Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fabia Mittendorf"'
Autor:
Michael Tapera, Federica Borghi, Jan Lukas Mayer-Figge, Fabia Mittendorf, Ibrahim-Ethem Celik, Adrián Gómez-Suárez, Stefan F. Kirsch
Publikováno v:
Molecules, Vol 29, Iss 15, p 3710 (2024)
Herein, we report a concise and efficient formal synthesis of (+)-hannokinol. Key to this new strategy is the use of a chiral Horner–Wittig reagent, readily available from 2-deoxy-D-ribose, to introduce the chiral 1,3-diol motif.
Externí odkaz:
https://doaj.org/article/bb1dccd0ed3240f6aef22f9723bc06af
Publikováno v:
Tetrahedron Chem, Vol 9, Iss , Pp 100065- (2024)
The macrolide bastimolide A represents an attractive synthetic target due to its promising activity against resistant strains of the malaria pathogen plasmodium falciparum. We report a straightforward formal synthesis of bastimolide A using a Horner-
Externí odkaz:
https://doaj.org/article/cbf8505d37a843c5a4821e817fef56a6
Publikováno v:
The Journal of Organic Chemistry. 87:14899-14908
The modular synthesis of 1,3-polyols using a chiral phosphine oxide building block is reported. This versatile building block works in a repetitive way for the stereocontrolled synthesis of a tetraol key intermediate, which serves for the first total
Publikováno v:
Organic & Biomolecular Chemistry.
The first de novo synthesis of (−)- and (+)-aureosurfactin, using a chiral Horner–Wittig building block. Both enantiomers of the biosurfactant are easily accessible starting from only one chiral pool via a bidirectional synthetic strategy.
Publikováno v:
The Journal of Organic Chemistry. 85:12760-12769
A novel ring expansion based on the readily available 2-azido-2-phenyl-indan-1,3-dione is described. Treatment with primary amines and cesium carbonate in a two-step sequence gives rise to 3-amino-2,3-dihydroisoquinoline-1,4-diones with an unpreceden
Publikováno v:
European Journal of Organic Chemistry. 2020:4389-4398