Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fabian, Gut"'
Autor:
Mengtian Ren, Fabian Gut, Yilan Fan, Jingke Ma, Xiajing Shan, Aysenur Yikilmazsoy, Mariia Likhodeeva, Karl-Peter Hopfner, Chuanzheng Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Base excision repair (BER) is initialized by DNA glycosylases, which recognize and flip damaged bases out of the DNA duplex into the enzymes active site, followed by cleavage of the glycosidic bond. Recent studies have revealed that all type
Externí odkaz:
https://doaj.org/article/ab826eb8c1d04ac08415a61b311a6343
Autor:
Markus Matthias Hohle, Katja Lammens, Fabian Gut, Bingzhi Wang, Sophia Kahler, Kathrin Kugler, Michael Till, Roland Beckmann, Karl-Peter Hopfner, Christophe Jung
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract While recent technological developments contributed to breakthrough advances in single particle cryo-electron microscopy (cryo-EM), sample preparation remains a significant bottleneck for the structure determination of macromolecular complex
Externí odkaz:
https://doaj.org/article/63856b0cc1234d46a17152757c8a1f1f
Autor:
Fabian, Gut, Lisa, Käshammer, Katja, Lammens, Joseph D, Bartho, Anna-Maria, Boggusch, Erik, van de Logt, Brigitte, Kessler, Karl-Peter, Hopfner
Publikováno v:
Molecular Cell. 82:3513-3522.e6
DNA double-strand breaks (DSBs) threaten genome stability and are linked to tumorigenesis in humans. Repair of DSBs requires the removal of attached proteins and hairpins through a poorly understood but physiologically critical endonuclease activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4252d02c0c76c9906126b2df56e147e4
https://doi.org/10.1016/j.molcel.2022.07.019
https://doi.org/10.1016/j.molcel.2022.07.019
Autor:
Joseph Bartho, Karl-Peter Hopfner, Jan-Hinnerk Saathoff, Brigitte Kessler, Aaron Alt, Fabian Gut, Katja Lammens, Lisa Käshammer
Publikováno v:
Molecular Cell. 76:382-394.e6
Summary DNA double-strand breaks (DSBs) threaten genome stability throughout life and are linked to tumorigenesis in humans. To initiate DSB repair by end joining or homologous recombination, the Mre11-nuclease Rad50-ATPase complex detects and proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc02b128b28ff0f86edabc3b5e6fbd2
https://doi.org/10.1016/j.molcel.2019.07.035
https://doi.org/10.1016/j.molcel.2019.07.035