Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fabian Kügler"'
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 470-486 (2014)
Substituted phenylpiperazines are often neuropharmacologically active compounds and in many cases are essential pharmacophores of neuroligands for different receptors such as D2-like dopaminergic, serotoninergic and other receptors. Nucleophilic, no-
Externí odkaz:
https://doaj.org/article/126640cd34de49569df08967981a4abc
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:609-618
The D4 receptor is of high interest for research and clinical application but puts high demands on appropriate radioligands to be useful tools for investigation. Search for adequate radioligands suitable for in vivo imaging is therefore still in prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd5b5f34b88d9060cb70e5659b5017d1
https://doi.org/10.1002/jlcr.3074
https://doi.org/10.1002/jlcr.3074
Autor:
Heinz H. Coenen, Johannes Ermert, Marie Brandt, Fabian Kügler, Jens Cardinale, Andreas Helfer
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:450-453
A recently published palladium-catalyzed preparation of fluoroarenes starting from caesium fluoride attracted interest as a new alternative for radiofluorination. To test this method, a suitable protocol for the synthesis of 4-[18F]fluorotoluene and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90dd2cb26f2055b49fc210a76b07114a
https://doi.org/10.1002/jlcr.2973
https://doi.org/10.1002/jlcr.2973
Autor:
Fabian, Kügler, Daniel, Roehrens, Milosch, Stumpf, Christian, Drerup, Johannes, Ermert, Kurt, Hamacher, Heinz H, Coenen
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 91
The effect of varying structural modifications of carbon anodes, ranging from thin layers of crystalline boron-doped diamond up to highly graphitic bulk materials, was systematically examined for the possibility of electrochemical fixation and desorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb266ef0aff92434cb3e162719544776
https://pubmed.ncbi.nlm.nih.gov/24880527
https://pubmed.ncbi.nlm.nih.gov/24880527
Autor:
Wiebke Sihver, Heinz H. Coenen, Harald Hübner, Olaf Prante, Peter Gmeiner, Johannes Ermert, Fabian Kügler
Publikováno v:
Journal of medicinal chemistry. 54(24)
Derivatization of the putative neuroleptic 1-(2,3-dihydrobenzo[1,4]dioxin-6-yl)-4-(4-fluorobenzyl)piperazine (3a) led to a series of new dopamine receptor D4 ligands displaying high affinity (Ki=1.1-15 nM) and D2/D4 subtype selectivities of about 800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0335ed2aaf684c72a0e428bd677f587
https://pubmed.ncbi.nlm.nih.gov/22039961
https://pubmed.ncbi.nlm.nih.gov/22039961