Zobrazeno 1 - 10
of 206
pro vyhledávání: '"FRET—fluorescence resonance energy transfer"'
Autor:
Gaoxian Chen, Detlef Obal
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
G protein-coupled receptors (GPCRs) are a large family of transmembrane proteins that play a major role in many physiological processes, and thus GPCR-targeted drug development has been widely promoted. Although research findings generated in immorta
Externí odkaz:
https://doaj.org/article/11f1ca797d714431a232757207cb5d13
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
14-3-3 proteins are a family of regulatory hubs that function through a vast network of protein-protein interactions. Their dysfunction or dysregulation is implicated in a wide range of diseases, and thus they are attractive drug targets, especially
Externí odkaz:
https://doaj.org/article/343f1cb228b9417ab2ea51bb41934737
Autor:
Yahui Li, Sapermsap Natakorn, Yu Chen, Mohammed Safar, Margaret Cunningham, Jinshou Tian, David Day-Uei Li
Publikováno v:
Frontiers in Physics, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/5b66bfdfe1154f61aaf1bea3db1382c8
Autor:
Yahui Li, Sapermsap Natakorn, Yu Chen, Mohammed Safar, Margaret Cunningham, Jinshou Tian, David Day-Uei Li
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Intensity- and amplitude-weighted average lifetimes, denoted as τI and τA hereafter, are useful indicators for revealing Förster resonance energy transfer (FRET) or fluorescence quenching behaviors. In this work, we discussed the differences betwe
Externí odkaz:
https://doaj.org/article/1d4d8ec4f636431d8e668ac6ed971d2c
Publikováno v:
Sensors, Vol 21, Iss 23, p 8033 (2021)
Polymer solutions under shear flow are often observed in manufacturing processes. Classically, polymer behavior is represented by Kuhn’s bead-spring model, in which only the elongation of polymer chains is assumed. In recent years, the compression
Externí odkaz:
https://doaj.org/article/42589480848645ecb759c87e1e94f89e
Autor:
Hanjie Wang, Jin Chang, Kun Ge, Jinchao Zhang, Yu Tian, Chaonan Zhang, Wang Tiange, Yingying Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1978-1992 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Tumor recurrence after surgery is the main cause of treatment failure. However, the initial stage of recurrence is not easy to detect, and it is difficult to cure in the late stage. In order to improve the life quality of postoperative patients, an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b427dfc66786d16834b8e45da6c2b16
http://www.sciencedirect.com/science/article/pii/S2211383521001076
http://www.sciencedirect.com/science/article/pii/S2211383521001076
Autor:
Caifang Gao, Peng Liu, Hongguo Chen, Xu Wu, Xudong Tang, Yitao Wang, Chi Teng Vong, Shengpeng Wang
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2798-2818 (2021)
Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical manifestations and high risks of cancerization. With no curative therapy for IBD at present, the development of effective therapeutics is highly advocated. Drug de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf33f667c4f81b143c5ccef5cfb99fc
http://europepmc.org/articles/PMC8463263
http://europepmc.org/articles/PMC8463263
Publikováno v:
Sensors, Vol 21, Iss 8033, p 8033 (2021)
Sensors (Basel, Switzerland)
Sensors (Basel, Switzerland)
Polymer solutions under shear flow are often observed in manufacturing processes. Classically, polymer behavior is represented by Kuhn’s bead-spring model, in which only the elongation of polymer chains is assumed. In recent years, the compression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a3d0bb5cfe89c528242b910f912a62
https://www.mdpi.com/1424-8220/21/23/8033
https://www.mdpi.com/1424-8220/21/23/8033
Publikováno v:
The Journal of Biological Chemistry
Lack of simple and robust methods to determine complement activation in human serum induced by antigen-antibody complexes is a major hurdle for monitoring therapeutic antibody drug quality and stability. Dezamizumab is a humanized IgG1 monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f933513331869a4d84c72fbc9ba7fd
http://europepmc.org/articles/PMC8463879
http://europepmc.org/articles/PMC8463879
Autor:
Sua Myong, Chun-Ying Lee
Publikováno v:
The Journal of Biological Chemistry
Transcriptional regulation is one of the key steps in determining gene expression. Diverse single-molecule techniques have been applied to characterize the stepwise progression of transcription, yielding complementary results. These techniques includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456e2078a8fb6b08158f653b59c859e3
http://europepmc.org/articles/PMC8441165
http://europepmc.org/articles/PMC8441165