Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Fabian C Herbert"'
Autor:
Mohamad Ammar Ayass, Trivendra Tripathi, Natalya Griko, Victor Pashkov, Jun Dai, Jin Zhang, Fabian C. Herbert, Ramya Ramankutty Nair, Tutku Okyay, Kevin Zhu, Jeremiah J. Gassensmith, Lina Abi-Mosleh
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background The paucity of SARS-CoV-2-specific virulence factors has greatly hampered the therapeutic management of patients with COVID-19 disease. Although available vaccines and approved therapies have shown tremendous benefits, the continu
Externí odkaz:
https://doaj.org/article/31524c5489f54663a03c1738ff62c20b
Autor:
Jenica L. Lumata, Darby Ball, Arezoo Shahrivarkevishahi, Michael A. Luzuriaga, Fabian C. Herbert, Olivia Brohlin, Hamilton Lee, Laurel M. Hagge, Sheena D’Arcy, Jeremiah J. Gassensmith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Virus-like particles are an emerging class of nano-biotechnology with the Tobacco Mosaic Virus (TMV) having found a wide range of applications in imaging, drug delivery, and vaccine development. TMV is typically produced in planta, and, as a
Externí odkaz:
https://doaj.org/article/d69d7ca991e7467d9ab0800e5535d8db
Autor:
Fabian C. Herbert, Sameera S. Abeyrathna, Nisansala S. Abeyrathna, Yalini H. Wijesundara, Olivia R. Brohlin, Francesco Carraro, Heinz Amenitsch, Paolo Falcaro, Michael A. Luzuriaga, Alejandra Durand-Silva, Shashini D. Diwakara, Ronald A. Smaldone, Gabriele Meloni, Jeremiah J. Gassensmith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Stabilizing lipid nanoparticles and lipidprotein assemblies is challenging owing to lipid dynamics and protein instability. Here, the authors report on the reversible encapsulation of liposomes and proteoliposomes in a metalorganic framework permitti
Externí odkaz:
https://doaj.org/article/6c63006885b6455ba0e68e5b925e37f0
Self-assembly of a fluorescent virus-like particle for imaging in tissues with high autofluorescence
Autor:
Ikeda Trashi, Mateusz Z. Durbacz, Orikeda Trashi, Yalini H. Wijesundara, Ryanne N. Ehrman, Alyssa C. Chiev, Cary B. Darwin, Fabian C. Herbert, Jashkaran Gadhvi, Nicole J. De Nisco, Steven O. Nielsen, Jeremiah J. Gassensmith
Publikováno v:
Journal of Materials Chemistry B. 11:4445-4452
Qβ VLP simplified assembly approach uses the positively charged Rev tag to interact electrostatically with the negatively charged RNAs. This system exploits the known hairpins produced in the coat protein sequence to template the assembly of the ful
Autor:
Yalini H. Wijesundara, Fabian C. Herbert, Sneha Kumari, Thomas Howlett, Shailendra Koirala, Orikeda Trashi, Ikeda Trashi, Noora M. Al-Kharji, Jeremiah J. Gassensmith
Publikováno v:
Virology. 577:105-123
Viruses are some of nature's most ubiquitous self-assembled molecular containers. Evolutionary pressures have created some incredibly robust, thermally, and enzymatically resistant carriers to transport delicate genetic information safely. Virus-like
Autor:
Sneha Kumari, Yalini H. Wijesundara, Thomas S. Howlett, Mohammad Waliullah, Fabian C. Herbert, Arun Raja, Ikeda Trashi, Rodrigo A. Bernal, Jeremiah J. Gassensmith
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Needle-and-syringe-based delivery has been the commercial standard for vaccine administration to date. With worsening medical personnel availability, increasing biohazard waste production, and the possibility of cross-contamination, we explore the po
Autor:
Yalini H. Wijesundara, Fabian C. Herbert, Orikeda Trashi, Ikeda Trashi, Olivia R. Brohlin, Sneha Kumari, Thomas Howlett, Candace E. Benjamin, Arezoo Shahrivarkevishahi, Shashini D. Diwakara, Sachini D. Perera, Samuel A. Cornelius, Juan P. Vizuet, Kenneth J. Balkus, Ronald A. Smaldone, Nicole J. De Nisco, Jeremiah J. Gassensmith
Publikováno v:
Chemical Science. 13:13803-13814
The efficacy and specificity of protein, DNA, and RNA-based drugs have made them popular in the clinic; however, their susceptibility to environmental stressors adds significant challenges to formulating biomacromolecules into delivery systems where
Autor:
Shashini D. Diwakara, Whitney S. Y. Ong, Yalini H. Wijesundara, Robert L. Gearhart, Fabian C. Herbert, Sarah G. Fisher, Gregory T. McCandless, Sampath B. Alahakoon, Jeremiah J. Gassensmith, Sheel C. Dodani, Ronald A. Smaldone
Publikováno v:
J Am Chem Soc
Two-dimensional covalent organic frameworks (2D-COFs) are a class of crystalline porous organic polymers that consist of covalently linked, two-dimensional sheets that can stack together through noncovalent interactions. Here we report the synthesis
Autor:
Jashkaran Gadhvi, Olivia R. Brohlin, Hamilton Lee, Jeremiah J. Gassensmith, Alisia C. Tumac, Nicole J. De Nisco, Yalini H. Wijesundara, Michael A. Luzuriaga, Fabian C. Herbert, Abhinay V. Adlooru, Perouza Parsamian, Arezoo Shahrivarkevishahi, Candace E. Benjamin
Publikováno v:
Journal of the American Chemical Society. 143:16428-16438
Virus-like particles (VLPs) are multifunctional nanocarriers that mimic the architecture of viruses. They can serve as a safe platform for specific functionalization and immunization, which provides benefits in a wide range of biomedical applications
Autor:
Sundharamani Venkitapathi, Yalini H. Wijesundara, Samuel A. Cornelius, Fabian C. Herbert, Jeremiah J. Gassensmith, Philippe E. Zimmern, Nicole J. De Nisco
Publikováno v:
Journal of Bacteriology. 204
Klebsiella spp. commonly cause both uncomplicated urinary tract infection (UTI) and recurrent UTI (rUTI). Klebsiella quasipneumoniae, a relatively newly defined species of Klebsiella, has been shown to be metabolically distinct from Klebsiella pneumo