Zobrazeno 1 - 10
of 101
pro vyhledávání: '"FRET biosensors"'
Autor:
Peng, Qin, Lu, Shaoying, Shi, Yuxin, Pan, Yijia, Limsakul, Praopim, Chernov, Andrei V., Qiu, Juhui, Chai, Xiaoqi, Shi, Yiwen, Wang, Pengzhi, Ji, Yanmin, Li, Yi-Shuan J., Strongin, Alex Y., Verkhusha, Vladislav V., Belmonte, Juan Carlos Izpisua, Ren, Bing, Wang, Yuanliang, Chien, Shu, Wang, Yingxiao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Dec 01. 115(50), E11681-E11690.
Externí odkaz:
https://www.jstor.org/stable/26580181
Autor:
Alessia Floerchinger, Kendelle J. Murphy, Sharissa L. Latham, Sean C. Warren, Andrew T. McCulloch, Young-Kyung Lee, Janett Stoehr, Pauline Mélénec, Cris S. Guaman, Xanthe L. Metcalf, Victoria Lee, Anaiis Zaratzian, Andrew Da Silva, Michael Tayao, Sonia Rolo, Monica Phimmachanh, Ghazal Sultani, Laura McDonald, Susan M. Mason, Nicola Ferrari, Lisa M. Ooms, Anna-Karin E. Johnsson, Heather J. Spence, Michael F. Olson, Laura M. Machesky, Owen J. Sansom, Jennifer P. Morton, Christina A. Mitchell, Michael S. Samuel, David R. Croucher, Heidi C.E. Welch, Karen Blyth, C. Elizabeth Caldon, David Herrmann, Kurt I. Anderson, Paul Timpson, Max Nobis
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109689- (2021)
Summary: Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Förster resonance energy transfer (
Externí odkaz:
https://doaj.org/article/60a7564e516e42fe894cc587d92fc98e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The accuracy of biosensor ratio imaging is limited by signal/noise. Signals can be weak when biosensor concentrations must be limited to avoid cell perturbation. This can be especially problematic in imaging of low volume regions, e.g., along the cel
Externí odkaz:
https://doaj.org/article/bcba59249c794b4093ca9d8ea64fb226
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Revealing mechanisms underpinning cell function requires understanding the relationship between different biochemical reactions in living cells. However, our capabilities to monitor more than two biochemical reactions in living cells are limited. The
Externí odkaz:
https://doaj.org/article/2faad21430234a5091ee09a7acfd498a
Autor:
Pham, Elizabeth
Optogenetics has emerged as a branch of biotechnology that combines genetic engineering with optics to observe intracellular changes as well as control cellular function. Despite recent progress, there still remains the need for an optogenetic tool t
Externí odkaz:
http://hdl.handle.net/1807/31898
Autor:
Ponsioen, Bas, Post, Jasmin B., Buissant des Amorie, Julian R., Laskaris, Dimitrios, van Ineveld, Ravian L., Kersten, Simone, Bertotti, Andrea, Sassi, Francesco, Sipieter, François, Cappe, Benjamin, Mertens, Sander, VerlaanKlink, Ingrid, Boj, Sylvia F., Vries, Rob G.J., Rehmann, Holger, Vandenabeele, Peter, Riquet, Franck B., Trusolino, Livio, Bos, Johannes L., Snippert, Hugo J.G.
Direct targeting of the downstream mitogen-activated protein kinase (MAPK) pathway to suppress extracellular-regulated kinase (ERK) activation in KRAS and BRAF mutant colorectal cancer (CRC) has proven clinically unsuccessful, but promising results h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::568fb538c15baa7f32c1c1edc2e05ee2
https://zenodo.org/record/7801498
https://zenodo.org/record/7801498
Autor:
Laura M. Machesky, Sharissa L. Latham, Karen Blyth, Owen J. Sansom, Paul Timpson, Cris S. Guaman, Victoria Lee, Nicola Ferrari, Anaiis Zaratzian, Sean C. Warren, Susan M. Mason, Pauline Mélénec, Lisa M Ooms, C. Elizabeth Caldon, Andrew M. Da Silva, Andrew T. McCulloch, Michael F. Olson, Xanthe L. Metcalf, Ghazal Sultani, Monica Phimmachanh, David Herrmann, Michael Tayao, Max Nobis, Alessia Floerchinger, Janett Stoehr, Jennifer P. Morton, Anna-Karin E. Johnsson, Christina Anne Mitchell, Heather J. Spence, Kendelle J. Murphy, David R. Croucher, Sonia Rolo, Heidi C.E. Welch, Young-Kyung Lee, Michael S. Samuel, Laura McDonald, Kurt I. Anderson
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109689-(2021)
Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Forster resonance energy transfer (FRET) bios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e60a0a238c9fea39f12263962e274fc
Autor:
Lebrec, Vicente
Publikováno v:
Biologie cellulaire. Université Paris-Saclay, 2021. Français. ⟨NNT : 2021UPASL011⟩
Replication stress is a major source of genomic instability and oncogene-induced replication stress has been proposed to play a key role in cancer development. Accordingly, the checkpoint mechanisms that prevent cell cycle progression under condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5b327f51c67be91dccdd0897e5c634e1
https://theses.hal.science/tel-03506282
https://theses.hal.science/tel-03506282
Autor:
Livio Trusolino, Francesco Sassi, Sander Mertens, Benjamin Cappe, Ingrid Verlaan-Klink, Ravian L. van Ineveld, Bas Ponsioen, Sylvia F. Boj, Simone Kersten, Julian R. Buissant des Amorie, Dimitrios Laskaris, Rob G. J. Vries, Franck B. Riquet, Andrea Bertotti, Jasmin B. Post, François Sipieter, Johannes L. Bos, Peter Vandenabeele, Hugo J. Snippert, Holger Rehmann
Publikováno v:
Nature cell biology
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, 23 (4), pp.377-390. ⟨10.1038/s41556-021-00654-5⟩
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, 23 (4), pp.377-390. ⟨10.1038/s41556-021-00654-5⟩
Direct targeting of the downstream mitogen-activated protein kinase (MAPK) pathway to suppress extracellular-regulated kinase (ERK) activation in KRAS and BRAF mutant colorectal cancer (CRC) has proven clinically unsuccessful, but promising results h
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.