Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fabián Frommel"'
Publikováno v:
2023 IEEE Wireless Communications and Networking Conference (WCNC).
Phosphorylation‐linked complex profiling identifies assemblies required for Hippo signal integration
Autor:
Federico Uliana, Rodolfo Ciuffa, Ranjan Mishra, Andrea Fossati, Fabian Frommelt, Sabrina Keller, Martin Mehnert, Eivind Salmorin Birkeland, Frank van Drogen, Nevena Srejic, Matthias Peter, Nicolas Tapon, Ruedi Aebersold, Matthias Gstaiger
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 4, Pp 1-25 (2023)
Abstract While several computational methods have been developed to predict the functional relevance of phosphorylation sites, experimental analysis of the interdependency between protein phosphorylation and Protein–Protein Interactions (PPIs) rema
Externí odkaz:
https://doaj.org/article/87d8299e1ad24511acc6e8b026e4e491
Autor:
Federico Uliana, Matej Vizovišek, Laura Acquasaliente, Rodolfo Ciuffa, Andrea Fossati, Fabian Frommelt, Sandra Goetze, Bernd Wollscheid, Matthias Gstaiger, Vincenzo De Filippis, Ulrich auf dem Keller, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Characterizing proteases in their native environment is still challenging. Here, the authors develop a proteomics workflow for analyzing protease-specific peptides from cell lysates in 96-well format, providing mechanistic insights into blood proteas
Externí odkaz:
https://doaj.org/article/db933c0d43874f78b25c2f9000538975
Autor:
Martin Mehnert, Rodolfo Ciuffa, Fabian Frommelt, Federico Uliana, Audrey van Drogen, Kilian Ruminski, Matthias Gstaiger, Ruedi Aebersold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Diseases can be associated with various mutations of the same gene, but the molecular consequences of specific mutations remain incompletely understood. Here, the authors present an integrated proteomic workflow to determine the molecular response of
Externí odkaz:
https://doaj.org/article/5284796b9f7e4306aca01803fd9b2199
Autor:
Joana G Marques, Berkley E Gryder, Blaz Pavlovic, Yeonjoo Chung, Quy A Ngo, Fabian Frommelt, Matthias Gstaiger, Young Song, Katharina Benischke, Dominik Laubscher, Marco Wachtel, Javed Khan, Beat W Schäfer
Publikováno v:
eLife, Vol 9 (2020)
The NuRD complex subunit CHD4 is essential for fusion-positive rhabdomyosarcoma (FP-RMS) survival, but the mechanisms underlying this dependency are not understood. Here, a NuRD-specific CRISPR screen demonstrates that FP-RMS is particularly sensitiv
Externí odkaz:
https://doaj.org/article/d33cd1744564400abf93c1226f3c6a09