Zobrazeno 1 - 10
of 74
pro vyhledávání: '"FUMIHITO ONO"'
Autor:
Kazuki Nishimura, Kiyoshi Takahara, Kazumasa Komura, Mitsuaki Ishida, Kensuke Hirosuna, Ryoichi Maenosono, Masahiko Ajiro, Moritoshi Sakamoto, Kengo Iwatsuki, Yuki Nakajima, Takuya Tsujino, Kohei Taniguchi, Tomohito Tanaka, Teruo Inamoto, Yoshinobu Hirose, Fumihito Ono, Yoichi Kondo, Akihide Yoshimi, Haruhito Azuma
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Hyper progressive disease (HPD) is a paradoxical phenomenon characterized by accelerated tumor growth following treatment with immune checkpoint inhibitors. However, the pathogenic causality and its predictor remain unknown. We herein report
Externí odkaz:
https://doaj.org/article/8552f31aaae046989d490218ab175216
Autor:
Shiori Naruoka, Souhei Sakata, Shigeru Kawabata, Yasuyuki Hashiguchi, Eriko Daikoku, Shoichi Sakaguchi, Fumiyoshi Okazaki, Kento Yoshikawa, John F. Rawls, Takashi Nakano, Yoshinobu Hirose, Fumihito Ono
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37510- (2024)
In the process of investigating synaptic changes happening to mutants lacking postsynaptic receptors in the neuromuscular junction, we focused on a hitherto uncharacterized zebrafish gene zgc153932 whose expression was increased in the RNAseq and dro
Externí odkaz:
https://doaj.org/article/48649a7e2c4b41a4852a793a3ccdd31e
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-8 (2024)
Abstract The models used to investigate the pathophysiological mechanisms of acute critical illness are not limited to mammalian species. The zebrafish (Danio rerio) is a popular model organism for studying diseases due to its transparency and rapid
Externí odkaz:
https://doaj.org/article/c620c7aaf70e42f9ad9e8e9982c826a3
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Exposure of testes to high-temperature environment results in defective spermatogenesis. Zebrafish exposed to high temperature exhibited apoptosis not only in germ cells but also in Leydig cells, as expected from studies using mice or salmon
Externí odkaz:
https://doaj.org/article/f6db46e67eca47c192c54771b7d8ee4e
Autor:
Kazumasa Komura, Kensuke Hirosuna, Satoshi Tokushige, Takuya Tsujino, Kazuki Nishimura, Mitsuaki Ishida, Takuo Hayashi, Ayako Ura, Takaya Ohno, Shogo Yamazaki, Keita Nakamori, Shoko Kinoshita, Ryoichi Maenosono, Masahiko Ajiro, Yuki Yoshikawa, Tomoaki Takai, Takeshi Tsutsumi, Kohei Taniguchi, Tomohito Tanaka, Kiyoshi Takahara, Tsuyoshi Konuma, Teruo Inamoto, Yoshinobu Hirose, Fumihito Ono, Yuichi Shiraishi, Akihide Yoshimi, Haruhito Azuma
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Currently, only limited knowledge is available regarding the phenotypic association between fibroblast growth factor receptor 3 (FGFR3) alterations and the tumor microenvironment (TME) in bladder cancer (BLCA). Methods A multi-omi
Externí odkaz:
https://doaj.org/article/44ae7691b7154435adafb64297a43998
Autor:
Souhei Sakata, Fumihito Ono
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292262 (2023)
Muscle relaxants are indispensable for surgical anesthesia. Early studies suggested that a classical non-depolarizing muscle relaxant pancuronium competitively binds to the ligand binding site to block nicotinic acetylcholine receptors (nAChR). Our g
Externí odkaz:
https://doaj.org/article/65af77c3d1254bb8a47bd0510ee5f9e4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The mating behavior of teleost fish consists of a sequence of stereotyped actions. By observing mating of zebrafish under high-speed video, we analyzed and characterized a behavioral cascade leading to successful fertilization. When paired,
Externí odkaz:
https://doaj.org/article/7dfd508390ad4e01a85f4142d730d22c
Autor:
Kana Yamamoto, Toshihiko Kuriu, Kensuke Matsumura, Kazuki Nagayasu, Yoshinori Tsurusaki, Noriko Miyake, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Mikiya Fujiwara, Masayuki Baba, Kohei Kitagawa, Tomoya Takemoto, Nanaka Gotoda-Nishimura, Tomohiro Takada, Kaoru Seiriki, Atsuko Hayata-Takano, Atsushi Kasai, Yukio Ago, Satoshi Kida, Kazuhiro Takuma, Fumihito Ono, Naomichi Matsumoto, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract An increasing body of evidence suggests that impaired synapse development and function are associated with schizophrenia; however, the underlying molecular pathophysiological mechanism of the disease remains largely unclear. We conducted a f
Externí odkaz:
https://doaj.org/article/8394ac62854447c697f5bccde4c28363
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
A line of studies in the 1960s–1980s suggested that muscle relaxants do not work uniformly on all skeletal muscles, though its mechanism has not been clarified. We showed here that a classical non-depolarizing muscle relaxant pancuronium inhibits f
Externí odkaz:
https://doaj.org/article/ab1fafa2e6c1475fa4331daf7de46342
Autor:
Kensuke Fujii, Koichi Nakajo, Yoshihiro Egashira, Yasuhiro Yamamoto, Kazuya Kitada, Kohei Taniguchi, Masaru Kawai, Hideki Tomiyama, Koichi Kawakami, Kazuhisa Uchiyama, Fumihito Ono
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108314- (2020)
Externí odkaz:
https://doaj.org/article/4b40d67fd59e45efac01c69318129325