Zobrazeno 1 - 10 of 477 pro vyhledávání: '"FREDRIC L. COE"'
1
Akademický článek
A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease
Autor: Victor Hugo Canela, William S. Bowen, Ricardo Melo Ferreira, Farooq Syed, James E. Lingeman, Angela R. Sabo, Daria Barwinska, Seth Winfree, Blue B. Lake, Ying-Hua Cheng, Joseph P. Gaut, Michael Ferkowicz, Kaice A. LaFavers, Kun Zhang, Fredric L. Coe, Elaine Worcester, the Kidney Precision Medicine Project, Sanjay Jain, Michael T. Eadon, James C. Williams, Tarek M. El-Achkar
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Kidney stone disease causes significant morbidity and increases health care utilization. In this work, we decipher the cellular and molecular niche of the human renal papilla in patients with calcium oxalate (CaOx) stone disease and healthy
Externí odkaz: https://doaj.org/article/9079daace87a49889ca16163b6717e46
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2
Akademický článek
A Precision Medicine Approach Uncovers a Unique Signature of Neutrophils in Patients With Brushite Kidney Stones
Autor: Mohammad Shahidul Makki, Seth Winfree, James E. Lingeman, Frank A. Witzmann, Elaine M. Worcester, Amy E. Krambeck, Fredric L. Coe, Andrew P. Evan, Sharon Bledsoe, Kristin J. Bergsland, Suraj Khochare, Daria Barwinska, James C. Williams, Jr., Tarek M. El-Achkar
Publikováno v: Kidney International Reports, Vol 5, Iss 5, Pp 663-677 (2020)
Introduction: We have previously found that papillary histopathology differs greatly between calcium oxalate and brushite stone formers (SF); the latter have much more papillary mineral deposition, tubular cell injury, and tissue fibrosis. Methods: I
Externí odkaz: https://doaj.org/article/389a098a8d9b451c8f2331649ba7370a
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4
Akademický článek
Evidence for abnormal linkage between urine oxalate and citrate excretion in human kidney stone formers
Autor: Megan L. Prochaska, Orson W. Moe, John R. Asplin, Fredric L. Coe, Elaine M. Worcester
Publikováno v: Physiological Reports, Vol 9, Iss 13, Pp n/a-n/a (2021)
Abstract Background Animal models have demonstrated an interactive relationship between the epithelial anion exchanger SLC26A6 and transporter NaDC‐1 that regulates citrate and oxalate homeostasis. This relationship is a potential mechanism to prot
Externí odkaz: https://doaj.org/article/35b5ed30865e4b4888b781a86fe52e4c
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10
Racial Differences in Risk Factors for Kidney Stone Formation
Autor: Andrew J. Cohen, Fredric L. Coe, Elaine M. Worcester, Christopher B. Riedinger, Anna L. Zisman
Publikováno v: Clin J Am Soc Nephrol
BACKGROUND AND OBJECTIVES: Incidence of kidney stone disease is rising. It is not known whether mechanisms of stone formation differ across racial groups. Our objective was to identify differing lithogenic risk factors across racial groups in idiopat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a37022697345597fa9d00e68eb2aede
https://doi.org/10.2215/cjn.12671019
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