Zobrazeno 1 - 10
of 85
pro vyhledávání: '"FRANCESCA GIANNO"'
Autor:
Lucia Pedace, Simone Pizzi, Luana Abballe, Maria Vinci, Celeste Antonacci, Sara Patrizi, Claudia Nardini, Francesca Del Bufalo, Sabrina Rossi, Giulia Pericoli, Francesca Gianno, Zein Mersini Besharat, Luca Tiberi, Angela Mastronuzzi, Elisabetta Ferretti, Marco Tartaglia, Franco Locatelli, Andrea Ciolfi, Evelina Miele
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract In vitro models of pediatric brain tumors (pBT) are instrumental for better understanding the mechanisms contributing to oncogenesis and testing new therapies; thus, ideally, they should recapitulate the original tumor. We applied DNA methyl
Externí odkaz:
https://doaj.org/article/3e271e6514f4435baadb82be0810cbf5
Autor:
Antonio d'Amati, Lavinia Bargiacchi, Sabrina Rossi, Andrea Carai, Luca Bertero, Valeria Barresi, Maria Elena Errico, Anna Maria Buccoliero, Sofia Asioli, Gianluca Marucci, Giada Del Baldo, Angela Mastronuzzi, Evelina Miele, Federica D'Antonio, Elisabetta Schiavello, Veronica Biassoni, Maura Massimino, Marco Gessi, Manila Antonelli, Francesca Gianno
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/4a39333298054212874363fd116dc06c
Autor:
Antonio d’Amati, Lavinia Bargiacchi, Sabrina Rossi, Andrea Carai, Luca Bertero, Valeria Barresi, Maria Elena Errico, Anna Maria Buccoliero, Sofia Asioli, Gianluca Marucci, Giada Del Baldo, Angela Mastronuzzi, Evelina Miele, Federica D’Antonio, Elisabetta Schiavello, Veronica Biassoni, Maura Massimino, Marco Gessi, Manila Antonelli, Francesca Gianno
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, established new approaches to both CNS tumor nomenclature and grading, emphasizing the importance of integrated diagnoses and layered report
Externí odkaz:
https://doaj.org/article/d304074ec20344c6b7696081fd8ca6fc
Autor:
Antonio d’Amati, Francesca Gianno, Luciana Scuccimarri, Michele Lastilla, Raffaella Messina, Francesco Signorelli, Domenico Sergio Zimatore, Sabina Barresi, Evelina Miele, Rita Alaggio, Sabrina Rossi, Eugenio Maiorano, Giuseppe Ingravallo, Felice Giangaspero, Manila Antonelli
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Mesenchymal tumors of the central nervous system (CNS) include numerous entities, with different pathological features and biological behavior. Mesenchymal non-meningothelial tumors are rare and comprise neoplasms that are exclusive to the C
Externí odkaz:
https://doaj.org/article/eac91cf4e2de4977b459376211db7475
Autor:
Maddalena Sbaffone, Marie-Lise Jaffrain-Rea, Lucia Cappabianca, Francesca Carbonara, Francesca Gianno, Tiziana Feola, Marianna Ruggieri, Veronica Zelli, Rita Maccarone, Stefano Guadagni, Marco Clementi, Antonietta Arcella, Vincenzo Esposito, Giulia Carozza, Ilaria Martelli, Antonietta Rosella Farina, Andrew Reay Mackay
Publikováno v:
Biology, Vol 13, Iss 3, p 171 (2024)
Pituitary neuroendocrine tumors (PitNETs) are generally benign but comprise an aggressive, invasive, therapy-resistant, metastatic subset, underpinning a need for novel therapeutic targets. PitNETs exhibit low mutation rates but are associated with c
Externí odkaz:
https://doaj.org/article/16394a057224452daab107042774ee82
Autor:
Giuseppina Catanzaro, Zein Mersini Besharat, Andrea Carai, Natalie Jäger, Elena Splendiani, Carole Colin, Agnese Po, Martina Chiacchiarini, Anna Citarella, Francesca Gianno, Antonella Cacchione, Evelina Miele, Francesca Diomedi Camassei, Marco Gessi, Luca Massimi, Franco Locatelli, David T. W. Jones, Dominique Figarella-Branger, Stefan M. Pfister, Angela Mastronuzzi, Felice Giangaspero, Elisabetta Ferretti
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Pediatric low-grade gliomas (pLGGs), particularly incompletely resected supratentorial tumours, can undergo progression after surgery. However to date, there are no predictive biomarkers for progression. Here, we aimed to identify
Externí odkaz:
https://doaj.org/article/69244695ff9e49f0b2da857c1dfb8362
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 65, Iss 5, Pp 73-82 (2022)
Embryonal tumors are a heterogenous group of neoplasms mostly defined by recurrent genetic driver events. They have been, previously, broadly classified as either medulloblastoma or supratentorial primitive neuroectodermal tumors (PNETs). However, th
Externí odkaz:
https://doaj.org/article/5ce4be7c4ab4470d8145d9325f031508
Autor:
Elena Tirrò, Michele Massimino, Giuseppe Broggi, Chiara Romano, Simone Minasi, Francesca Gianno, Manila Antonelli, Gianmarco Motta, Francesco Certo, Roberto Altieri, Livia Manzella, Rosario Caltabiano, Giuseppe Maria Vincenzo Barbagallo, Francesca Romana Buttarelli, Gaetano Magro, Felice Giangaspero, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The management of patients with Central Nervous System (CNS) malignancies relies on the appropriate classification of these tumors. Recently, the World Health Organization (WHO) has published new criteria underlining the importance of an accurate mol
Externí odkaz:
https://doaj.org/article/8b4a7086a7bf44bdb5b01f6967f63c5b
Autor:
Claudio Ballabio, Marica Anderle, Matteo Gianesello, Chiara Lago, Evelina Miele, Marina Cardano, Giuseppe Aiello, Silvano Piazza, Davide Caron, Francesca Gianno, Andrea Ciolfi, Lucia Pedace, Angela Mastronuzzi, Marco Tartaglia, Franco Locatelli, Elisabetta Ferretti, Felice Giangaspero, Luca Tiberi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Medulloblastoma (MB) is the most common malignant brain tumor in children and among the subtypes, Group 3 MB has the worst outcome. Here, we perform an in vivo, patient-specific screen leading to the identification of Otx2 and c-MYC as stron
Externí odkaz:
https://doaj.org/article/9519a8f838f84cd89a2a82dbc13a35e4
Autor:
Simone Minasi, Francesca Gianno, Hiba Alzoubi, Manila Antonelli, Felice Giangaspero, Francesca Romana Buttarelli
Publikováno v:
Glioma, Vol 3, Iss 3, Pp 105-118 (2020)
Recent advances in genetic and molecular characterization of telomere maintenance mechanisms (TMMs) highlighted their strong relationship with cancer pathogenesis; neoplastic cells rely on two mechanisms to maintain telomere length and escape from re
Externí odkaz:
https://doaj.org/article/5ee1e275a95d4ad2b36e84f5c2695f47