Zobrazeno 1 - 10
of 536
pro vyhledávání: '"Fabian, V."'
Autor:
Filipp, Fabian V.
Spatially annotated single-cell datasets provide unprecedented opportunities to dissect cell-cell communication in development and disease. Heterotypic signaling includes interactions between different cell types and is well established in tissue dev
Externí odkaz:
http://arxiv.org/abs/2303.00933
Quiescence and aging of melanocyte stem cells and a novel association with programmed death-ligand 1
Autor:
Joseph W. Palmer, Kyrene M. Villavicencio, Misgana Idris, Ian J. Baranyk, Nunaya Polycarp, Alex D. Dawson, Dominique Weddle, William J. Pavan, Fabian V. Filipp, Melissa L. Harris
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110908- (2024)
Summary: Cellular quiescence is a reversible and tightly regulated stem cell function essential for healthy aging. However, the elements that control quiescence during aging remain poorly defined. Using melanocyte stem cells (McSCs), we find that ste
Externí odkaz:
https://doaj.org/article/1a31ec8ff6884852991e7733ad925b6f
Quiescence and aging of melanocyte stem cells and a novel association with programmed death-ligand 1
Autor:
Palmer, Joseph W., Villavicencio, Kyrene M., Idris, Misgana, Baranyk, Ian J., Polycarp, Nunaya, Dawson, Alex D., Weddle, Dominique, Pavan, William J., Filipp, Fabian V., Harris, Melissa L.
Publikováno v:
In iScience 18 October 2024 27(10)
The glutamate metabotropic receptor 1 (GRM1) drives oncogenesis when aberrantly activated in melanoma and several other cancers. Metabolomics reveals that patient-derived xenografts with GRM1-positive melanoma tumors exhibit elevated plasma glutamate
Externí odkaz:
http://arxiv.org/abs/1912.07668
Autor:
Filipp, Fabian V.
Machine learning (ML), deep learning (DL), and artificial intelligence (AI) are of increasing importance in biomedicine. The goal of this work is to show progress in ML in digital health, to exemplify future needs and trends, and to identify any esse
Externí odkaz:
http://arxiv.org/abs/1911.07125
Autor:
Box, Neil F., Larue, Lionel, Manga, Prashiela, Montoliu, Lluis, Spritz, Richard A., Filipp, Fabian V.
The International Federation of Pigment Cell Societies (IFPCS) held its XXIII triennial International Pigment Cell Conference (IPCC) in Denver, Colorado in August 2017. The goal of the summit was to provide a venue promoting a vibrant interchange amo
Externí odkaz:
http://arxiv.org/abs/1808.05755
Autor:
Filipp, Fabian V., Birlea, Stanca, Bosenberg, Marcus W., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Poole, Caroline Le, Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S., Box, Neil F.
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact curr
Externí odkaz:
http://arxiv.org/abs/1808.01869
Autor:
Li, Chen, Nguyen, Vincent, Clark, Kaitlyn N., Zahed, Tara, Sharkas, Shawn, Filipp, Fabian V., Boiko, Alexander D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Mar 01. 116(10), 4548-4557.
Externí odkaz:
https://www.jstor.org/stable/26683127
Autor:
Archit Trivedi, Aanchal Mehrotra, Caitlin E. Baum, Brandon Lewis, Tupa Basuroy, Thomas Blomquist, Robert Trumbly, Fabian V. Filipp, Vijayasaradhi Setaluri, Ivana L. de la Serna
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Pharmacologic inhibition of bromodomain and extra-terminal (BET) proteins is currently being explored as a new therapeutic approach in cancer. Some studies have also implicated BET proteins as regulators of cell identity and diffe
Externí odkaz:
https://doaj.org/article/3388d5c1150043a58943b8a9ef32ec3a