Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment

Autor: Mariam R. Farman, Denisa Petráčková, Dilip Kumar, Jakub Držmíšek, Argha Saha, Ivana Čurnová, Jan Čapek, Václava Hejnarová, Fabian Amman, Ivo Hofacker, Branislav Večerek

Publikováno v: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

ABSTRACTBordetella pertussis, the causative agent of whooping cough, is an extracellular, strictly human pathogen. However, it has been shown that B. pertussis cells can escape phagocytic killing and survive in macrophages upon internalization. Our t

Externí odkaz: https://doaj.org/article/821ce2959aed4031b8fc2ce8f67adc55

Comparative Omics Analysis of Historic and Recent Isolates of Bordetella pertussis and Effects of Genome Rearrangements on Evolution

Autor: Ana Dienstbier, Fabian Amman, Denisa Petráčková, Daniel Štipl, Jan Čapek, Jana Zavadilová, Kateřina Fabiánová, Jakub Držmíšek, Dilip Kumar, Mark Wildung, Derek Pouchnik, Branislav Večerek

Publikováno v: Emerging Infectious Diseases, Vol 27, Iss 1, Pp 57-68 (2021)

Despite high vaccination coverage, pertussis is increasing in many industrialized countries, including the Czech Republic. To better understand Bordetella pertussis resurgence, we analyzed historic strains and recent clinical isolates by using a comp

Externí odkaz: https://doaj.org/article/25de9abc0e174758a512f2bdad1e48a1

Gene Expression Profiling of Pseudomonas aeruginosa Upon Exposure to Colistin and Tobramycin

Autor: Anastasia Cianciulli Sesso, Branislav Lilić, Fabian Amman, Michael T. Wolfinger, Elisabeth Sonnleitner, Udo Bläsi

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

Pseudomonas aeruginosa (Pae) is notorious for its high-level resistance toward clinically used antibiotics. In fact, Pae has rendered most antimicrobials ineffective, leaving polymyxins and aminoglycosides as last resort antibiotics. Although several

Externí odkaz: https://doaj.org/article/9cc5c717f70546d3a30976dca41cebd1

MSF: Modulated Sub-graph Finder [version 3; peer review: 1 approved, 2 approved with reservations]

Autor: Mariam R. Farman, Ivo L. Hofacker, Fabian Amman

Publikováno v: F1000Research, Vol 7 (2019)

High throughput techniques such as RNA-seq or microarray analysis have proven to be invaluable for the characterizing of global transcriptional gene activity changes due to external stimuli or diseases. Differential gene expression analysis (DGEA) is

Externí odkaz: https://doaj.org/article/3383cf44114246618170fd11732f1bca

Wastewater monitoring can anchor global disease surveillance systems

Autor: Aparna Keshaviah, Megan B Diamond, Matthew J Wade, Samuel V Scarpino, Warish Ahmed, Fabian Amman, Olusola Aruna, Andrei Badilla-Aguilar, Itay Bar-Or, Andreas Bergthaler, Julie E Bines, Aaron W Bivins, Alexandria B Boehm, Jean-Martin Brault, Jean-Baptiste Burnet, Joanne R Chapman, Angela Chaudhuri, Ana Maria de Roda Husman, Robert Delatolla, John J Dennehy, Megan Beth Diamond, Celeste Donato, Erwin Duizer, Abiodun Egwuenu, Oran Erster, Despo Fatta-Kassinos, Aldo Gaggero, Deirdre F Gilpin, Brent J Gilpin, Tyson E Graber, Christopher A Green, Amanda Handley, Joanne Hewitt, Rochelle H Holm, Heribert Insam, Marc C Johnson, Rabia Johnson, Davey L Jones, Timothy R Julian, Asha Jyothi, Tamar Kohn, Katrin G Kuhn, Giuseppina La Rosa, Marie Lesenfants, Douglas G Manuel, Patrick M D'Aoust, Rudolf Markt, John W McGrath, Gertjan Medema, Christine L Moe, Indah Kartika Murni, Humood Naser, Colleen C Naughton, Leslie Ogorzaly, Vicka Oktaria, Christoph Ort, Popi Karaolia, Ekta H Patel, Steve Paterson, Mahbubur Rahman, Pablo Rivera-Navarro, Alex Robinson, Monica C Santa-Maria, Heike Schmitt, Theodore Smith, Lauren B Stadler, Jorgen Stassijns, Alberta Stenico, Renee A Street, Elisabetta Suffredini, Zachary Susswein, Monica Trujillo, Marlene K Wolfe, Habib Yakubu, Maria Ines Zanoli Sato

Publikováno v: Keshaviah, A, Diamond, M B, Wade, M J, Scarpino, S V, Ahmed, W, Amman, F, Aruna, O, Badilla-Aguilar, A, Bar-Or, I, Bergthaler, A, Bines, J E, Bivins, A W, Boehm, A B, Brault, J-M, Burnet, J-B, Chapman, J R, Chaudhuri, A, de Roda Husman, A M, Delatolla, R, Dennehy, J J, Diamond, M B, Donato, C, Duizer, E, Egwuenu, A, Erster, O, Fatta-Kassinos, D, Gaggero, A, Gilpin, D F, Gilpin, B J, Graber, T E, Green, C A, Handley, A, Holm, R H, Insam, H, Johnson, M C, Johnson, R, Jones, D L, Julian, T R, Jyothi, A, Kohn, T, Kuhn, K G, La Rosa, G, Lesenfants, M, Manuel, D G, D'Aoust, P M, Markt, R, McGrath, J W, Medema, G, Moe, C L, Murni, I K, Naser, H, Naughton, C C, Ogorzaly, L, Oktaria, V, Ort, C, Karaolia, P, Patel, E H, Paterson, S, Rahman, M, Rivera-Navarro, P, Robinson, A, Santa-Maria, M C, Schmitt, H, Smith, T, Stadler, L B, Stassijns, J, Stenico, A, Street, R A, Suffredini, E, Susswein, Z, Trujillo, M, Wolfe, M K, Yakubu, H & Zanoli Sato, M I 2023, ' Wastewater monitoring can anchor global disease surveillance systems ', The Lancet Global Health, vol. 11, no. 6, pp. e976-e981 . https://doi.org/10.1016/S2214-109X(23)00170-5

To inform the development of global wastewater monitoring systems, we surveyed programmes in 43 countries. Most programmes monitored predominantly urban populations. In high-income countries (HICs), composite sampling at centralised treatment plants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cdcb7cd24a1ffe3de14b12692127c7
https://pure.qub.ac.uk/en/publications/25208d6c-5bd8-4b09-ad27-2286b2974293