Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Fabian, Garreis"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4043 (2024)
While the involvement of thermosensitive transient receptor potential channels (TRPs) in dry eye disease (DED) has been known for years, their expression in the meibomian gland (MG) has never been investigated. This study aims to show their expressio
Externí odkaz:
https://doaj.org/article/8973a356dc9841b89cb9a3c8f0b5e983
Autor:
Yuqiuhe Liu, Igor A. Butovich, Fabian Garreis, Ingrid Zahn, Michael Scholz, Simone Gaffling, Samir Jabari, Jana Dietrich, Friedrich Paulsen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3109 (2024)
Meibomian gland dysfunction (MGD) is one of the main causes of dry eye disease. To better understand the physiological functions of human meibomian glands (MGs), the present study compared MGs with free sebaceous glands (SGs) and hair-associated SGs
Externí odkaz:
https://doaj.org/article/c0e9e98a38c94967b0ec7a0f72a3c94f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Posterior lamellar transplantation of the eye’ s cornea (DSAEK, DMEK) currently is the gold standard for treating patients with corneal endothelial cell and back surface pathologies resulting in functional impairment. An artificial biomime
Externí odkaz:
https://doaj.org/article/8f3eea5ac78040f1a0896901f3a44563
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
PurposeDecreased production of the aqueous component of the tear film is an important cause of the development of dry eye disease (DED). Tear production is influenced by hormones and hormone-like factors. Prolactin (PLR), a multifunctional pituitary
Externí odkaz:
https://doaj.org/article/e611a0c60eb54cbeba2d3cef0c962373
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6839 (2023)
Inadequate wound healing of ocular surface injuries can lead to permanent visual impairment. The relaxin ligand-receptor system has been demonstrated to promote corneal wound healing through increased cell migration and modulation of extracellular ma
Externí odkaz:
https://doaj.org/article/6cd4e82d011e4c758398713357de1b46
Autor:
Ulrike Steffen, Carolien A. Koeleman, Maria V. Sokolova, Holger Bang, Arnd Kleyer, Jürgen Rech, Harald Unterweger, Martin Schicht, Fabian Garreis, Jonas Hahn, Fabian T. Andes, Fabian Hartmann, Madelaine Hahn, Aparna Mahajan, Friedrich Paulsen, Markus Hoffmann, Günter Lochnit, Luis E. Muñoz, Manfred Wuhrer, David Falck, Martin Herrmann, Georg Schett
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Immunoglobulin A (IgA) has two subclasses, IgA1 and IgA2, but differential effects on inflammation are unclear. Here the authors show that IgA2, when compared with IgA1, has stronger pro-inflammatory functions associated with changed glycosylation an
Externí odkaz:
https://doaj.org/article/10d5aea8f2dd4168b05d11de004c1d68
Autor:
Ingrid Zahn, Fabian Garreis, Martin Schicht, Vera Rötzer, Jens Waschke, Yuqiuhe Liu, Valerian L. Altersberger, Friedrich Paulsen, Jana Dietrich
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14947 (2022)
The meibomian glands (MGs) within the eyelids produce a lipid-rich secretion that forms the superficial layer of the tear film. Meibomian gland dysfunction (MGD) results in excessive evaporation of the tear film, which is the leading cause of dry eye
Externí odkaz:
https://doaj.org/article/87400a31584b4132a19d96655cd1c87b
Autor:
Martin Schicht, Kamila Riedlová, Mercedes Kukulka, Wenyue Li, Aurelius Scheer, Fabian Garreis, Christina Jacobi, Friedrich Paulsen, Lukasz Cwiklik, Lars Bräuer
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5783 (2022)
The ocular surface is in constant interaction with the environment and with numerous pathogens. Therefore, complex mechanisms such as a stable tear film and local immune defense mechanisms are required to protect the eye. This study describes the det
Externí odkaz:
https://doaj.org/article/7c26f1cdaa7a48b99c776417555151f6
Autor:
Jessica Feldt, Martin Schicht, Jessica Welss, Kolja Gelse, Stefan Sesselmann, Michael Tsokos, Eileen Socher, Fabian Garreis, Thomas Müller, Friedrich Paulsen
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 723 (2022)
Gelsolin (GSN) is an actin-binding protein involved in cell formation, metabolism and wound closure processes. Since this protein is known to play a role in arthritis, here we investigate how the synovial membrane with its specific synoviocytes contr
Externí odkaz:
https://doaj.org/article/d92a7dffee5a4ba1b2ff2c1c63c6a5ee
The Translational Role of MUC8 in Salivary Glands: A Potential Biomarker for Salivary Stone Disease?
Autor:
Martin Schicht, Adrian Reichle, Mirco Schapher, Fabian Garreis, Benedikt Kleinsasser, Malik Aydin, Afsun Sahin, Heinrich Iro, Friedrich Paulsen
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2330 (2021)
Mucin (MUC) 8 has been shown to play an important role in respiratory disease and inflammatory responses. In the present study, we investigated the question of whether MUC8 is also produced and secreted by salivary glands and whether it may also play
Externí odkaz:
https://doaj.org/article/4b6597e3202640849dc4bfd30c51dc98