Zobrazeno 1 - 7
of 7
pro vyhledávání: '"FOXO3A, Forkhead box O3a"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 491-506 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Wnt/β-catenin and phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin complex 1 (PI3K/AKT/mTORC1) pathways both are critically involved in colorectal cancer (CRC) development, although they are implicated in the modulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7a306ac692719a8347e0c547725351
http://www.sciencedirect.com/science/article/pii/S2352345X20300515
http://www.sciencedirect.com/science/article/pii/S2352345X20300515
Autor:
Johanna McChord, Katharina Ganss, Christian Krautz, Sebastian Hempel, Klaus-Peter Knoch, Michele Solimena, Robert Grützmann, Philippe Ravassard, Kamal Chowdhury, Jürgen Weitz, Stephan Kersting, Christian Pilarsky, Hassan Mziaut, Steffen Wolk, Georg Henniger
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 31, pp.150-162. ⟨10.1016/j.molmet.2019.11.012⟩
Molecular Metabolism, Vol 31, Iss, Pp 150-162 (2020)
Molecular Metabolism
Mol. Metab. 31, 150-162 (2020)
Molecular metabolism, Elsevier, 2020, 31, pp.150-162. ⟨10.1016/j.molmet.2019.11.012⟩
Molecular Metabolism, Vol 31, Iss, Pp 150-162 (2020)
Molecular Metabolism
Mol. Metab. 31, 150-162 (2020)
Objective MicroRNAs (miRNAs) play an integral role in maintaining beta cell function and identity. Deciphering their targets and precise role, however, remains challenging. In this study, we aimed to identify miRNAs and their downstream targets invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac233ce670f178447662777e657c669
https://doi.org/10.1016/j.molmet.2019.11.012
https://doi.org/10.1016/j.molmet.2019.11.012
Autor:
Ayako Makino, Ankit A. Desai, Ramon J. Ayon, Yali Gu, Ziyi Wang, Qian Zhang, Guofei Zhou, Shanshan Song, Franz Rischard, Jiwang Chen, Jason X.-J. Yuan, Kang Wu, Sujana Vinjamuri, Angela Balistrieri, Haiyang Tang, Rebecca Vanderpool, Joe G.N. Garcia, Jian Wang, Stephen M. Black
Publikováno v:
JACC. Basic to translational science, vol 3, iss 6
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 744-762 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 744-762 (2018)
Visual Abstract
Highlights • G protein-coupled receptors and tyrosine kinase receptors signal through the phosphoinositide 3-kinase/Akt/mTOR pathway to induce cell proliferation, survival, and growth. mTOR is a kinase present in 2 functionally
Highlights • G protein-coupled receptors and tyrosine kinase receptors signal through the phosphoinositide 3-kinase/Akt/mTOR pathway to induce cell proliferation, survival, and growth. mTOR is a kinase present in 2 functionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1d147fc74d88a884f1e521e7ef3c53
https://doi.org/10.1016/j.jacbts.2018.08.009
https://doi.org/10.1016/j.jacbts.2018.08.009
Autor:
Chuan Han Jonathan Foo, Shazib Pervaiz
Publikováno v:
Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology
Redox Biology
RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11cd3c78529b5f4eae7369f41a3e411
http://www.sciencedirect.com/science/article/pii/S2213231718311558
http://www.sciencedirect.com/science/article/pii/S2213231718311558
Autor:
Xunan Song, Yukun Zhang, Yiting Liu, Jingjing Liu, Hui Peng, Peng Lu, Xinru Sun, Yuelin Zhang, Zhidong Liu, Ebuka Olisaemeka Nwafor, Jiawei Li, Huan Qin
Publikováno v:
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111072-(2021)
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111072-(2021)
Graphical abstract
Highlights • Pathogenesis and characteristics of idiopathic pulmonary fibrosis (IPF) are presented. • The history and current situation of traditional Chinese medicine (TCM) in treating lung diseases are introduced. • Th
Highlights • Pathogenesis and characteristics of idiopathic pulmonary fibrosis (IPF) are presented. • The history and current situation of traditional Chinese medicine (TCM) in treating lung diseases are introduced. • Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1cd78c2f697ee7481eb77912ecf84f
https://doi.org/10.1016/j.biopha.2020.111072
https://doi.org/10.1016/j.biopha.2020.111072
Autor:
Bo Kong, Wen-Xing Ding, Grace L. Guo, Sharon Manley, Jessica A. Williams, Hong-Min Ni, Luciano DiTacchio
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 991-1002 (2014)
Redox Biology
Redox Biology
Alcoholic liver disease encompasses a wide spectrum of pathogenesis including steatosis, fibrosis, cirrhosis, and alcoholic steatohepatitis. Autophagy is a lysosomal degradation process that degrades cellular proteins and damaged/excess organelles, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eadef8f4ec7dcc850a037ebab00cfe1
https://doi.org/10.1016/j.redox.2014.08.007
https://doi.org/10.1016/j.redox.2014.08.007
Autor:
Tang H; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wu K; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wang J; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Vinjamuri S; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Gu Y; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Song S; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Wang Z; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Zhang Q; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona., Balistrieri A; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Ayon RJ; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Rischard F; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Vanderpool R; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Chen J; Department of Pediatrics, University of Illinois College of Medicine, Chicago, Illinois., Zhou G; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Department of Pediatrics, University of Illinois College of Medicine, Chicago, Illinois., Desai AA; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Division of Cardiology, Department of Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Black SM; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona., Garcia JGN; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona.; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The University of Arizona College of Medicine, Tucson, Arizona., Yuan JX; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona., Makino A; Division of Translational and Regenerative Medicine, The University of Arizona College of Medicine, Tucson, Arizona.; Department of Physiology, The University of Arizona College of Medicine, Tucson, Arizona.
Publikováno v:
JACC. Basic to translational science [JACC Basic Transl Sci] 2018 Dec 31; Vol. 3 (6), pp. 744-762. Date of Electronic Publication: 2018 Dec 31 (Print Publication: 2018).