Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Fabian Docagne"'
Tissue-plasminogen activator effects on the phenotype of splenic myeloid cells in acute inflammation
Autor:
Célia Seillier, Léonie Lesec, Pauline Hélie, Charlotte Marie, Denis Vivien, Fabian Docagne, Brigitte Le Mauff, Olivier Toutirais
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Tissue-plasminogen activator (tPA) is a serine protease well known for its fibrinolytic function. Recent studies indicate that tPA could also modulate inflammation via plasmin generation and/or by receptor mediated signalling in vitro. Howev
Externí odkaz:
https://doaj.org/article/112f53425753441187043f14f6d731cd
Autor:
Pauline Hélie, Celia Camacho-Toledano, Léonie Lesec, Célia Seillier, Antonio J. Miralles, Maria Cristina Ortega, Sylvaine Guérit, Héloïse Lebas, Isabelle Bardou, Virginia Vila-del Sol, Denis Vivien, Brigitte Le Mauff, Diego Clemente, Fabian Docagne, Olivier Toutirais
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Tissue plasminogen activator (tPA) is a serine protease involved in fibrinolysis. It is released by endothelial cells, but also expressed by neurons and glial cells in the central nervous system (CNS). Interestingly, this enzyme a
Externí odkaz:
https://doaj.org/article/1d3203b23fab4d6ba6cda1c955e10cd7
Autor:
Alexandre Couture, Anthony Garnier, Fabian Docagne, Olivier Boyer, Denis Vivien, Brigitte Le-Mauff, Jean-Baptiste Latouche, Olivier Toutirais
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD4+ T cells differentiate into various T helper subsets characterized by distinct cytokine secreting profiles that confer them effector functions adapted to a variety of infectious or endogenous threats. Regulatory CD4+ T cells are another specializ
Externí odkaz:
https://doaj.org/article/4a1c67bc23984cca9d680fc6d4f65167
Autor:
Daniel Garcia-Ovejero, Angel Arevalo-Martin, Stefania Petrosino, Fabian Docagne, Carlos Hagen, Tiziana Bisogno, Masahiko Watanabe, Carmen Guaza, Vincenzo Di Marzo, Eduardo Molina-Holgado
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 1, Pp 57-71 (2009)
Endocannabinoids are lipid mediators with protective effects in many diseases of the nervous system. We have studied the modulation of the endocannabinoid system after a spinal cord contusion in rats. In early stages, lesion induced increases of anan
Externí odkaz:
https://doaj.org/article/e6b956148c4a4af9a2df2dddaf4abc48
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 3, Pp 638-650 (2006)
The ME7 model of murine prion disease shows an atypical inflammatory response characterized by morphologically activated microglia and an anti-inflammatory cytokine profile with a marked expression of TGFβ1. The investigation of the role of TGFβ1 d
Externí odkaz:
https://doaj.org/article/9086c18ef42b4e899da4443417d2d760
Autor:
Marina Rubio, Hélène Villain, Fabian Docagne, Benoit D Roussel, José Antonio Ramos, Denis Vivien, Javier Fernandez-Ruiz, Carine Ali
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23690 (2011)
Cessation of chronic ethanol consumption can increase the sensitivity of the brain to excitotoxic damages. Cannabinoids have been proposed as neuroprotectants in different models of neuronal injury, but their effect have never been investigated in a
Externí odkaz:
https://doaj.org/article/39b37eb016e54f48aa54e79f8b3517b6
Autor:
Héloïse Lebas, Sylvaine Guérit, Audrey Picot, Anne Cécile Boulay, Antoine Fournier, Denis Vivien, Martine Cohen Salmon, Fabian Docagne, Isabelle Bardou
Publikováno v:
Cellular and Molecular Life Sciences. 79
In multiple sclerosis (MS), disturbance of the plasminogen activation system (PAS) and blood brain barrier (BBB) disruption are physiopathological processes that might lead to an abnormal fibrin(ogen) extravasation into the parenchyma. Fibrin(ogen) d
Autor:
Léonie Lesec, Olivier Etard, Richard Macrez, Eric Maubert, Brigitte Le-Mauff, Jérôme Leprince, Véronique Agin, Fabian Docagne, Isabelle Wagnon, Pauline Hélie, Barbara Delaunay, Olivier Toutirais, Denis Vivien, Isabelle Bardou, Mikaël Naveau, Caroline Regnauld
Publikováno v:
Brain. 143:2957-2972
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a neuropsychiatric disease characterized by an antibody-mediated autoimmune response against NMDAR. Recent studies have shown that anti-NMDAR antibodies are involved in the pathophysiology of
Autor:
Fabian Docagne, Pauline Hélie, Olivier Toutirais, Célia Seillier, Brigitte Le Mauff, Gautier Petit, Denis Vivien, Diego Clemente
Publikováno v:
Cellular Immunology
The COVID-19 pandemic has once again brought to the forefront the existence of a tight link between the coagulation/fibrinolytic system and the immunologic processes. Tissue-type plasminogen activator (tPA) is a serine protease with a key role in fib
Autor:
Sara Martinez de Lizarrondo, Carine Ali, Marina Rubio, Tiziana Crepaldi, Maxime Gauberti, Fabian Docagne, Eugénie Garnier, Izaskun Buendia, Damien Levard, Paolo M. Comoglio, Yannick Hommet, Denis Vivien
Background Factor XII (FXII) is a serine protease that participates in the intrinsic coagulation pathway. Several studies have shown that plasma FXII exerts a deleterious role in cerebral ischemia and traumatic brain injury by promoting thrombo-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a99b5b5dce69689a091517e3b7db08
http://hdl.handle.net/2318/1794801
http://hdl.handle.net/2318/1794801