Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Fabian Baltes"'
Autor:
Sven Marcel Stefan, Jiyang Li, Gerd Bendas, Vigneshwaran Namasivayam, Fabian Baltes, Katja Silbermann, Michael Wiese
Publikováno v:
Journal of Medicinal Chemistry. 63:10412-10432
In the search for highly effective modulators addressing ABCG2-mediated MDR, 23 pyrimidines were synthesized and biologically assessed. Seven derivatives with (a) nitrogen- and/or halogen-containing residue(s) had extraordinary potencies against ABCG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce264c4353ccafe77f7d33d9470e11d
https://doi.org/10.1021/acs.jmedchem.0c00961
https://doi.org/10.1021/acs.jmedchem.0c00961
Autor:
Lukas M. Gockel, Vladlena Pfeifer, Fabian Baltes, Rafael D. Bachmaier, Karl G. Wagner, Gerd Bendas, Michael Gütschow, Izidor Sosič, Christian Steinebach
Publikováno v:
Archiv der PharmazieREFERENCES. 355(5)
Although the androgen receptor (AR) is a validated target for the treatment of prostate cancer, resistance to antiandrogens necessitates the development of new therapeutic modalities. Exploiting the ubiquitin-proteasome system with proteolysis-target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3cc2748f9b88e565644b191e6181a6f
https://pubmed.ncbi.nlm.nih.gov/35128717
https://pubmed.ncbi.nlm.nih.gov/35128717
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4956, p 4956 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences
Volume 21
Issue 14
Collagen type 1 (COL1) is a ubiquitously existing extracellular matrix protein whose high density in breast tissue favors metastasis and chemoresistance. COL1-binding of MDA-MB-231 and MCF-7 breast cancer cells is mainly dependent on &beta
1-int
1-int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a905e199b76cdb11dbaed38d1232b9c8
https://www.mdpi.com/1422-0067/21/14/4956
https://www.mdpi.com/1422-0067/21/14/4956
Autor:
Fabian, Baltes, Vladlena, Pfeifer, Katja, Silbermann, Julia, Caspers, Kathleen, Wantoch von Rekowski, Martin, Schlesinger, Gerd, Bendas
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1867(5)
Molecular interactions of tumor cells with the microenvironment are regarded as onset of chemotherapy resistance, referred to as cell adhesion mediated drug resistance (CAM-DR). Here we elucidate a mechanism of CAM-DR in breast cancer cells in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d58beadcd9563e8558ee29462f35282c
https://pubmed.ncbi.nlm.nih.gov/31987794
https://pubmed.ncbi.nlm.nih.gov/31987794
Autor:
Fabian Baltes, Gerd Bendas, Martin Schlesinger, Daniel Bastian Pfankuchen, Jin-Ping Li, Tahira Batool
Publikováno v:
Oncotarget
// Daniel Bastian Pfankuchen 1 , Fabian Baltes 1 , Tahira Batool 2 , Jin-Ping Li 2 , Martin Schlesinger 1 and Gerd Bendas 1 1 Pharmaceutical Institute, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, Germany 2 Department of Medical Biochemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedc09a5cd81eb676d95dce79d56e17d
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-336049
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-336049
Autor:
Fabian Baltes, Gerd Bendas, Martin Schlesinger, Katja Silbermann, Kathleen Wantoch von Rekowski, Julia Caspers, Vladlena Pfeifer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1867:118663
Molecular interactions of tumor cells with the microenvironment are regarded as onset of chemotherapy resistance, referred to as cell adhesion mediated drug resistance (CAM-DR). Here we elucidate a mechanism of CAM-DR in breast cancer cells in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f129c0ec61af9ace319db74811fac7c3
https://doi.org/10.1016/j.bbamcr.2020.118663
https://doi.org/10.1016/j.bbamcr.2020.118663
Publikováno v:
Cancers
Volume 10
Issue 12
Cancers, Vol 10, Iss 12, p 495 (2018)
Volume 10
Issue 12
Cancers, Vol 10, Iss 12, p 495 (2018)
Tumor cell binding to microenvironment components such as collagen type 1 (COL1) attenuates the sensitivity to cytotoxic drugs like cisplatin (CDDP) or mitoxantrone (MX), referred to as cell adhesion mediated drug resistance (CAM-DR). CAM-DR is consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86efeb0cef18c02b81a4c1d8b29ece0
https://pubmed.ncbi.nlm.nih.gov/30563275
https://pubmed.ncbi.nlm.nih.gov/30563275
Autor:
Gockel, Lukas M., Pfeifer, Vladlena, Baltes, Fabian, Bachmaier, Rafael D., Wagner, Karl G., Bendas, Gerd, Gütschow, Michael, Sosič, Izidor, Steinebach, Christian
Publikováno v:
Archiv der Pharmazie; May2022, Vol. 355 Issue 5, p1-15, 15p
Autor:
Baltes, Fabian1 (AUTHOR) fabian-baltes@uni-bonn.de, Caspers, Julia1 (AUTHOR), Henze, Svenja1 (AUTHOR), Schlesinger, Martin1 (AUTHOR), Bendas, Gerd1 (AUTHOR) gbendas@uni-bonn.de
Publikováno v:
International Journal of Molecular Sciences. Jul2020, Vol. 21 Issue 14, p4956. 1p. 7 Graphs.
Autor:
Jakubzig, Bastian1 (AUTHOR), Baltes, Fabian1 (AUTHOR), Henze, Svenja1 (AUTHOR) bastian.jakubzig@uni-bonn.de, Schlesinger, Martin1 (AUTHOR), Bendas, Gerd1 (AUTHOR) gbendas@uni-bonn.de
Publikováno v:
Cancers. Dec2018, Vol. 10 Issue 12, p495. 1p.