Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fabian Guggenberger"'
Autor:
Gertrud E. Feiersinger, Kristina Trattnig, Peter D. Leitner, Fabian Guggenberger, Alexander Oberhuber, Sarah Peer, Martin Hermann, Ira Skvortsova, Jana Vrbkova, Jan Bouchal, Zoran Culig, Frédéric R. Santer
Publikováno v:
Molecular Oncology, Vol 12, Iss 4, Pp 561-576 (2018)
A number of prostate cancer (PCa)‐specific genomic aberrations (denominated BRCAness genes) have been discovered implicating sensitivity to PARP inhibition within the concept of synthetic lethality. Recent clinical studies show favorable results fo
Externí odkaz:
https://doaj.org/article/d6ce9ba31a4a4172989bdef9eb2f89e3
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
Canonical activation of the AR (by R1881) and of STAT3 (by IL6) are rapid processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b08085bc5ac3499c6ab8401e340cfa4
https://doi.org/10.1158/1535-7163.22504522
https://doi.org/10.1158/1535-7163.22504522
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
IL6/STAT3 signaling is associated with endocrine therapy resistance in prostate cancer, but therapies targeting this pathway in prostate cancer were unsuccessful in clinical trials so far. The mechanistic explanation for this phenomenon is currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d1d48a3c096b978cdd814264163248
https://doi.org/10.1158/1535-7163.c.6537760
https://doi.org/10.1158/1535-7163.c.6537760
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
The GR is expressed in some of the used cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc4a8fe43c086946990ab95a91767dd
https://doi.org/10.1158/1535-7163.22504516
https://doi.org/10.1158/1535-7163.22504516
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
The STAT3 inhibitor galiellalactone inhibits the transcriptional activity of STAT3 without reducing its phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50eda77911ef0014e5d5a99cb574aa1c
https://doi.org/10.1158/1535-7163.22504519
https://doi.org/10.1158/1535-7163.22504519
Autor:
Zoran Culig, Holger H.H. Erb, Frank Claessens, Wytske M. van Weerden, Rute B. Marques, Frédéric R. Santer, Fabian Guggenberger, Martina Gruber, Julia Hoefer, Nicla Lorito, Georg Schaefer, Martin Puhr, Florian Handle
Response to galiellalactone is not determined by the basal expression level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024cc096333c5ff9b4fba60c1969f2fe
https://doi.org/10.1158/1535-7163.22504513.v1
https://doi.org/10.1158/1535-7163.22504513.v1
Autor:
Georg Schäfer, Sarah Peer, Frédéric R. Santer, G. Jenster, Holger H.H. Erb, Fabian Guggenberger, Giuseppe Cappellano, Ira Skvortsova, Harmen J.G. van de Werken, Zoran Culig, Florian Handle, Kristina Trattnig
Publikováno v:
European Urology, 74(6), 847-849. Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd25c9a3fe5fcd3a714bc48d75994114
https://doi.org/10.1016/j.eururo.2018.06.002
https://doi.org/10.1016/j.eururo.2018.06.002
Autor:
Rute B. Marques, Holger H.H. Erb, Zoran Culig, Georg Schaefer, Martin Puhr, Fabian Guggenberger, Julia Hoefer, Nicla Lorito, Frédéric R. Santer, Frank Claessens, Wytske M. van Weerden, Florian Handle, Martina Gruber
Publikováno v:
Molecular Cancer Therapeutics, 17(12), 2722-2731. American Association for Cancer Research Inc.
IL6/STAT3 signaling is associated with endocrine therapy resistance in prostate cancer, but therapies targeting this pathway in prostate cancer were unsuccessful in clinical trials so far. The mechanistic explanation for this phenomenon is currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a544746538598470626df199b7b36ed
https://pure.eur.nl/en/publications/a82fbe6b-1e16-478a-acbc-366a9bb6f095
https://pure.eur.nl/en/publications/a82fbe6b-1e16-478a-acbc-366a9bb6f095
Publikováno v:
Journal of Cellular Biochemistry
Pro‐ and anti‐inflammatory cytokines may influence proliferation, migration, invasion, and other cellular events of prostate cancer (PCa) cells. The hyaluronan receptor CD44, which is regulated by Interleukin (IL)‐4, is a prostate basal cell ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::372f5239001795b6bef8cdfbc0527c91
https://pubmed.ncbi.nlm.nih.gov/29236307
https://pubmed.ncbi.nlm.nih.gov/29236307
Autor:
G. Stecher, Jan Barthelmes, Fabian Guggenberger, Reinhold Ramoner, Daniel Intelmann, Natalie Sampson, G. Abel, Helmut Klocker, Andrea Dueregger, Markus Schuh, Jutta Haunschild
Publikováno v:
Phytomedicine. 20:1306-1314
This study aimed to investigate the mechanisms underlying the anti-proliferative effects of the ethanolic Cimicifuga racemosa extract BNO-1055 on prostate cells and evaluate its therapeutic potential. BNO-1055 dose-dependently attenuated cellular upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cfad36e8c460fa09ae80ad277559b3
https://doi.org/10.1016/j.phymed.2013.07.009
https://doi.org/10.1016/j.phymed.2013.07.009