Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fabián Flores-Borja"'
Autor:
Rodolfo Soria-Castro, Yatsiri G. Meneses-Preza, Gloria M. Rodríguez-López, Alfredo Ibarra-Sánchez, Claudia González-Espinosa, Sonia M. Pérez-Tapia, Fabián Flores-Borja, Sergio Estrada-Parra, Alma D. Chávez-Blanco, Rommel Chacón-Salinas
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Mast cells (MC) play a central role in the early containment of bacterial infections, such as that caused by Listeria monocytogenes (L.m). The mechanisms of MC activation induced by L.m infection are well known, so it is possible to evaluate
Externí odkaz:
https://doaj.org/article/4947b02a7fa84d529c56f5f8f7d64ef0
Autor:
Rosalind Graham, Patrycja Gazinska, Birong Zhang, Atousa Khiabany, Shubhankar Sinha, Thanussuyah Alaguthurai, Fabian Flores-Borja, Jose Vicencio, Fabienne Beuron, Ioannis Roxanis, Rafal Matkowski, Revadee Liam-Or, Andrew Tutt, Tony Ng, Khuloud T. Al-Jamal, You Zhou, Sheeba Irshad
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIntracellular communication within the tumour is complex and extracellular vesicles (EVs) have been identified as major contributing factors for the cell-to-cell communication in the local and distant tumour environments. Here, we examine t
Externí odkaz:
https://doaj.org/article/6751835215264410a344fd60c77e7254
Autor:
Paul R Barber, Rami Mustapha, Fabian Flores-Borja, Giovanna Alfano, Kenrick Ng, Gregory Weitsman, Luigi Dolcetti, Ali Abdulnabi Suwaidan, Felix Wong, Jose M Vicencio, Myria Galazi, James W Opzoomer, James N Arnold, Selvam Thavaraj, Shahram Kordasti, Jana Doyle, Jon Greenberg, Magnus T Dillon, Kevin J Harrington, Martin Forster, Anthony CC Coolen, Tony Ng
Publikováno v:
eLife, Vol 11 (2022)
Background: Advanced head and neck squamous cell carcinoma (HNSCC) is associated with a poor prognosis, and biomarkers that predict response to treatment are highly desirable. The primary aim was to predict progression-free survival (PFS) with a mult
Externí odkaz:
https://doaj.org/article/f01407f956a24b9e8f9a0385ed5d4e28
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Innate lymphoid cells (ILCs) are largely tissue resident and respond rapidly toward the environmental signals from surrounding tissues and other immune cells. The pleiotropic function of ILCs in diverse contexts underpins its importance in the innate
Externí odkaz:
https://doaj.org/article/300f34bd2e2742dbb386595610e7f18d
Autor:
James Monypenny, Hanna Milewicz, Fabian Flores-Borja, Gregory Weitsman, Anthony Cheung, Ruhe Chowdhury, Thomas Burgoyne, Appitha Arulappu, Katherine Lawler, Paul R. Barber, Jose M. Vicencio, Melanie Keppler, Wahyu Wulaningsih, Sean M. Davidson, Franca Fraternali, Natalie Woodman, Mark Turmaine, Cheryl Gillett, Dafne Franz, Sergio A. Quezada, Clare E. Futter, Alex Von Kriegsheim, Walter Kolch, Borivoj Vojnovic, Jeremy G. Carlton, Tony Ng
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 630-641 (2018)
Summary: The immunosuppressive transmembrane protein PD-L1 was shown to traffic via the multivesicular body (MVB) and to be released on exosomes. A high-content siRNA screen identified the endosomal sorting complexes required for transport (ESCRT)-as
Externí odkaz:
https://doaj.org/article/271d76a1d4d644ff8f8a80c533ecdc3e
Autor:
Rachel Evans, Fabian Flores-Borja, Sina Nassiri, Elena Miranda, Katherine Lawler, Anita Grigoriadis, James Monypenny, Cheryl Gillet, Julie Owen, Peter Gordon, Victoria Male, Anthony Cheung, Farzana Noor, Paul Barber, Rebecca Marlow, Erika Francesch-Domenech, Gilbert Fruhwirth, Mario Squadrito, Borivoj Vojnovic, Andrew Tutt, Frederic Festy, Michele De Palma, Tony Ng
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 1967-1978.e4 (2019)
Summary: Lymphatic vasculature is crucial for metastasis in triple-negative breast cancer (TNBC); however, cellular and molecular drivers controlling lymphovascular metastasis are poorly understood. We define a macrophage-dependent signaling cascade
Externí odkaz:
https://doaj.org/article/4742772908ef465eb5e9bd0d61b0e92a
Autor:
Fabian Flores-Borja, Sheeba Irshad, Peter Gordon, Felix Wong, Ibrahim Sheriff, Andrew Tutt, Tony Ng
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
Our knowledge and understanding of the tumor microenvironment (TME) have been recently expanded with the recognition of the important role of innate lymphoid cells (ILC). Three different groups of ILC have been described based on their ability to pro
Externí odkaz:
https://doaj.org/article/1de2fd39c6f248f990b2629dd3c53a46