Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fabian Classen"'
Autor:
Mosche Pompsch, Julia Vogel, Fabian Classen, Philip Kranz, George Iliakis, Helena Riffkin, Ulf Brockmeier, Eric Metzen
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The nudix family member enzyme MutT homologue-1 (MTH1) hydrolyses the oxidized nucleotides 8-oxo-dGTP and 2-hydroxy-dATP and thus prevents the incorporation of damaged nucleotides into nuclear and mitochondrial DNA. Therefore MTH1
Externí odkaz:
https://doaj.org/article/8b14a0f6eff5445e891288cc7a4323ad
Autor:
Philip Kranz, Helena Riffkin, Eric Metzen, Alexandra Wolf, Ulf Brockmeier, Fabian Classen, Mosche Pompsch, Kirsten Göpelt, Jennifer Baumann, Melanie Baumann
Publikováno v:
Experimental Cell Research. 374:29-37
Autophagy is commonly described as a cell survival mechanism and has been implicated in chemo- and radioresistance of cancer cells. Whether ionizing radiation induced autophagy triggers tumor cell survival or cell death still remains unclear. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f185b6d522bcce7ea3b923e194ee92
https://doi.org/10.1016/j.yexcr.2018.11.004
https://doi.org/10.1016/j.yexcr.2018.11.004
Autor:
Fabian Classen, George Iliakis, Helena Riffkin, Eric Metzen, Ulf Brockmeier, Julia Vogel, Philip Kranz, Mosche Pompsch
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
BMC Cancer
BMC Cancer
BACKGROUND: The nudix family member enzyme MutT homologue-1 (MTH1) hydrolyses the oxidized nucleotides 8-oxo-dGTP and 2-hydroxy-dATP and thus prevents the incorporation of damaged nucleotides into nuclear and mitochondrial DNA. Therefore MTH1 was pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa1366309b167f9c1c904a2a61416f6
http://link.springer.com/article/10.1186/s12885-018-5095-x
http://link.springer.com/article/10.1186/s12885-018-5095-x
Autor:
Philip Kranz, Tobias Ocklenburg, Ulf Brockmeier, Melanie Baumann, Kirsten Goepelt, Fabian Classen, Fabian Neumann, Alexandra Wolf, Helena Riffkin, Mosche Pompsch, Jennifer Baumann, Kirsten Janke, Eric Metzen
Publikováno v:
Cell Death & Disease
Endoplasmic reticulum (ER) stress leads to activation of the unfolded protein response (UPR) that results in transient suppression of protein translation to allow recovery but leads to cell death when stress cannot be resolved. Central to initiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ead2b31bb7e065c30be31b8bec3bbe3
https://www.ncbi.nlm.nih.gov/pubmed/28796255
https://www.ncbi.nlm.nih.gov/pubmed/28796255
