https://doi.org/10.1016/j.bbamcr.2017.01.009
Biochimica et Biophysica Acta, 1864(4), 655-665. Elsevier
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1864(4), 655-665. Elsevier
van der Harg, J M, van Heest, J C, Bangel, F N, Patiwael, S, van Weering, J R T & Scheper, W 2017, ' The UPR reduces glucose metabolism via IRE1 signaling ', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1864, no. 4, pp. 655-665 . https://doi.org/10.1016/j.bbamcr.2017.01.009
van der Harg, J M, van Heest, J C, Bangel, F N, Patiwael, S, van Weering, J R T & Scheper, W 2017, ' The UPR reduces glucose metabolism via IRE1 signaling ', Biochimica et Biophysica Acta, vol. 1864, no. 4, pp. 655-665 . https://doi.org/10.1016/j.bbamcr.2017.01.009
Biochimica et Biophysica Acta, 1864(4), 655-665. Elsevier
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1864(4), 655-665. Elsevier
van der Harg, J M, van Heest, J C, Bangel, F N, Patiwael, S, van Weering, J R T & Scheper, W 2017, ' The UPR reduces glucose metabolism via IRE1 signaling ', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1864, no. 4, pp. 655-665 . https://doi.org/10.1016/j.bbamcr.2017.01.009
Neurons are highly dependent on glucose. A disturbance in glucose homeostasis therefore poses a severe risk that is counteracted by activation of stress responses to limit damage and restore the energy balance. A major stress response that is activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35745145efa5aeaec49d9185648eff9
https://research.vumc.nl/en/publications/038a8192-6935-4105-af59-97f796be0825
https://research.vumc.nl/en/publications/038a8192-6935-4105-af59-97f796be0825
Autor:
Takeo Yoshikawa, Masanari Itokawa, Shabeesh Balan, Norio Mori, Yasuhide Iwata, Tasuku Hashimoto, Oliver Stork, Mitsuru Kikuchi, Nobuhisa Kanahara, Katsuaki Suzuki, Makoto Arai, Yoshimi Iwayama, Kazuo Yamada, Fabian N. Bangel, Tomoko Toyota
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 59
Recent reports suggest that carbonyl stress might affect a subset of schizophrenia patients suffering from severe symptoms. Carbonyl stress protection is achieved by the glyoxalase system consisting of two enzymes, glyoxalase 1 and 2, which in humans