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PCB126 Inhibits the Activation of AMPK-CREB Signal Transduction Required for Energy Sensing in Liver
Autor:
Fabian A Sandgruber, Benjamin A Elser, Katherine N. Gibson-Corley, Xueshu Li, Larry W. Robertson, Gopi S. Gadupudi
Publikováno v:
Toxicological Sciences. 163:440-453
3,3′,4,4′,5-pentachlorobiphenyl (PCB126), a dioxin-like PCB, elicits toxicity through a wide array of noncarcinogenic effects, including metabolic syndrome, wasting, and nonalcoholic fatty-liver disease. Previously, we reported decreases in the t