Zobrazeno 1 - 3
of 3
pro vyhledávání: '"FTD, frontotemporal degeneration"'
Autor:
Satoko Komatsu-Hirota, Yu-shin Sou, Masaaki Komatsu, Mohammad Omar Faruk, Nobuo N. Noda, Shun Kageyama, Yoshinobu Ichimura, Afnan H. El-Gowily, Masato Koike
Publikováno v:
The Journal of Biological Chemistry
Summary Several amyotrophic lateral sclerosis (ALS)-related proteins such as FUS, TDP-43, and hnRNPA1 demonstrate liquid-liquid phase separation, and their disease-related mutations correlate with a transition of their liquid droplet form into aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9984bac28fcd074c4fc72342ddc213
https://pubmed.ncbi.nlm.nih.gov/34774801
https://pubmed.ncbi.nlm.nih.gov/34774801
Autor:
David J. Irwin, James C. Gee, Vivianna M. Van Deerlin, Christopher Olm, Philip A. Cook, Murray Grossman, Corey T. McMillan
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 19, Iss, Pp 497-506 (2018)
NeuroImage: Clinical, Vol 19, Iss, Pp 497-506 (2018)
Introduction Mutations in the progranulin (GRN) gene are a major source of inherited frontotemporal degeneration (FTD) spectrum disorders associated with TDP-43 proteinopathy. We use structural MRI to identify regions of baseline differences and long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d85a4b488666bff120c93271c00fd7f
https://doi.org/10.1016/j.nicl.2018.05.017
https://doi.org/10.1016/j.nicl.2018.05.017
Autor:
Olm CA; Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States; Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States., McMillan CT; Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States., Irwin DJ; Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States; Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, United States., Van Deerlin VM; Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, United States., Cook PA; Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States., Gee JC; Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States., Grossman M; Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States. Electronic address: mgrossma@pennmedicine.upenn.edu.
Publikováno v:
NeuroImage. Clinical [Neuroimage Clin] 2018 May 15; Vol. 19, pp. 497-506. Date of Electronic Publication: 2018 May 15 (Print Publication: 2018).