Zobrazeno 1 - 10
of 32
pro vyhledávání: '"FOXO1, Forkhead box O1"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Anthracycline antineoplastic agents such as doxorubicin are widely used and highly effective component of adjuvant chemotherapy for breast cancer and curative regimens for lymphomas, leukemias, and sarcomas. The primary dose-limiting adverse effect o
Externí odkaz:
https://doaj.org/article/f36fc51c81094f26938a926dc050121a
Autor:
Niani Tiaye Bailey, Bilon Khambu, Gang Liu, Sophia Blessinger, Katherine Byrnes, Russell Scaife
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 33-49 (2022)
Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58c0ac6db641c550d04c5a5c6ba5a1a
https://doi.org/10.1016/j.apsb.2021.07.021
https://doi.org/10.1016/j.apsb.2021.07.021
Autor:
Takuya Kajimura, Isao Tamura, Yumiko Doi-Tanaka, Hiroshi Tamura, Yumiko Mihara, Norihiro Sugino, Ryo Maekawa, Shun Sato, Toshiaki Taketani, Yuichiro Shirafuta, Taishi Fujimura, Haruka Takagi
Publikováno v:
The Journal of Biological Chemistry
Human endometrial stromal cells (ESCs) differentiate into decidual cells by the action of progesterone, which is essential for implantation and maintenance of pregnancy. We previously reported that glucose uptake by human ESCs increases during decidu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a89913083a9b85db78acbd86a2eb6c
https://pubmed.ncbi.nlm.nih.gov/34478711
https://pubmed.ncbi.nlm.nih.gov/34478711
Autor:
Anja Jaeschke, David Y. Hui, Anton J.M. Roebroek, April Haller, Christopher Nam, Emily Igel, James G. Cash
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100012-(2021)
Journal of Lipid Research
Journal of Lipid Research
The LDL receptor-related protein-1 (LRP1) is highly expressed in numerous cell types, and its impairment is associated with obesity, diabetes, and fatty liver disease. However, the mechanisms linking LRP1 to metabolic disease are not completely under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c290f4d72cef781f80ddd5245699b83
https://lirias.kuleuven.be/handle/20.500.12942/704812
https://lirias.kuleuven.be/handle/20.500.12942/704812
Publikováno v:
Pharmacological Research
Graphical abstract Molecular targets modulated by artemisinins in respiratory diseases.
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the herb Artemisia annua. It has been used for centuries for the treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b9b3d7b7767e97cb84ac3227c7da4
Autor:
Masoumeh Tavakoli-Yaraki, Vahid Salimi, Mostafa Ibrahimi, Zahra Rampisheh, Mehrdad Bahrabadi, Pegah Babaheidarian, Ameinh Hosseini, Fatemeh Hosami, Alireza Mirzaei, Zohreh Abdolvahabi, Khodamorad Jamshidi, Soudabeh Fallah, Narges Khademian
Publikováno v:
Journal of Bone Oncology, Vol 23, Iss, Pp 100300-(2020)
Journal of Bone Oncology
Journal of Bone Oncology
Highlights • The SOX9 expression increased in tumor tissues and peripheral blood of malignant and benign bone tumors. • The protein level of SOX9 is enhanced in malignant bone tumor tissues. • SOX9 over-expression correlated with tumor severity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81383c3f75a7f37062761a0cf54f0a7
http://www.sciencedirect.com/science/article/pii/S2212137420300555
http://www.sciencedirect.com/science/article/pii/S2212137420300555
Autor:
Yangyang Hu, Ting Yuan, Huan Chen, Ting Yang, Jing Wang, Hong Yu, Qing Yuan, Danli Fu, Xiang Xie, Wenfeng Xu
Publikováno v:
Redox Biology
Redox Biology, Vol 20, Iss, Pp 247-260 (2019)
Redox Biology, Vol 20, Iss, Pp 247-260 (2019)
Oxidative stress and inflammation interact in the development of diabetic atherosclerosis. Intracellular hyperglycemia promotes production of mitochondrial reactive oxygen species (ROS), increased formation of intracellular advanced glycation end-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9eba5d1c8ff637dfcb1b8003cebc6f
https://doi.org/10.1016/j.redox.2018.09.025
https://doi.org/10.1016/j.redox.2018.09.025
Autor:
Paul, Debasish, Bargale, Anil Bapu, Rapole, Srikanth, Shetty, Praveen Kumar, Santra, Manas Kumar
Publikováno v:
Neoplasia (New York, N.Y.)
Protein phosphatases play a crucial role in cell cycle progression, cell survival, cellular signaling, and genomic integrity. The protein phosphatase 1 (PP1) regulatory subunit SDS22 plays a significant role in cell cycle progression. A recent study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b891d93bddfb4a69fff82d29bb6cf4ff
http://europepmc.org/articles/PMC6262785
http://europepmc.org/articles/PMC6262785
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 885-886 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is becoming a severe liver disorder worldwide. Autophagy plays a critical role in liver steatosis. However, the role of autophagy in NAFLD remains exclusive and under debate. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1287515fb220d00a7c882d49e29bf5ca
http://www.sciencedirect.com/science/article/pii/S2352345X20301922
http://www.sciencedirect.com/science/article/pii/S2352345X20301922
Autor:
Jing Gao, Takahito Otani, Masato Hirata, Satoru Mukai, Tomoyo Kawakubo-Yasukochi, Ronghao Tang, Akiko Mizokami, Sakura Chishaki, Hiroshi Takeuchi, Eijiro Jimi, Takashi Kanematsu, Tomomi Sano, Miho Matsuda
Publikováno v:
The Journal of Biological Chemistry
The G protein-coupled receptor GPRC6A regulates various physiological processes in response to its interaction with multiple ligands, such as extracellular basic amino acids, divalent cations, testosterone, and the uncarboxylated form of osteocalcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1071bba384b52dd2c1bcbfadb6f1ee23
https://pubmed.ncbi.nlm.nih.gov/33428938
https://pubmed.ncbi.nlm.nih.gov/33428938