Induction, mobilization of peripheral blood stem cells (PBSC), high-dose chemotherapy and PBSC infusion in patients with untreated stage IV breast cancer: outcomes by intent to treat analyses

Autor: Raefsky E, Kalman L, R Leff, WH West, FA Greco, B McAneny, Buckner Cd, C H Weaver, M Magee, J Hainsworth, T. Alberico, Lee S. Schwartzberg, R Birch

Publikováno v: Bone Marrow Transplantation. 19:661-670

Summary: complete remission (CR) rates (40‐50%) with median overall survivals of 18‐24 months and progression-free survivals (PFS) of 12‐25% in patients with breast cancer We investigated the outcomes of patients with breast cancer undergoing i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0913572075e88adf15a955e52c4398b
https://doi.org/10.1038/sj.bmt.1700728

Treatment-related mortality in 1000 consecutive patients receiving high-dose chemotherapy and peripheral blood progenitor cell transplantation in community cancer centers

Autor: Li W, C H Weaver, WH West, FA Greco, J Hainsworth, Lee S. Schwartzberg, Buckner Cd

Publikováno v: Bone marrow transplantation. 19(7)

Summary: cancer centers. 10‐14 This report describes the 100-day treatment-related mortality (TRM) of the first 1000 consecutive patients receiving high-dose myeloablative chemotherapy High-dose chemotherapy (HDC) with autologous peripheral blood p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9f12aa6ca6f6e3258d4792884daf27
https://pubmed.ncbi.nlm.nih.gov/9156243

Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting.

Autor: Greco FA; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Krämer A; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), DKTK Site Frankfurt-Mainz, 69120 Heidelberg, Germany., Wahl L; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Elson L; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Ehret TAL; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Gerninghaus J; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Möckel J; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Müller S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany., Hanke T; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany. Electronic address: hanke@pharmchem.uni-frankfurt.de., Knapp S; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt Am Main, Germany; Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt Am Main, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), DKTK Site Frankfurt-Mainz, 69120 Heidelberg, Germany. Electronic address: knapp@pharmchem.uni-frankfurt.de.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Oct 05; Vol. 276, pp. 116672. Date of Electronic Publication: 2024 Jul 14.

Molecular guided therapies: a practice-changing step forward in cancer of unknown primary management.

Autor: Rassy E; Gustave Roussy, Départements de Médecine Oncologique, 94805 Villejuif, France; Université Paris-Saclay, Gustave Roussy, Institut national de la santé et de la recherche médicale U1018, Villejuif, France. Electronic address: elie.el-rassy@gustaveroussy.fr., Greco FA; Sarah Cannon Cancer Center, Tennessee Oncology, Nashville, TN, USA., Pavlidis N; University of Ioannina, Ioannina, Greece.

Publikováno v: Lancet (London, England) [Lancet] 2024 Aug 10; Vol. 404 (10452), pp. 496-497. Date of Electronic Publication: 2024 Jul 31.

International consensus on the initial diagnostic workup of cancer of unknown primary.

Autor: van der Strate I; Department of Research and Development, Comprehensive Cancer Organization the Netherlands, Utrecht, the Netherlands. Electronic address: i.h.vander.strate@student.vu.nl., Kazemzadeh F; Department of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands., Nagtegaal ID; Department of Pathology, Radboud University Medical Centre, Nijmegen, the Netherlands., Robbrecht D; Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands., van de Wouw A; Department of Medical Oncology, VieCuri Medical Center, Venlo, the Netherlands., Padilla CS; Department of Research and Development, Comprehensive Cancer Organization the Netherlands, Utrecht, the Netherlands., Duijts S; Department of Research and Development, Comprehensive Cancer Organization the Netherlands, Utrecht, the Netherlands; Department of Medical Psychology, Cancer Center Amsterdam, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Esteller M; Josep Carreras Leukemia Research Institute (IJC), Badalona, Barcelona, Catalonia, Spain; Centro de Investigacion Biomedica en Red Cancer (CIBERONC), Madrid, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain; Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), Barcelona, Catalonia, Spain., Greco FA; Sarah Cannon Research Institute and Cancer Center, Tennessee Oncology, Nashville, TN, USA., Pavlidis N; Medical School, University of Ioannina, Stavros Niarchou Avenue, 45110, Ioannina, Greece., Qaseem A; American College of Physicians, Philadelphia, PA, USA., Snaebjornsson P; Department of Pathology, The Netherlands Cancer Institute, 1066 CX, Amsterdam, the Netherlands., van Zanten SV; Department of Radiology and Nuclear Medicine, Erasmus MC, Dr. Molewaterplein 40, 3015 GD, Rotterdam, the Netherlands., Loef C; Department of Research and Development, Comprehensive Cancer Organization the Netherlands, Utrecht, the Netherlands.

Publikováno v: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2023 Jan; Vol. 181, pp. 103868. Date of Electronic Publication: 2022 Nov 23.