Zobrazeno 1 - 10
of 329
pro vyhledávání: '"FRANKLIN H. EPSTEIN"'
Autor:
Isaac E. Stillman, S. Ananth Karumanchi, Mark E. Williams, Franklin H. Epstein, Sarosh Rana, Hui Yi Shan
Publikováno v:
American Journal of Kidney Diseases. 51:1029-1032
Preeclampsia is a serious complication during pregnancy that includes potentially life-threatening risks to the mother and fetus. It may be challenging to distinguish this from other causes of rapidly escalating hypertension, especially in women with
Publikováno v:
Annals of the New York Academy of Sciences. 718:72-82
Autor:
Sharon Maynard, Roberto Romero, S. Ananth Karumanchi, Franklin H. Epstein, Kai F. Yu, Richard J. Levine, Chun Lam, Cong Qian, Baha M. Sibai, Ravi Thadhani, Benjamin P. Sachs
Publikováno v:
New England Journal of Medicine. 355:992-1005
Alterations in circulating soluble fms-like tyrosine kinase 1 (sFlt1), an antiangiogenic protein, and placental growth factor (PlGF), a proangiogenic protein, appear to be involved in the pathogenesis of preeclampsia. Since soluble endoglin, another
Autor:
Franklin H. Epstein, Chun Lam, Cong Qian, Kai Yu, James L. Mills, Richard J. Levine, S. Ananth Karumanchi, Caroline Signore
Publikováno v:
Obstetrics & Gynecology. 108:338-344
Abnormalities in circulating angiogenic factors have been reported in diseases of abnormal placentation, such as preeclampsia and intrauterine growth restriction. Our objective was to determine whether circulating angiogenic factors are altered in an
Autor:
Franklin H. Epstein, Cong Qian, Kai F. Yu, Richard J. Levine, S. Ananth Karumanchi, Sharon Maynard
Publikováno v:
American Journal of Obstetrics and Gynecology. 194:1034-1041
Objective The purpose of this study was to determine whether serum fms-like tyrosine kinase 1 (sFlt1) concentration during preeclampsia were associated with mid trimester blood pressure, other maternal characteristics, or pregnancy outcomes. Study de
Autor:
Vikas P. Sukhatme, Isaac E. Stillman, S. Ananth Karumanchi, Franklin H. Epstein, Sharon Maynard
Publikováno v:
Kidney International. 67(6):2101-2113
Preeclampsia: A renal perspective. Preeclampsia is a syndrome that affects 5% of all pregnancies, producing substantial maternal and perinatal morbidity and mortality. The aim of this review is to summarize our current understanding of the pathogenes
Publikováno v:
Nephron Physiology. 99:p101-p104
Background/Aims: Water diuresis usually increases medullary oxygenation as a result of increased medullary synthesis of prostaglandins, but it is not clear whether this involves activation of cyclooxygenase-1 (COX-1) or cyclooxygenase-2 (COX-2). Meth
Autor:
Chun S. Zuo, Franklin H. Epstein, Marc Cougnon, Olivier Barbier, Philippe Poujeol, Scott Gilbert, Michel Tauc, Grégory Jacquillet
Publikováno v:
Nephron Physiology. 99:p112-115
Publikováno v:
Experimental Biology and Medicine. 230:1-7
For at least 150 years, biological scientists have congregated at marine laboratories, located at the edge of the sea, to explore aquatic life. The purpose of this minireview is to offer a brief perspective on the relevance of this activity to our kn
Autor:
Lucinda England, Sharon Maynard, Vikas P. Sukhatme, Ravi Thadhani, Kai F. Yu, Franklin H. Epstein, Enrique F. Schisterman, Benjamin P. Sachs, Cong Qian, S. Ananth Karumanchi, Richard J. Levine, Kee-Hak Lim, Bahaeddine M Sibai
Publikováno v:
New England Journal of Medicine. 350:672-683
The cause of preeclampsia remains unclear. Limited data suggest that excess circulating soluble fms-like tyrosine kinase 1 (sFlt-1), which binds placental growth factor (PlGF) and vascular endothelial growth factor (VEGF), may have a pathogenic role.