Výsledky vyhledávání - "Fábio L. Forti"

Akademický článek

Intracellular Peptides in Cell Biology and Pharmacology

Autor: Christiane B. de Araujo, Andrea S. Heimann, Ricardo A. Remer, Lilian C. Russo, Alison Colquhoun, Fábio L. Forti, Emer S. Ferro

Publikováno v: Biomolecules, Vol 9, Iss 4, p 150 (2019)

Intracellular peptides are produced by proteasomes following degradation of nuclear, cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases generating a larger pool of peptides within cells. Thousands of intracel

Externí odkaz: https://doaj.org/article/d3ce3ad7d3864fa293cfb66a60311681

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Supplementary Table 1 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Autor: Hugo A. Armelin, Marianna M. Koga, Celina K. Yoshihara, Paula F. Asprino, Kátia M. Rocha, Jacqueline Salotti, Fábio Nakano, Alexandre Dermargos, Tatiana G.F. Matos, Fábio L. Forti, Érico T. Costa

Supplementary Table 1 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4ba71128b7d5124591139e92b6084f
https://doi.org/10.1158/0008-5472.22374059

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Supplementary Figures 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Supplementary Figures 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514848a91f63cd0e2e0d45bdb51175ac
https://doi.org/10.1158/0008-5472.22374062

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Data from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Fibroblast growth factor 2 (FGF2) is considered to be a bona fide oncogenic factor, although results from our group and others call this into question. Here, we report that exogenous recombinant FGF2 irreversibly inhibits proliferation by inducing se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df18ccea0863a760d7c022c9cf65eed7
https://doi.org/10.1158/0008-5472.c.6497321

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Supplementary Figure Legends 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Supplementary Figure Legends 1-8 from Fibroblast Growth Factor 2 Restrains Ras-Driven Proliferation of Malignant Cells by Triggering RhoA-Mediated Senescence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5953fad9222df4f80db09aff5e10e498
https://doi.org/10.1158/0008-5472.22374065.v1

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Measuring the Contributions of the Rho Pathway to the DNA Damage Response in Tumor Epithelial Cells

Autor: Yuli T, Magalhães, Jessica O, Farias, Lucas F, Monteiro, Fábio L, Forti

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1821

Actin polymerization, actomyosin ring contraction, and stress fiber formation are examples of relevant actions of the RhoA/B/C pathway as GTPases that regulate the cytoskeleton. However, open questions that remain to be addressed are whether this pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6ffabf1640515f6dece7f2783d05b22
https://pubmed.ncbi.nlm.nih.gov/30062423

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Assessing the Roles of Rho GTPases in Cell DNA Repair by the Nucleotide Excision Repair Pathway

Autor: Lilian C, Russo, Pault Y, Minaya, Luiz E, Silva, Fábio L, Forti

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1821

Ultraviolet light crossing the ozone layer in the atmospheric barrier affects all forms of living beings on earth. In eukaryotic cells, the nucleotide excision repair (NER) pathway protects the DNA by removing cyclobutane pyrimidine dimers (CPDs) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f8195d2acd9b798fe44dd32b07dd6c9
https://pubmed.ncbi.nlm.nih.gov/30062422

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Akademický článek

Nucleophosmin Protein Dephosphorylation by DUSP3 Is a Fine-Tuning Regulator of p53 Signaling to Maintain Genomic Stability

Autor: Lilian C. Russo, Pault Y. M. Ferruzo, Fabio L. Forti

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

The dual-specificity phosphatase 3 (DUSP3), an atypical protein tyrosine phosphatase (PTP), regulates cell cycle checkpoints and DNA repair pathways under conditions of genotoxic stress. DUSP3 interacts with the nucleophosmin protein (NPM) in the cel

Externí odkaz: https://doaj.org/article/2fd5d7a1f80c4b94b7f0d5d3fbe0f434

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Akademický článek

RHOAming Through the Nucleotide Excision Repair Pathway as a Mechanism of Cellular Response Against the Effects of UV Radiation

Autor: Yuli T. Magalhaes, Gisele E. T. Silva, Juliana H. Osaki, Clarissa R. R. Rocha, Fabio L. Forti

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Typical Rho GTPases include the enzymes RhoA, Rac1, and Cdc42 that act as molecular switches to regulate essential cellular processes in eukaryotic cells such as actomyosin dynamics, cell cycle, adhesion, death and differentiation. Recently, it has b

Externí odkaz: https://doaj.org/article/67f9a01880a44b65834d1794a71e4aaa

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