Regulation of plasmalogen metabolism and traffic in mammals: The fog begins to lift

Autor: Fabian Dorninger, Ernst R. Werner, Johannes Berger, Katrin Watschinger

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Due to their unique chemical structure, plasmalogens do not only exhibit distinct biophysical and biochemical features, but require specialized pathways of biosynthesis and metabolization. Recently, major advances have been made in our understanding

Externí odkaz: https://doaj.org/article/c393d7b3093d4812beadd03c238563f7

Nestlet Shredding and Nest Building Tests to Assess Features of Psychiatric Disorders in Mice

Autor: Fabian Dorninger, Gerhard Zeitler, Johannes Berger

Publikováno v: Bio-Protocol, Vol 10, Iss 24 (2020)

Mimicking the various facets of human psychiatric and neurodevelopmental disorders in animal models is a challenging task. Nevertheless, mice have emerged as a widely used model system to study pathophysiology and treatment strategies for these disea

Externí odkaz: https://doaj.org/article/d311ca92a5204893bdeaa21e9fc17c13

Overlapping and Distinct Features of Cardiac Pathology in Inherited Human and Murine Ether Lipid Deficiency

Autor: Fabian Dorninger, Attila Kiss, Peter Rothauer, Alexander Stiglbauer-Tscholakoff, Stefan Kummer, Wedad Fallatah, Mireia Perera-Gonzalez, Ouafa Hamza, Theresa König, Michael B. Bober, Tiscar Cavallé-Garrido, Nancy E. Braverman, Sonja Forss-Petter, Christian Pifl, Jan Bauer, Reginald E. Bittner, Thomas H. Helbich, Bruno K. Podesser, Hannes Todt, Johannes Berger

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 3; Pages: 1884

Inherited deficiency in ether lipids, a subgroup of glycerophospholipids with unique biochemical and biophysical properties, evokes severe symptoms in humans resulting in a multi-organ syndrome. Mouse models with defects in ether lipid biosynthesis h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227d5d63e14c4d16cb1fff7a4228d123

Ether lipid transfer across the blood-brain and placental barriers does not improve by inactivation of the most abundant ABC transporters

Autor: Fabian Dorninger, Frédéric M. Vaz, Hans R. Waterham, Jan B. van Klinken, Gerhard Zeitler, Sonja Forss-Petter, Johannes Berger, Christoph Wiesinger

Publikováno v: Brain Research Bulletin, 189, 69-79. Elsevier Inc.
Dorninger, F, Vaz, F M, Waterham, H R, Klinken, J B V, Zeitler, G, Forss-Petter, S, Berger, J & Wiesinger, C 2022, ' Ether lipid transfer across the blood-brain and placental barriers does not improve by inactivation of the most abundant ABC transporters ', Brain Research Bulletin, vol. 189, pp. 69-79 . https://doi.org/10.1016/j.brainresbull.2022.08.006
Brain Research Bulletin, 189, 69-79. PERGAMON-ELSEVIER SCIENCE LTD
Brain research bulletin, 189, 69-79. Elsevier Inc.

Phospholipid transport from the periphery to the brain is an understudied topic. When certain lipid species are deficient due to impaired synthesis, though, transfer across the blood-brain barrier is essential for replenishing lipids in the brain. Fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2331d5f844cc7de77f5bf1c351dca1
https://pubmed.ncbi.nlm.nih.gov/35981629

A

Autor: Wedad, Fallatah, Wei, Cui, Erminia, Di Pietro, Grace T, Carter, Brittany, Pounder, Fabian, Dorninger, Christian, Pifl, Ann B, Moser, Johannes, Berger, Nancy E, Braverman

Publikováno v: Frontiers in cell and developmental biology. 10

Rhizomelic chondrodysplasia punctata type 1 (RCDP1) is a peroxisome biogenesis disorder caused by defects in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5c34bfb1efd29a51f934f8ea457de55
https://pubmed.ncbi.nlm.nih.gov/35898397