Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Fa-zhong He"'
Autor:
Ling Li, Bao-jia Zou, Juan-zhi Zhao, Jia-bi Liang, Zi-yue She, Wen-ying Zhou, Si-xiao Lin, Lin Tian, Wen-ji Luo, Fa-zhong He
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
DNA damage repair (DDR) is essential for maintaining genome integrity and modulating cancer risk, progression, and therapeutic response. DDR defects are common among non-small lung cancer (NSCLC), resulting in new challenge and promise for NSCLC trea
Externí odkaz:
https://doaj.org/article/cff4c70b515646369735719d90026ce1
Autor:
Rui-Qi Wang, Xiao-Ran Long, Ning-Ning Zhou, Dong-Ni Chen, Mei-Yin Zhang, Zhe-Sheng Wen, Lan-Jun Zhang, Fa-Zhong He, Zhi-Lin Zhou, Shi-Juan Mai, Hui-Yun Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Long non-coding RNAs (lncRNAs) play vital roles in the development and progression of non-small-cell lung cancer (NSCLC); however, the role of most lncRNAs in NSCLC remains unknown. This study explored the clinical significance, b
Externí odkaz:
https://doaj.org/article/7df4d752f9324a568549e9c8a07d8d2b
Autor:
Rui-Qi Wang, Wei Zhao, Hai-Kui Yang, Jia-Mei Dong, Wei-Jie Lin, Fa-Zhong He, Min Cui, Zhi-Ling Zhou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Colorectal cancer (CRC) manifests as gastrointestinal tumors with high intratumoral heterogeneity. Recent studies have demonstrated that CRC may consist of tumor cells with different consensus molecular subtypes (CMS). The advancements in single-cell
Externí odkaz:
https://doaj.org/article/c3fee79df1a54903a73211536d0a71db
Autor:
Wang-Qing Chen, Yan Shu, Qing Li, Lin-Yong Xu, Mary W Roederer, Lan Fan, Lan-Xiang Wu, Fa-Zhong He, Jian-Quan Luo, Zhi-Rong Tan, Yi-Jing He, Hong-Hao Zhou, Xiang Chen, Wei Zhang
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70341 (2013)
BACKGROUND:The pharmacokinetics (PKs) and pharmacodynamics (PDs) of telmisartan varies among the individuals, and the main causes remain unknown. The aim of this study was to evaluate the impact of ORM1, as well as ABCC2, ABCB1, ABCG2 and SLCO1B3 pol
Externí odkaz:
https://doaj.org/article/4c647e2a453147efbefd72d4520830d7
Autor:
Rui-Qi, Wang, Fa-Zhong, He, Qian, Meng, Wei-Jie, Lin, Jia-Mei, Dong, Hai-Kui, Yang, Yang, Yang, Min, Zhao, Wen-Tao, Qiu, Yong-Jie, Xin, Zhi-Ling, Zhou
Publikováno v:
Ann Transl Med
BACKGROUND: Tribble pseudokinase 3 (TRIB3) plays a key role in regulating the malignancy of many tumors. This study examined its function in cancer cells and explored the potential mechanisms of action. METHODS: The expression of TRIB3 was examined i
Autor:
Zhe-Sheng Wen, Lan-Jun Zhang, Rui-Qi Wang, Shi-Juan Mai, Hui-Yun Wang, Fa-Zhong He, Dongni Chen, Xiaoran Long, Zhi-Lin Zhou, Mei-Yin Zhang, Ningning Zhou
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Long non-coding RNAs (lncRNAs) play vital roles in the development and progression of non-small-cell lung cancer (NSCLC); however, the role of most lncRNAs in NSCLC remains unknown. This study explored the clinical significance, biological
Autor:
Wang, Rui-Qi, Xiao-Ran Long, Zhou, Ning-Ning, Dong-Ni Chen, Zhang, Mei-Yin, Zhe-Sheng Wen, Zhang, Lan-Jun, Fa-Zhong He, Zhou, Zhi-Lin, Mai, Shi-Juan, Wang, Hui-Yun
Additional file 1: Supplementary Table S1. Sequences of primers and siRNA used in this study. Supplementary Table S2. Univariate and multivariate Cox regression analyses of factors associated with overall survival in patients with NSCLC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbcebc09b86cffbb871876f8a023034
Publikováno v:
Endocrine. 63:489-496
Diabetes mellitus is a major chronic disease and causes over one million deaths. KCNJ11 genetic polymorphisms influence the response of first-line oral antidiabetic agent sulfonylureas. Hsa-miR-4532 correlates with diabetic nephropathy and has a high
Autor:
Yuan-Feng Gao, Yi-Xin Chen, Zhao-Qian Liu, Wei Zhang, Xiang Chen, Dong-Bo Zhou, Tao Zhu, Ling Li, Hong-Hao Zhou, Lun-Quan Sun, Ji-Ye Yin, Ma-Sha Huang, Fa-Zhong He
Publikováno v:
Oncotarget
// Ling Li 1, 2 , Ji-Ye Yin 1, 2 , Fa-Zhong He 1, 2 , Ma-Sha Huang 1, 2 , Tao Zhu 1, 2 , Yuan-Feng Gao 1, 2 , Yi-Xin Chen 1, 2 , Dong-Bo Zhou 3 , Xiang Chen 4 , Lun-Quan Sun 5 , Wei Zhang 1, 2 , Hong-Hao Zhou 1, 2 and Zhao-Qian Liu 1, 2 1 Department
Autor:
Zhao-Qian Liu, Hua-Wen Xin, Wei Zhang, Yong-Fang Hu, Hai-Yan He, Fa-Zhong He, Xiao-Ping Chen, Hong-Hao Zhou, Ying-zi Ming, Zhiying Luo, Ming-Jie Shao, Mou-Ze Liu, Jian-Quan Luo, Yue-Li Zhang
Publikováno v:
Acta Pharmacologica Sinica. 38:415-423
The highly variable pharmacokinetics and narrow therapeutic window of tacrolimus (TAC) has hampered its clinical use. Genetic polymorphisms may contribute to the variable response, but the evidence is not compelling, and the explanation is unclear. I