Zobrazeno 1 - 10
of 163
pro vyhledávání: '"FRANCESCA MICCI"'
Autor:
Marta Brunetti, Kristin Andersen, Gunhild Trøen, Francesca Micci, Signe Spetalen, Andrea Lenartova, Maren Randi Tandsæther, Ioannis Panagopoulos
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Background/AimIsodicentric [idic(X)(q13)] and isochromosome [i(X)(q10)] are infrequent aberrations in neoplastic diseases. The former is mainly reported in elderly women with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), whereas th
Externí odkaz:
https://doaj.org/article/654442723fcb4fe689edeb6938f11209
Autor:
Marta Brunetti, Kristin Andersen, Signe Spetalen, Andrea Lenartova, Liv Toril Nygård Osnes, Helen Vålerhaugen, Sverre Heim, Francesca Micci
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAlterations of the NUP214 gene (9q34) are recurrent in acute leukemias. Rearrangements of chromosomal band 9q34 targeting this locus can be karyotypically distinct, for example t(6;9)(p22;q34)/DEK::NUP214, or cryptic, in which case no vis
Externí odkaz:
https://doaj.org/article/6e54dab0855646e29369ccaf4222b21f
Autor:
Hilde K. Gjelberg, Lars Helgeland, Knut Liseth, Francesca Micci, Miriam Sandnes, Hege G. Russnes, Håkon Reikvam
Publikováno v:
Current Oncology, Vol 30, Iss 11, Pp 10007-10018 (2023)
T-prolymphocytic leukemia (T-PLL) is a rare malignancy of mature T-cells with distinct clinical, cytomorphological, and molecular genetic features. The disease typically presents at an advanced stage, with marked leukocytosis, B symptoms, hepatosplen
Externí odkaz:
https://doaj.org/article/6248a833b81a4966a9b67e5e2a9ad5e7
Autor:
William John Hatchett, Marta Brunetti, Kristin Andersen, Maren Randi Tandsæther, Ingvild Lobmaier, Marius Lund-Iversen, Thomas Lien-Dahl, Francesca Micci, Ioannis Panagopoulos
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Introduction: Intramuscular myxomas are benign tumors that are challenging to diagnose, especially on core needle biopsies. Acquired chromosomal aberrations and pathogenic variants in codon 201 or codon 227 in GNAS complex locus gene (GNAS) have been
Externí odkaz:
https://doaj.org/article/caa51687b3b540ae8c432880cf1a8f96
Autor:
Erlend Skaga, Evgeny Kulesskiy, Swapnil Potdar, Ioannis Panagopoulos, Francesca Micci, Iver A. Langmoen, Cecilie J. Sandberg, Einar O. Vik-Mo
Publikováno v:
Translational Oncology, Vol 26, Iss , Pp 101535- (2022)
Serum-free culturing of patient-derived glioblastoma biopsies enrich for glioblastoma stem cells (GSCs) and is recognized as a disease-relevant model system in glioblastoma (GBM). We hypothesized that the temozolomide (TMZ) drug sensitivity of patien
Externí odkaz:
https://doaj.org/article/776418a59d1d4543800713de62d7258d
Autor:
Ioannis Panagopoulos, Marta Brunetti, Margrethe Stoltenberg, Rønnaug A. U. Strandabø, Julie Staurseth, Kristin Andersen, Ilyá Kostolomov, Tarjei S. Hveem, Susanne Lorenz, Tove Anita Nystad, Trond Flægstad, Francesca Micci, Sverre Heim
Publikováno v:
Experimental Hematology & Oncology, Vol 8, Iss 1, Pp 1-8 (2019)
Abstract Background Many cases of acute lymphoblastic leukemia (ALL) carry visible acquired chromosomal changes of pathogenetic, diagnostic, and prognostic importance. Nevertheless, from one-fourth to half of newly diagnosed ALL patients have no visi
Externí odkaz:
https://doaj.org/article/13b4b065f7d140f5873cb80ec0e7758d
Autor:
Ioannis Panagopoulos, Ludmila Gorunova, Hege Kilen Andersen, Astrid Bergrem, Anders Dahm, Kristin Andersen, Francesca Micci, Sverre Heim
Publikováno v:
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-7 (2018)
Abstract Background Acquired primary chromosomal changes in cancer are sometimes found as sole karyotypic abnormalities. They are specifically associated with particular types of neoplasia, essential in establishing the neoplasm, and they often lead
Externí odkaz:
https://doaj.org/article/8d5d0c31fd764089b4c8ed35d9bbe187
Autor:
Marianne Lislerud Smebye, Antonio Agostini, Bjarne Johannessen, Jim Thorsen, Ben Davidson, Claes Göran Tropé, Sverre Heim, Rolf Inge Skotheim, Francesca Micci
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in high-grade serous ovarian carcinomas and have been reported as a common
Externí odkaz:
https://doaj.org/article/87dbcd2ce34d4b30af8c842afc00eb0a
Autor:
Ioannis Panagopoulos, Ludmila Gorunova, Eva-Marie Jacobsen, Kristin Andersen, Francesca Micci, Sverre Heim
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196181 (2018)
Leukemic cells often carry chromosome aberrations which generate chimeric genes of pathogenetic, diagnostic, and prognostic importance. New rearrangements giving rise to novel fusion genes define hitherto unrecognized genetic leukemia subgroups. G-ba
Externí odkaz:
https://doaj.org/article/b19cc9729f3643218e176b4e62f1c8f3
Autor:
Francesca Micci, Ioannis Panagopoulos, Jim Thorsen, Ben Davidson, Claes Gøran Tropé, Sverre Heim
Publikováno v:
PLoS Biology, Vol 12, Iss 2, p e1001784 (2014)
The identification of recurrent gene fusions in common epithelial cancers--for example, TMPRSS2/ERG in prostate cancer and EML4/ALK in nonsmall cell lung carcinomas--has raised the question of whether fusion genes are pathogenetically important also
Externí odkaz:
https://doaj.org/article/144b19da75574a02ae7357c51d9e08ce