Zobrazeno 1 - 10
of 22
pro vyhledávání: '"FPP, farnesyl pyrophosphate"'
Publikováno v:
Plants, Vol 10, Iss 10, p 2179 (2021)
Terpenoids represent one of the high-value groups of specialized metabolites with vast structural diversity. They exhibit versatile human benefits and have been successfully exploited in several sectors of day-to-day life applications, including cosm
Externí odkaz:
https://doaj.org/article/d27a44369501488a8dbe0d53493a77b9
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1813-1834 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Ginsenosides are a series of glycosylated triterpenoids which belong to protopanaxadiol (PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)- and oleanane (OA)-type saponins known as active compounds of Panax genus. They are accumulated in plant roots, s
Publikováno v:
Plants, Vol 10, Iss 2179, p 2179 (2021)
Plants
Plants
Terpenoids represent one of the high-value groups of specialized metabolites with vast structural diversity. They exhibit versatile human benefits and have been successfully exploited in several sectors of day-to-day life applications, including cosm
Publikováno v:
Biotechnology Reports, Vol 28, Iss, Pp e00563-(2020)
Biotechnology Reports
Biotechnology Reports
Highlights • APB are phylogenetically and metabolically diverse, includes many extremophiles. • Ability to harvest IR light and use of many inorganic electron donors useful. • Electricity, polymers, fertilizers, feed, antioxidants and pigments
Autor:
Gilles Truan, Thomas Lautier, Andreas Tholey, Hery Rabeharindranto, Luis F. Garcia-Alles, Sara Castaño-Cerezo, Christian Treitz
Publikováno v:
Metabolic Engineering Communications
Metabolic Engineering Communications, 2019, 8, pp.e00086. ⟨10.1016/j.mec.2019.e00086⟩
Metabolic Engineering Communications, Vol 8, Iss, Pp-(2019)
Metabolic Engineering Communications, 2019, 8, pp.e00086. ⟨10.1016/j.mec.2019.e00086⟩
Metabolic Engineering Communications, Vol 8, Iss, Pp-(2019)
Spatial clustering of enzymes has proven an elegant approach to optimize metabolite transfer between enzymes in synthetic metabolic pathways. Among the multiple methods used to promote colocalisation, enzyme fusion is probably the simplest. Inspired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4f2e3148db37a8277785861d58d037
https://hal.archives-ouvertes.fr/hal-02325530
https://hal.archives-ouvertes.fr/hal-02325530
Publikováno v:
The Journal of Biological Chemistry
Polyprenyl groups, products of isoprenoid metabolism, are utilized in peptidoglycan biosynthesis, protein N-glycosylation, and other processes. These groups are formed by cis-prenyltransferases, which use allylic prenyl pyrophosphates as prenyl-donor
Publikováno v:
Bioscience Reports, Vol 32, Iss 6 (2012)
Bioscience Reports
Bioscience Reports
Osteoporosis is a common disease in the elderly population. The progress of this disease results in the reduction of bone mass and can increase the incidence of fractures. Drugs presently used clinically can block the aggravation of this disease. How
Autor:
Masanori Ikeda, Nobuyuki Kato
Publikováno v:
Advanced Drug Delivery Reviews
The therapy for chronic hepatitis C (CH-C) started with interferon (IFN) monotherapy in the early 1990s and this therapy was considered effective in about 10% of cases. The present standard therapy of pegylated IFN with ribavirin achieves a sustained
Autor:
Maria K, Tsoumpra, Joao R, Muniz, Bobby L, Barnett, Aaron A, Kwaasi, Ewa S, Pilka, Kathryn L, Kavanagh, Artem, Evdokimov, Richard L, Walter, Frank, Von Delft, Frank H, Ebetino, Udo, Oppermann, R Graham G, Russell, James E, Dunford
Publikováno v:
Bone
Farnesyl pyrophosphate synthase (FPPS) is the major molecular target of nitrogen-containing bisphosphonates (N-BPs), used clinically as bone resorption inhibitors. We investigated the role of threonine 201 (Thr201) and tyrosine 204 (Tyr204) residues
Autor:
Peggy Benad-Mehner, Andy Göbel, Maria Junker, Lorenz C. Hofbauer, Peyman Hadji, Tilman D. Rachner, Josefa Hötzel
Publikováno v:
Journal of Bone Oncology
Aminobisphosphonates are used for the treatment of benign and malignant bone disorders. As inhibitors of the mevalonate pathway they exert direct anti-tumor effects in vitro and in preclinical models of bone metastases. Bisphosphonates are thought to