Zobrazeno 1 - 10
of 609
pro vyhledávání: '"FOXO3A, Forkhead box O3a"'
Publikováno v:
PLoS ONE. Apr2013, Vol. 8 Issue 4, p1-16. 16p.
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61017 (2013)
Idiopathic Pulmonary Fibrosis is a lethal fibrotic disease characterized by the unrelenting proliferation and persistence of fibroblasts in a type I collagen-rich matrix that result in an expanding reticular network of fibrotic tissue. However, the u
Externí odkaz:
https://doaj.org/article/82b7b17e6bc041ba9395f315f88ec1f4
Autor:
O Bernard
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Review on FOXO3A (forkhead box O3A), with data on DNA, on the protein encoded, and where the gene is implicated.
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 491-506 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Wnt/β-catenin and phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin complex 1 (PI3K/AKT/mTORC1) pathways both are critically involved in colorectal cancer (CRC) development, although they are implicated in the modulation o
Autor:
Johanna McChord, Katharina Ganss, Christian Krautz, Sebastian Hempel, Klaus-Peter Knoch, Michele Solimena, Robert Grützmann, Philippe Ravassard, Kamal Chowdhury, Jürgen Weitz, Stephan Kersting, Christian Pilarsky, Hassan Mziaut, Steffen Wolk, Georg Henniger
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 31, pp.150-162. ⟨10.1016/j.molmet.2019.11.012⟩
Molecular Metabolism, Vol 31, Iss, Pp 150-162 (2020)
Molecular Metabolism
Mol. Metab. 31, 150-162 (2020)
Molecular metabolism, Elsevier, 2020, 31, pp.150-162. ⟨10.1016/j.molmet.2019.11.012⟩
Molecular Metabolism, Vol 31, Iss, Pp 150-162 (2020)
Molecular Metabolism
Mol. Metab. 31, 150-162 (2020)
Objective MicroRNAs (miRNAs) play an integral role in maintaining beta cell function and identity. Deciphering their targets and precise role, however, remains challenging. In this study, we aimed to identify miRNAs and their downstream targets invol
Autor:
Ayako Makino, Ankit A. Desai, Ramon J. Ayon, Yali Gu, Ziyi Wang, Qian Zhang, Guofei Zhou, Shanshan Song, Franz Rischard, Jiwang Chen, Jason X.-J. Yuan, Kang Wu, Sujana Vinjamuri, Angela Balistrieri, Haiyang Tang, Rebecca Vanderpool, Joe G.N. Garcia, Jian Wang, Stephen M. Black
Publikováno v:
JACC. Basic to translational science, vol 3, iss 6
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 744-762 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 744-762 (2018)
Visual Abstract
Highlights • G protein-coupled receptors and tyrosine kinase receptors signal through the phosphoinositide 3-kinase/Akt/mTOR pathway to induce cell proliferation, survival, and growth. mTOR is a kinase present in 2 functionally
Highlights • G protein-coupled receptors and tyrosine kinase receptors signal through the phosphoinositide 3-kinase/Akt/mTOR pathway to induce cell proliferation, survival, and growth. mTOR is a kinase present in 2 functionally
Autor:
Chuan Han Jonathan Foo, Shazib Pervaiz
Publikováno v:
Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biology
Redox Biology
RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct
Autor:
Xunan Song, Yukun Zhang, Yiting Liu, Jingjing Liu, Hui Peng, Peng Lu, Xinru Sun, Yuelin Zhang, Zhidong Liu, Ebuka Olisaemeka Nwafor, Jiawei Li, Huan Qin
Publikováno v:
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111072-(2021)
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111072-(2021)
Graphical abstract
Highlights • Pathogenesis and characteristics of idiopathic pulmonary fibrosis (IPF) are presented. • The history and current situation of traditional Chinese medicine (TCM) in treating lung diseases are introduced. • Th
Highlights • Pathogenesis and characteristics of idiopathic pulmonary fibrosis (IPF) are presented. • The history and current situation of traditional Chinese medicine (TCM) in treating lung diseases are introduced. • Th
Autor:
Bo Kong, Wen-Xing Ding, Grace L. Guo, Sharon Manley, Jessica A. Williams, Hong-Min Ni, Luciano DiTacchio
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 991-1002 (2014)
Redox Biology
Redox Biology
Alcoholic liver disease encompasses a wide spectrum of pathogenesis including steatosis, fibrosis, cirrhosis, and alcoholic steatohepatitis. Autophagy is a lysosomal degradation process that degrades cellular proteins and damaged/excess organelles, a
Autor:
Núñez, Ayla Kyler1 (AUTHOR), Arenas-Gómez, Claudia Marcela2 (AUTHOR) clarenasg@unal.edu.co, Carbonell Medina, Belfran Alcides1 (AUTHOR) clarenasg@unal.edu.co
Publikováno v:
International Journal of Translational Medicine. Dec2024, Vol. 4 Issue 4, p687-709. 23p.