Zobrazeno 1 - 10
of 31 625
pro vyhledávání: '"FOXP3"'
Autor:
Becker A, Röhrich K, Leske A, Heinicke U, Knape T, Kannt A, Trümper V, Sohn K, Wilken-Schmitz A, Neb H, Adam EH, Laux V, Parnham MJ, Onasch V, Weigert A, Zacharowski K, von Knethen A
Publikováno v:
ImmunoTargets and Therapy, Vol Volume 13, Pp 595-616 (2024)
Antonia Becker,1 Karoline Röhrich,1 Amanda Leske,1 Ulrike Heinicke,1 Tilo Knape,2 Aimo Kannt,2,3 Verena Trümper,4 Kai Sohn,5 Annett Wilken-Schmitz,1 Holger Neb,1 Elisabeth H Adam,1 Volker Laux,2 Michael J Parnham,2 Valerie Onasch,4 Andreas Weigert,
Externí odkaz:
https://doaj.org/article/deb4c474a3804763b80e9aa908eb6669
Publikováno v:
Exploration of Immunology, Vol 4, Iss 5, Pp 640-657 (2024)
The impaired function of regulatory T (Treg) cells and the imbalance of Treg/Th17 cells play a central role in developing autoimmune diseases such as systemic lupus erythematosus (SLE). Treg cells are crucial for maintaining immune homeostasis and to
Externí odkaz:
https://doaj.org/article/59550e72828c4c598e075e79010c057c
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 16, Pp 705-723 (2024)
Chunlei Tan,1 Jinling Xu,2 Shiyuan Zhang,1 Shuqiang Liu,1 Xiaotian Yang,1 Danping Wu,1 Boqian Yu,1 Yuanxi Huang1 1Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, 150081, People’s Republic of China; 2En
Externí odkaz:
https://doaj.org/article/3f97c95570ab47faba480a288558d2db
Autor:
Asami Suto, Takeo Minaguchi, Nan Qi, Kaoru Fujieda, Hiroya Itagaki, Yuri Tenjimbayashi, Ayumi Shikama, Nobutaka Tasaka, Azusa Akiyama, Sari Nakao, Chigusa Nakahashi-Oda, Yusuke Kobayashi, Akira Shibuya, Toyomi Satoh
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Regulatory T (Treg) cells reportedly play crucial roles in tumor angiogenesis as well as antitumor immunity. In order to explore their therapeutic potential, we investigated the precise prognostic impact of Treg markers in endomet
Externí odkaz:
https://doaj.org/article/6f42ba3886614c63a495397bd9f88619
Autor:
Maria Isabel Carvalho, Ricardo Silva-Carvalho, Justina Prada, Carla Pinto, Hugo Gregório, Luis Lobo, Isabel Pires, Felisbina L. Queiroga
Publikováno v:
Veterinary Quarterly, Vol 44, Iss 1, Pp 1-12 (2024)
Transforming growth factor-β (TGFβ) and FoxP3 regulatory T cells (Treg) are involved in human breast carcinogenesis. This topic is not well documented in canine mammary tumors (CMT). In this work, the tumoral TGFβ expression was assessed by immuno
Externí odkaz:
https://doaj.org/article/9dcc46300afa4ae9b7d7aa1ea2ba25a5
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 7, Pp 561-566 (2024)
ObjectiveTo investigate the potential significance of FOXP3 expression in BRCA1/2-mutant breast cancer. MethodsA total of 48 BRCA mutation carriers (16 with BRCA1 and 32 with BRCA2) and 78 age-matched non-carriers were included in this study. Immunoh
Externí odkaz:
https://doaj.org/article/afc5471d38904448bc059fe915df2e14
Publikováno v:
Acta Medica Bulgarica, Vol 51, Iss 2, Pp 65-72 (2024)
Except the widely accepted use of immune Checkpoint inhibitors in the treatment of microsatellite instability-high (MSI-H) mismatch repair-deficient (MMRd) CRCs representing about 5% of all metastatic (m)CRC patients, new strategies are applied to cu
Externí odkaz:
https://doaj.org/article/dc3abf0054ba4379a494631c73280b34
Autor:
Dohnke, Sebastian, Moehser, Stephanie, Surnov, Alexey, Kurth, Thomas, Jessberger, Rolf, Kretschmer, Karsten, Garbe, Annette I.
In T cells, processes such as migration and immunological synapse formation are accompanied by the dynamic reorganization of the actin cytoskeleton, which has been suggested to be mediated by regulators of RhoGTPases and by F-actin bundlers. SWAP-70
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91929
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91929/attachment/ATT-0/
Autor:
Julius E. Chia, Robert P. Rousseau, Mumin Ozturk, Sibongiseni K. L. Poswayo, Rodney Lucas, Frank Brombacher, Suraj P. Parihar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionForkhead box P3 (Foxp3) T regulatory cells are critical for maintaining self-tolerance, immune homeostasis, and regulating the immune system.MethodsWe investigated interleukin-4 receptor alpha (IL-4Rα) signalling on T regulatory cells (T
Externí odkaz:
https://doaj.org/article/01834e39e29940b1a605b05bd814cedb
Autor:
Frank Ssedyabane, Nixon Niyonzima, Joseph Ngonzi, Josephine Nambi Najjuma, Hope Mudondo, Christopher Okeny, Doreen Nuwashaba, Deusdedit Tusubira
Publikováno v:
Gynecologic Oncology Reports, Vol 55, Iss , Pp 101466- (2024)
Biomarkers including Forkhead/winged-helix transcription factor box P3 have been proposed in immunohistochemical techniques to diagnose cervical lesions, but can be objectively quantified and measured in blood using methods that can be standardised.
Externí odkaz:
https://doaj.org/article/62ecd182b39e41d1bd4dde4106232496