Výsledky vyhledávání - "Fabian Heisig"

Review of Post-Marketing Safety Data on Tapentadol, a Centrally Acting Analgesic

Autor: Detlef von Zabern, Christian Elling, Melanie Sohns, Fabian Heisig, Ariane Stollenwerk

Publikováno v: Advances in Therapy

Introduction Tapentadol is a centrally acting analgesic that has been available for the management of acute and chronic pain in routine clinical practice since 2009. Methods This is the first integrated descriptive analysis of post-marketing safety d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9267fc1230a23aef38b72645290a6dc7
https://pubmed.ncbi.nlm.nih.gov/29270779

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Long-term Safety and Efficacy of Tapentadol Extended Release Following up to 2 Years of Treatment in Patients With Moderate to Severe, Chronic Pain: Results of an Open-label Extension Trial

Autor: C. Rauschkolb, Stephen A. Rappaport, Robert Buynak, Kevin Rod, Fabian Heisig, Pierre Arsenault, Mila Etropolski

Publikováno v: Clinical therapeutics. 37(11)

Purpose Tapentadol extended release (ER) has demonstrated efficacy and safety for the management of moderate to severe, chronic pain in adults. This study evaluated the long-term safety and tolerability of tapentadol ER in patients with chronic osteo

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https://pubmed.ncbi.nlm.nih.gov/26428249

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Synthesis of BODIPY derivatives substituted with various bioconjugatable linker groups: a construction kit for fluorescent labeling of receptor ligands

Autor: Christa E. Müller, Ali El-Tayeb, Jamshed Iqbal, Fabian Heisig, S. J. Freudenthal, Sabrina Gollos

Publikováno v: Journal of fluorescence. 24(1)

The goal of the present study was to design small, functionalized green-emitting BODIPY dyes, which can readily be coupled to target molecules such as receptor ligands, or even be integrated into their pharmacophores. A simple two-step one-pot proced

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https://pubmed.ncbi.nlm.nih.gov/24052460

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Bispidines for Dual Imaging

Autor: Jennifer K. Molloy, Paola Ceroni, Christa E. Müller, Fabian Heisig, Silke Fähnemann, Peter Comba, Holger Stephan, Werner Kraus, Giacomo Bergamini, Martin Walther

Publikováno v: ResearcherID
Chemistry-A European Journal 20(2014), 17011-17018

The efficient transformation of the hexadentate bispidinol 1 into carbamate derivatives yields functional bispidines for the convenient functionalization for targeted imaging. The BODIPY-substituted bispidine 3 combines the coordination site for meta

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http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=CCC&KeyUT=CCC:000346056600024&KeyUID=CCC:000346056600024