Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Fabian López-Vallejo"'
Publikováno v:
RSC Advances. 12:6783-6790
Transcription factors associated with quorum sensing in P. aeruginosa are promising targets for developing new adjuvants against infection by this pathogen. Regulation of these transcription factors offers the possibility of controlling multiple viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d854aa257d33e1df5d89d3953f302e0
https://doi.org/10.1039/d1ra08352j
https://doi.org/10.1039/d1ra08352j
Autor:
Robert Kraft, Allon Kahn, José L. Medina-Franco, Mikayla L. Orlowski, Cayla Baynes, Fabian López-Vallejo, Kobus Barnard, Gerald M. Maggiora, Linda L. Restifo
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 217-235 (2013)
SUMMARY The actin-bundling protein fascin is a key mediator of tumor invasion and metastasis and its activity drives filopodia formation, cell-shape changes and cell migration. Small-molecule inhibitors of fascin block tumor metastasis in animal mode
Externí odkaz:
https://doaj.org/article/6dcc206b5f884de0935effbcba21cb6f
Publikováno v:
Revista Colombiana de Ciencias Químico-Farmacéuticas. 50
Introducción: la enfermedad de Chagas es endémica de las zonas tropicales de América Latina y presenta una importante prevalencia, sin embargo, existen pocos tratamientos disponibles en el mercado por lo que la búsqueda de moléculas con potencia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c82b890733fc080655a70028da13b1
https://doi.org/10.15446/rcciquifa.v50n3.91662
https://doi.org/10.15446/rcciquifa.v50n3.91662
Autor:
Freddy A. Ramos, Luzineide W. Tinoco, Abel M. Forero, Alviclér Magalhães, Adrián G. Sandoval-Hernández, Fabian López-Vallejo, Leonardo Castellanos
Publikováno v:
Chemical biologydrug designREFERENCES. 98(4)
Among the compounds of natural origin, diterpenes have proved useful as drugs for the treatment of cancer. Marine organisms, such as soft corals and algae, are a promising source of diterpenes, being a rich and unexplored source of cytotoxic agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7241d223f7ccda14173c34a384376d0
https://pubmed.ncbi.nlm.nih.gov/34143939
https://pubmed.ncbi.nlm.nih.gov/34143939
Publikováno v:
Chemical Biology & Drug Design. 90:175-187
Tuberculosis (TB) is one of the most important public health problems around the world. The emergence of multi-drug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains has driven the finding of alternative anti-TB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0231ad5366bca182839d3202bb0c36
https://doi.org/10.1111/cbdd.12950
https://doi.org/10.1111/cbdd.12950
Autor:
David Ramírez, Carlos Y. Soto, Dulce Mata Espinosa, Julio Caballero, Fabian López-Vallejo, Rogelio Hernández-Pando, Paola Santos
Publikováno v:
Bioorganicmedicinal chemistry. 28(3)
The emergence of tuberculosis (TB) produced by multi-drug resistance (MDR) and extensively-drug resistance (XDR) Mycobacterium tuberculosis (Mtb), encourages the development of new antituberculous compounds, as well as the identification of novel dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77be33e206d16d296a90df84d0c51478
https://pubmed.ncbi.nlm.nih.gov/31879181
https://pubmed.ncbi.nlm.nih.gov/31879181
Autor:
Marco Coazzoli, Gonzalo Arboleda, Adrián G. Sandoval-Hernández, Fabian López-Vallejo, Martina Brucoli, Diego Muñoz, Wilman A. Delgado, Emilio Clementi, Luis E. Cuca, Silvia Zecchini, Elisabetta Catalani, Matteo Giovarelli, Clara De Palma, Davide Cervia, Cristiana Perrotta
Publikováno v:
Cancers
Volume 11
Issue 9
Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Cancers, Vol 11, Iss 9, p 1336 (2019)
Volume 11
Issue 9
Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Cancers, Vol 11, Iss 9, p 1336 (2019)
X-linked inhibitor of apoptosis protein (XIAP) is an emerging crucial therapeutic target in cancer. We report on the discovery and characterisation of small organic molecules from Piper genus plants exhibiting XIAP antagonism, namely erioquinol, a qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cc48a32c2a99d5c88bbd24b9bce153
http://europepmc.org/articles/PMC6770071
http://europepmc.org/articles/PMC6770071
Autor:
Fabian López-Vallejo, Catrin Y. Mendoza-Valencia, Daniel Trespalacios Rodríguez, Diana Jazmín Mariño Gaviria, Álvaro Emilio Sarmiento Gutiérrez, Nancy Patiño Reyes
Publikováno v:
Forensic science international. 304
The new psychoactive substances (NPS) in Colombia are detected by national authorities, in blotters strip, in different circumstances and places: airports, music concerts, discos and parks. Blotters are marketed as LSD and cause several cases of into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95cef1fce74aa52e4715506428965c6
https://pubmed.ncbi.nlm.nih.gov/31593907
https://pubmed.ncbi.nlm.nih.gov/31593907
Autor:
Andres Quintanar-Setephano, Laura C. Berumen, Fabian López-Vallejo, Guadalupe García-Alcocer, Karla Padilla, Ricardo Miledi
Publikováno v:
Brain and Behavior
Background Major depressive disorders are characterized by their severity and long‐lasting symptoms, which make such disorders highly disabling illnesses. Unfortunately, 50% of major depressive patients experience relapses, perhaps partly because d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb220e758edf4401646d23da782476c1
http://europepmc.org/articles/PMC5943772
http://europepmc.org/articles/PMC5943772
Autor:
Fabian López-Vallejo, Gabriel Navarrete-Vázquez, Maria Guadalupe Morales-Vilchis, Ismael León-Rivera, Hugo Tlahuext, Scott P. Webster, Rolffy Ortiz-Andrade, Hermenegilda Moreno-Diaz, Sergio Hidalgo-Figueroa, Samuel Estrada-Soto, Margaret Binnie, José L. Medina-Franco, Carlos Nava-Zuazo, Juan José Ramírez-Espinosa
Publikováno v:
European Journal of Medicinal Chemistry. 74:179-186
Compounds 1-10 were designed using a bioisosteric approach and were prepared using a short synthetic route. The in vitro inhibitory activity of the compounds against 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) was evaluated. Compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3df06bcaff86973f26eba409eca21f
https://doi.org/10.1016/j.ejmech.2013.12.042
https://doi.org/10.1016/j.ejmech.2013.12.042