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pro vyhledávání: '"Fabian Fey"'
Publikováno v:
European Journal of Immunology. 38:1689-1699
The upper airways are prone to contact with pathogenic as well as non-pathogenic microbes, therefore immune recognition principles have to be tightly controlled. Here we show that human BEAS-2B bronchial epithelial cells inhibited secretion of the pr
Autor:
Karl-Heinz Altmann, Frédéric Cachoux, Fabian Feyen, Jürg Gertsch, Christian N. Kuzniewski, Markus Wartmann
Publikováno v:
CHIMIA, Vol 64, Iss 1-2 (2010)
Epothilones are bacterial macrolides with potent microtubule-stabilizing and antiproliferative activity, which have served as successful lead structures for the discovery of several clinical candidates for cancer treatment. Overall, seven epothilone-
Externí odkaz:
https://doaj.org/article/8768fba7639648829d95c17e1b19899f
Publikováno v:
CHIMIA, Vol 61, Iss 4 (2007)
12-Aza-epothilones ('Azathilones') 1 and 2 have been prepared through ring-closing olefin metathesis or macrolactonization-based cyclization reactions. While RCM of the respective dienes 9 and 12 was found to be very effective and produced macrocycli
Externí odkaz:
https://doaj.org/article/c5cc4b581d184b11b03a937babf5385e