Impaired arterial dilation and increased NOX2 generated oxidative stress in subjects with ataxia-telangiectasia mutated (ATM) kinase

Autor: Lorenzo Loffredo, Annarosa Soresina, Bianca Laura Cinicola, Martina Capponi, Francesca Salvatori, Simona Bartimoccia, Vittorio Picchio, Maurizio Forte, Caterina Caputi, Roberto Poscia, Vincenzo Leuzzi, Alberto Spalice, Pasquale Pignatelli, Raffaele Badolato, Marzia Duse, Francesco Violi, Roberto Carnevale, Anna Maria Zicari, Ilaria Maria Palumbo, Arianna Magna, Alessia Fallarino, Arianna Pannunzio, Enrico Maggio, Chiara Bagnato, Vittoria Cammisotto, Valentina Castellani

Publikováno v: Redox Biology, Vol 77, Iss , Pp 103347- (2024)

Background: Subjects with mutations in the Ataxia-Telangiectasia mutated (ATM) gene encoding for ATM kinase have a greater predisposition to develop atherosclerosis, but the mechanism behind this phenomenon is not yet understood. NADPH oxidase type 2

Externí odkaz: https://doaj.org/article/311ff2b2e19f46d58a4930364cc07b47

Hypoalbuminemia and Risk of Portal Vein Thrombosis in Cirrhosis

Autor: Roberto Cangemi, Valeria Raparelli, Giovanni Talerico, Stefania Basili, Francesco Violi, Palasciano Giuseppe, D’Alitto Felicia, Palmieri Vincenzo Ostilio, Santovito Daniela, Di Michele Dario, Croce Giuseppe, Sacerdoti David, Brocco Silvia, Fasolato Silvano, Cecchetto Lara, Bombonato Giancarlo, Bertoni Michele, Restuccia Tea, Andreozzi Paola, Liguori Maria Livia, Perticone Francesco, Caroleo Benedetto, Perticone Maria, Staltari Orietta, Manfredini Roberto, De Giorgi Alfredo, Averna Maurizio, Giammanco Antonina, Granito Alessandro, Pettinari Irene, Marinelli Sara, Bolondi Luigi, Falsetti Lorenzo, Salvi Aldo, Durante-Mangoni Emanuele, Cesaro Flavio, Farinaro Vincenza, Ragone Enrico, Morana Ignazio, Andriulli Angelo, Ippolito Antonio, Iacobellis Angelo, Niro Grazia, Merla Antonio, Raimondo Giovanni, Maimone Sergio, Cacciola Irene, Varvara Doriana, Drenaggi Davide, Staffolani Silvia, Picardi Antonio, Vespasiani-Gentilucci Umberto, Galati Giovanni, Gallo Paolo, Davì Giovanni, Schiavone Cosima, Santilli Francesca, Tana Claudio, Licata Anna, Soresi Maurizio, Bianchi Giovanni Battista, Carderi Isabella, Pinto Antonio, Tuttolomondo Antonino, Ferrari Giovanni, Gresele Paolo, Fierro Tiziana, Morelli Olivia, Laffi Giacomo, Romanelli Roberto Giulio, Arena Umberto, Stasi Cristina, Gasbarrini Antonio, Gargovich Matteo, Zocco Maria Assunta, Riccardi Laura, Ainora Maria Elena, Capeci William, Martino Giuseppe Pio, Nobili Lorenzo, Cavallo Maurizio, Frugiuele Pierluigi, Greco Antonio, Pietrangelo Antonello, Ventura Paolo, Cuoghi Chiara, Marcacci Matteo, Serviddio Gaetano, Vendemiale Gianluigi, Villani Rosanna, Gargano Ruggiero, Vidili Gianpaolo, Di Cesare Valentina, Masala Maristella, Delitala Giuseppe, Invernizzi Pietro, Di Minno Giovanni, Tufano Antonella, Purrello Francesco, Privitera Graziella, Forgione Alessandra, Curigliano Valentina, Senzolo Marco, Rodríguez-Castro Kryssia Isabel, Giannelli Gianluigi, Serra Carla, Neri Sergio, Pignataro Pietro, Rizzetto Mario, Debernardi Venon Wilma, Svegliati Baroni Gianluca, Bergamaschi Gaetano, Masotti Michela, Costanzo Filippo, Corazza Gino Roberto, Caldwell Stephen Hugh, Angelico Francesco, Del Ben Maria, Napoleone Laura, Polimeni Licia, Proietti Marco, Raparelli Valeria, Romiti Giulio Francesco, Ruscio Eleonora, Severoni Andrea, Talerico Giovanni, Toriello Filippo, Vestri Annarita

Publikováno v: Gastro Hep Advances, Vol 3, Iss 5, Pp 646-653 (2024)

Background and Aims: Hypoalbuminemia, as defined by serum albumin (SA) levels ≤35 g/L, is associated to venous and arterial thrombosis in general population and in patients at risk of cardiovascular disease. It is unknown if SA ≤35 g/L is also as

Externí odkaz: https://doaj.org/article/178a1a7c8e1047f2ac0da978dac4c2b4

Asymptomatic and symptomatic deep venous thrombosis in hospitalized acutely ill medical patients: risk factors and therapeutic implications

Autor: Lorenzo Loffredo, Gianpaolo Vidili, Angela Sciacqua, Chiara Cogliati, Rosella Di Giulio, Sciaila Bernardini, Paolo Ciacci, Antonello Pietrangelo, Federica Orlando, Aurora Paraninfi, Maria Boddi, Giovanni Di Minno, Lorenzo Falsetti, Corrado Lodigiani, Angelo Santoliquido, Evaristo Ettorre, Pasquale Pignatelli, Maria Felice Arezzo, Evghenii Gutu, Job Harenberg, Francesco Violi, AURELIO Study Group

Publikováno v: Thrombosis Journal, Vol 20, Iss 1, Pp 1-9 (2022)

Abstract Background Acutely ill medical patients experience deep venous thrombosis (DVT) during the hospitalization, however the time course of DVT is still unclear. Objectives To evaluate risk factors in acutely ill hospitalized medical patients for

Externí odkaz: https://doaj.org/article/354f1689694c4acc969ac973efc6cc9c

Thrombosis in Covid-19 and non-Covid-19 pneumonia: role of platelets

Autor: Francesco Violi, Vittoria Cammisotto, Pasquale Pignatelli

Publikováno v: Platelets, Vol 32, Iss 8, Pp 1009-1017 (2021)

Platelets may be a target of bacteria and viruses, which can directly or indirectly activate them so promoting thrombosis. In accordance with this, community-acquired pneumonia (CAP) is complicated by ischemia-related vascular disease (myocardial inf

Externí odkaz: https://doaj.org/article/b7aa1ee17b5d4691b9b8870213db0659

Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Advanced Liver Disease: An Exploratory Meta‐Analysis

Autor: Francesco Violi, Annarita Vestri, Danilo Menichelli, Arianna Di Rocco, Daniele Pastori, Pasquale Pignatelli

Publikováno v: Hepatology Communications, Vol 4, Iss 7, Pp 1034-1040 (2020)

Direct oral anticoagulants (DOACs) have had a positive impact in preventing cardioembolic stroke in patients with atrial fibrillation (AF) who were associated with lower bleeding complications; however, data on subjects with concomitant advanced live

Externí odkaz: https://doaj.org/article/940e2219174a426f87703762db54086c