When the cold gets under your skin: Evidence for brown adipose tissue activity in Samoan adults.

Autor: Niclou A; Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.; Department of Anthropology, University of Notre Dame, Notre Dame, Indiana, USA., Vesi L; Obesity, Lifestyle and Genetic Adaptations (OLaGA) Study Group, Apia, Samoa., Arorae M; Obesity, Lifestyle and Genetic Adaptations (OLaGA) Study Group, Apia, Samoa., Naseri NC; Obesity, Lifestyle and Genetic Adaptations (OLaGA) Study Group, Apia, Samoa., Faasalele Savusa K; Obesity, Lifestyle and Genetic Adaptations (OLaGA) Study Group, Apia, Samoa., Naseri T; Samoa Ministry of Health, Apia, Samoa., DeLany JP; AdventHealth Orlando, Translational Research Institute, Orlando, Florida, USA., McGarvey ST; International Health Institute & Departments of Epidemiology and Anthropology, Brown University, Providence, Rhode Island, USA., Rivara AC; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA., Ocobock C; Department of Anthropology, University of Notre Dame, Notre Dame, Indiana, USA.; Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, USA.

Publikováno v: American journal of biological anthropology [Am J Biol Anthropol] 2024 Feb; Vol. 183 (2), pp. e24848. Date of Electronic Publication: 2023 Sep 23.

The association of CREBRF variant rs373863828 with body composition in adult Samoans

Autor: Vesi L, Nicola L. Hawley, Emily M. Russell, Abigail I. Wetzel, Jenna C. Carlson, Lupematisila, Erin E. Kershaw, Selu M, Unasa F, Stephen T. McGarvey, Ranjan Deka, Faasalele-Savusa K, Take Naseri, Alysa Pomer, Anna C Rivara, Daniel E. Weeks, Muagututi’a S. Reupena, Lameko, Rachel L. Duckham, Ryan L. Minster, Unasa S, Fatu T, Satupaitea Viali

ObjectiveThe minor allele of rs373863828, a missense variant in CREBRF, is associated with higher BMI but lower odds of type 2 diabetes in Pacific Islanders.MethodsTo test if this protective effect operates through metabolically favorable body fat di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::394cc9adb8abd341df551d386afc309e
https://doi.org/10.1101/2021.02.11.21251582

The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans.

Autor: Hawley NL; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, Connecticut, USA., Duckham RL; Institute of Physical Activity and Nutrition, Deakin University, Melbourne, Victoria, Australia.; Australian Institute for Musculoskeletal Science (AIMSS), The University of Melbourne, Western Health, St Albans, Victoria, Australia., Carlson JC; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Naseri T; Ministry of Health, Apia, Samoa., Reupena MS; Lutia I Puava Ae Mapu I Fagalele, Apia, Samoa., Lameko V; Oceania University of Medicine, Apia, Samoa., Pomer A; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, Connecticut, USA., Wetzel A; International Health Institute, Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, USA., Selu M; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Lupematisila V; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Unasa F; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Vesi L; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Fatu T; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Unasa S; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Faasalele-Savusa K; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Rivara AC; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, Connecticut, USA., Russell E; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Delany JP; AdventHealth, Translational Research Institute, Orlando, Florida, USA., Viali S; School of Medicine, National University of Samoa, Apia, Samoa., Kershaw EE; Division of Endocrinology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Minster RL; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Weeks DE; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., McGarvey ST; International Health Institute, Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, USA.

Publikováno v: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2022 Dec; Vol. 30 (12), pp. 2468-2476. Date of Electronic Publication: 2022 Oct 25.

Exploring the Paradoxical Relationship of a Creb 3 Regulatory Factor Missense Variant With Body Mass Index and Diabetes Among Samoans: Protocol for the Soifua Manuia (Good Health) Observational Cohort Study.

Autor: Hawley NL; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States., Pomer A; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States., Rivara AC; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States., Rosenthal SL; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States., Duckham RL; Institute of Physical Activity and Nutrition, Deakin University, Geelong, Australia.; Australian Institute for Musculoskeletal Sciences, The University of Melbourne and Western Health, St Albans, Australia., Carlson JC; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States., Naseri T; Ministry of Health, Apia, Samoa., Reupena MS; Lutia I Puava Ae Mapu I Fagalele, Apia, Samoa., Selu M; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Lupematisila V; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Unasa F; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Vesi L; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Fatu T; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Unasa S; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Faasalele-Savusa K; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Wetzel AI; International Health Institute, Department of Epidemiology, School of Public Health, Brown University, Providence, RI, United States., Soti-Ulberg C; Ministry of Health, Apia, Samoa., Prescott AT; Department of Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States., Siufaga G; Obesity, Lifestyle and Genetic Adaptations Study Group, Apia, Samoa., Penaia C; Asian Pacific Islander Forward Movement, Los Angeles, CA, United States., To SB; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, United States., LaMonica LC; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, United States., Lameko V; Oceania University of Medicine, Apia, Samoa., Choy CC; International Health Institute, Department of Epidemiology, School of Public Health, Brown University, Providence, RI, United States., Crouter SE; Department of Kinesiology, Recreation, and Sport Studies, The University of Tennessee Knoxville, Knoxville, TN, United States., Redline S; Departments of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States., Deka R; Department of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, OH, United States., Kershaw EE; Division of Endocrinology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States., Urban Z; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States., Minster RL; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States., Weeks DE; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States., McGarvey ST; International Health Institute, Department of Epidemiology, School of Public Health, Brown University, Providence, RI, United States.; Department of Anthropology, Brown University, Providence, RI, United States.

Publikováno v: JMIR research protocols [JMIR Res Protoc] 2020 Jul 23; Vol. 9 (7), pp. e17329. Date of Electronic Publication: 2020 Jul 23.

Pearl Memorial Lecture. Humans at the extremes: Exploring human adaptation to ecological and social stressors.

Autor: Leonard WR; Department of Anthropology & Program in Global Health Studies, Northwestern University, Evanston, Illinois, USA.

Publikováno v: American journal of human biology : the official journal of the Human Biology Council [Am J Hum Biol] 2024 Mar; Vol. 36 (3), pp. e24010. Date of Electronic Publication: 2023 Nov 16.