PEOPLE WITH MILD HEMOPHILIA ARE AT RISK OF JOINT DISEASE: THE NATIONWIDE COHORT HIN-6 STUDY

Autor: RM Camelo, C Smit, J Eikenboom, F Rosendaal, LFD van Vulpen, EAM Beckers, L Hooimeijer, M Coppens, SEM Schols, FWG Leebeek, MH Driessens, JGVD Bom, SM Rezende, SC Gouw

Publikováno v: Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S561-S562 (2024)

Clinical data on people with mild hemophilia (mPwH) is important to guide their treatment but remains scarce worldwide. In addition, since modern hemophilia therapies can turn severe phenotypes into mild or normal ones, knowing the clinical, therapeu

Externí odkaz: https://doaj.org/article/f01b98d651fe4bb3a898374288d1abcc

Is pharmacokinetic-guided dosing of desmopressin and von Willebrand factor-containing concentrates in individuals with von Willebrand disease or low von Willebrand factor reliable and feasible? A protocol for a multicentre, non-randomised, open label cohort trial, the OPTI-CLOT: to WiN study

Autor: Marjon H Cnossen, Frank W G Leebeek, Ron A A Mathôt, M Coppens, MJHA Kruip, S Polinder, K Fischer, R Liesner, K Fijnvandraat, Laura H Bukkems, PW Collins, P Chowdary, K Meijer, A Janssen, MH Cnossen, Jessica M Heijdra, Wala Al Arashi, Nico C B de Jager, Michael E Cloesmeijer, Christian M Zwaan, FWG Leebeek, RAA Mathôt, RYJ Tamminga, BAP Laros-van Gorkom, P Brons, SEM Schols, FJM van der Meer, HCJ Eikenboom, REG Schutgens, F Heubel-Moenen, L Nieuwenhuizen, P Ypma, MHE Driessens, CM Zwaan, I van Vliet, D Keeling, J Lock, HCAM Hazendonk, I van Moort, T Preijers, JM Heijdra, NCB de Jager, MCHJ Goedhart, LH Bukkems, W Al Arashi, ME Cloesmeijer

Publikováno v: BMJ Open, Vol 12, Iss 2 (2022)

Externí odkaz: https://doaj.org/article/1965d1889ddf4cbeb8a1d66664e6a252

Successful treatment with daratumumab for splenectomy refractory immune-mediated thrombotic thrombocytopenic purpura.

Autor: Jansen AJG; Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Rab MAE; Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Te Boekhorst PAW; Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Leebeek FWG; Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

Publikováno v: British journal of haematology [Br J Haematol] 2024 Oct 20. Date of Electronic Publication: 2024 Oct 20.

Prediction of the chance of successful immune tolerance induction in persons with severe hemophilia A and inhibitors: a clinical prediction model.

Autor: Oomen I; Department of Pediatric Hematology, Amsterdam University Medical Centers location University of Amsterdam, Amsterdam, the Netherlands.; Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Abdi A; Department of Pediatric Hematology, Amsterdam University Medical Centers location University of Amsterdam, Amsterdam, the Netherlands., Camelo RM; Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Callado FMRA; Fundação de Hematologia e Hemoterapia de Pernambuco, Recife, Brazil., Carvalho LEM; Centro de Hematologia e Hemoterapia do Ceará, Fortaleza, Brazil., Calcaterra IL; Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy., Carcao M; Department of Pediatrics, Division of Hematology and Oncology, Hospital for Sick Children, Toronto, Ontario, Canada., Castaman G; Department of Oncology, Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Florence, Italy., Eikenboom JCJ; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands., Fischer K; Department of Hematology, Center for Benign Hematology, Thrombosis and Hemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, the Netherlands., Franco VKB; Centro de Hematologia e Hemoterapia de Santa Catarina, Florianópolis, Brazil., Heymans MW; Department of Epidemiology and Biostatistics, Amsterdam University Medical Centers, Vrije Universiteit University, Amsterdam, the Netherlands.; Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands., Leebeek FWG; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Lillicrap D; Department of Pathology and Molecular Medicine, Queen's University, Kingston, Ontario, Canada., Lorenzato CS; Coagulopathy Clinic, Hemocentro do Paraná, Curitiba, Brazil., Mancuso ME; Department of Hematology, Center for Thrombosis and Hemorrhagic Diseases, Instituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital, Rozzano, Milan, Italy., Matino D; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Di Minno MND; Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy., Mohseny AB; Department of Pediatrics, Leiden University Medical Center, Leiden, the Netherlands., Oldenburg J; Institute of Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Medical Faculty, University of Bonn, Bonn, Germany., Rezende SM; Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Rivard GE; Molecular Diagnostic Laboratory, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada.; Department of Pediatrics, Division of Hematology-Oncology, Montréal University, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Québec, Canada., Rydz N; Department of Hematology and Hematologic Malignancies, Foothills Medical Center, Calgary, Alberta, Canada., Schols SEM; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.; Hemophilia Treatment Center Nijmegen-Eindhoven-Maastricht, Nijmegen, the Netherlands., Voorberg J; Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Fijnvandraat K; Department of Pediatric Hematology, Amsterdam University Medical Centers location University of Amsterdam, Amsterdam, the Netherlands.; Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Gouw SC; Department of Pediatric Hematology, Amsterdam University Medical Centers location University of Amsterdam, Amsterdam, the Netherlands.

Publikováno v: Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2024 Oct 03; Vol. 8 (7), pp. 102580. Date of Electronic Publication: 2024 Oct 03 (Print Publication: 2024).

Variant mapping using mass spectrometry-based proteotyping as a diagnostic tool in von Willebrand disease.

Autor: Kreft IC; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands. Electronic address: i.kreft@sanquin.nl., van Duijl TT; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., van Kwawegen C; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Atiq F; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Phan W; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Schuller MBP; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Boon-Spijker M; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., van der Zwaan C; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Meijer AB; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands., Hoogendijk AJ; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands., Bierings R; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., Eikenboom JCJ; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands., Leebeek FWG; Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands., van den Biggelaar M; Laboratory of Proteomics, Department of Molecular Hematology, Sanquin Research, Amsterdam, the Netherlands. Electronic address: m.vandenbiggelaar@sanquin.nl.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Jul; Vol. 22 (7), pp. 1894-1908. Date of Electronic Publication: 2024 Apr 27.