Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Fabian Hiller"'
Autor:
Daniel Merk, Sridhar Sreeramulu, Denis Kudlinzki, Krishna Saxena, Verena Linhard, Santosh L. Gande, Fabian Hiller, Christina Lamers, Ewa Nilsson, Anna Aagaard, Lisa Wissler, Niek Dekker, Krister Bamberg, Manfred Schubert-Zsilavecz, Harald Schwalbe
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The ligand-activated transcription factor farnesoid X receptor (FXR) acts as a cellular sensor for bile acids and is of interest as a drug target. Here the authors employ X-ray crystallography and NMR to characterize the molecular determinants of FXR
Externí odkaz:
https://doaj.org/article/6e7a5ba2682343c4b07e17fc173490a6
Autor:
Hannah Steinert, Florian Sochor, Anna Wacker, Janina Buck, Christina Helmling, Fabian Hiller, Sara Keyhani, Jonas Noeske, Steffen Grimm, Martin M Rudolph, Heiko Keller, Rachel Anne Mooney, Robert Landick, Beatrix Suess, Boris Fürtig, Jens Wöhnert, Harald Schwalbe
Publikováno v:
eLife, Vol 6 (2017)
In bacteria, the regulation of gene expression by cis-acting transcriptional riboswitches located in the 5'-untranslated regions of messenger RNA requires the temporal synchronization of RNA synthesis and ligand binding-dependent conformational refol
Externí odkaz:
https://doaj.org/article/9ca65ffa9a5e4f31902497f97157d4fa
Autor:
Fabian Hiller, Christina Lamers, Santosh Lakshmi Gande, Sridhar Sreeramulu, Anna Aagaard, Lisa Wissler, Verena Linhard, Krister Bamberg, Denis Kudlinzki, Krishna Saxena, Ewa Nilsson, Harald Schwalbe, Manfred Schubert-Zsilavecz, Niek Dekker, Daniel Merk
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
The bile acid-sensing transcription factor farnesoid X receptor (FXR) regulates multiple metabolic processes. Modulation of FXR is desired to overcome several metabolic pathologies but pharmacological administration of full FXR agonists has been plag
Autor:
Anna Wacker, Julia E Weigand, Sabine R Akabayov, Nadide Altincekic, Jasleen Kaur Bains, Elnaz Banijamali, Oliver Binas, Jesus Castillo-Martinez, Erhan Cetiner, Betül Ceylan, Liang-Yuan Chiu, Jesse Davila-Calderon, Karthikeyan Dhamotharan, Elke Duchardt-Ferner, Jan Ferner, Lucio Frydman, Boris Fürtig, José Gallego, J Tassilo Grün, Carolin Hacker, Christina Haddad, Martin Hähnke, Martin Hengesbach, Fabian Hiller, Katharina F Hohmann, Daniel Hymon, Vanessa de Jesus, Henry Jonker, Heiko Keller, Bozana Knezic, Tom Landgraf, Frank Löhr, Le Luo, Klara R Mertinkus, Christina Muhs, Mihajlo Novakovic, Andreas Oxenfarth, Martina Palomino-Schätzlein, Katja Petzold, Stephen A Peter, Dennis J Pyper, Nusrat S Qureshi, Magdalena Riad, Christian Richter, Krishna Saxena, Tatjana Schamber, Tali Scherf, Judith Schlagnitweit, Andreas Schlundt, Robbin Schnieders, Harald Schwalbe, Alvaro Simba-Lahuasi, Sridhar Sreeramulu, Elke Stirnal, Alexey Sudakov, Jan-Niklas Tants, Blanton S Tolbert, Jennifer Vögele, Lena Weiß, Julia Wirmer-Bartoschek, Maria A Wirtz Martin, Jens Wöhnert, Heidi Zetzsche
Publikováno v:
Nucleic Acids Research
The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2) highlights the need for coordinated research to combat COVID-19. A particularly important aspect is the development of medication. In addition to viral proteins, structur
Autor:
Boris Fürtig, Rachel A. Mooney, Beatrix Suess, Hannah Steinert, Christina Helmling, Fabian Hiller, Martin Rudolph, Janina Buck, Anna Wacker, Florian Sochor, Harald Schwalbe, Jonas Noeske, Robert Landick, Jens Wöhnert, Steffen Grimm, Sara Keyhani, Heiko Keller
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
In bacteria, the regulation of gene expression by cis-acting transcriptional riboswitches located in the 5'-untranslated regions of messenger RNA requires the temporal synchronization of RNA synthesis and ligand binding-dependent conformational refol
Autor:
Fabian Hiller, Rachel A. Mooney, Heiko Keller, Jens Wöhnert, Martin Rudolph, Steffen Grimm, Sara Keyhani, Robert Landick, Janina Buck, Hannah Steinert, Christina Helmling, Boris Fürtig, Florian Sochor, Jonas Noeske, Anna Wacker, Beatrix Suess, Harald Schwalbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1b540f6f6002b0b3cd3bff50860012
https://doi.org/10.7554/elife.21297.018
https://doi.org/10.7554/elife.21297.018
Autor:
Fabian Hiller, Sascha Baumann, Hendrik R. A. Jonker, Kathrin W. Schulte, Hans-Dieter Arndt, Harald Schwalbe, Sebastian Schoof, Antje Wolf, Karl N. Kirschner
Publikováno v:
Angewandte Chemie. 123:3366-3370
Autor:
Sebastian Schoof, Hans-Dieter Arndt, Fabian Hiller, Harald Schwalbe, Karl N. Kirschner, Hendrik R. A. Jonker, Sascha Baumann, Kathrin W. Schulte, Antje Wolf
Publikováno v:
Angewandte Chemie International Edition. 50:3308-3312