Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fabián Lopez-Vallejo"'
Autor:
Juliet A. Prieto-Rodríguez, Kevin P. Lévuok-Mena, Juan C. Cardozo-Muñoz, Jorge E. Parra-Amin, Fabián Lopez-Vallejo, Luis E. Cuca-Suárez, Oscar J. Patiño-Ladino
Publikováno v:
Plants, Vol 11, Iss 17, p 2188 (2022)
Digestive enzymes are currently considered important therapeutic targets for the treatment of obesity and some associated metabolic diseases, such as type 2 diabetes. Piper cumanense is a species characterized by the presence of bioactive constituent
Externí odkaz:
https://doaj.org/article/4236b611486747f4ace501710b3ca748
Autor:
Juan Cardozo-Muñoz, Luis E. Cuca-Suárez, Juliet A. Prieto-Rodríguez, Fabian Lopez-Vallejo, Oscar J. Patiño-Ladino
Publikováno v:
Molecules, Vol 27, Iss 10, p 3283 (2022)
Digestive enzymes such α-amylase (AA), α-glucosidase (AG) and pancreatic lipase (PL), play an important role in the metabolism of carbohydrates and lipids, being attractive therapeutic targets for the treatment of type 2 diabetes and obesity. Garci
Externí odkaz:
https://doaj.org/article/b2dbe663f33944bf87befde87f45c2fa
Autor:
Diego Muñoz, Martina Brucoli, Silvia Zecchini, Adrian Sandoval-Hernandez, Gonzalo Arboleda, Fabian Lopez-Vallejo, Wilman Delgado, Matteo Giovarelli, Marco Coazzoli, Elisabetta Catalani, Clara De Palma, Cristiana Perrotta, Luis Cuca, Emilio Clementi, Davide Cervia
Publikováno v:
Cancers, Vol 11, Iss 9, p 1336 (2019)
X-linked inhibitor of apoptosis protein (XIAP) is an emerging crucial therapeutic target in cancer. We report on the discovery and characterisation of small organic molecules from Piper genus plants exhibiting XIAP antagonism, namely erioquinol, a qu
Externí odkaz:
https://doaj.org/article/36161f3ec13d4f00949c0c61c717ed23
Autor:
Robert Kraft, Allon Kahn, José L. Medina-Franco, Mikayla L. Orlowski, Cayla Baynes, Fabian López-Vallejo, Kobus Barnard, Gerald M. Maggiora, Linda L. Restifo
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 217-235 (2013)
SUMMARY The actin-bundling protein fascin is a key mediator of tumor invasion and metastasis and its activity drives filopodia formation, cell-shape changes and cell migration. Small-molecule inhibitors of fascin block tumor metastasis in animal mode
Externí odkaz:
https://doaj.org/article/6dcc206b5f884de0935effbcba21cb6f