Zobrazeno 1 - 10
of 405
pro vyhledávání: '"FOUNDER POPULATION"'
Autor:
Megan T. Lynch, Kristin A. Maloney, Huichun Xu, James A. Perry, Regeneron Genetics Center, Alan R. Shuldiner, Braxton D. Mitchell
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background: Autozygosity, the proportion of the genome that is homozygous by descent, has been associated with variation in multiple health-related traits impacting evolutionary fitness. Autozygosity (FROH) is typically measured from runs of
Externí odkaz:
https://doaj.org/article/6bf9374a95e0483db170da89ad992e08
Akademický článek
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Autor:
Philippe Pierre Robichaud, Eric P. Allain, Sarah Belbraouet, Claude Bhérer, Jean Mamelona, Jason Harquail, Stéphanie Crapoulet, Nicolas Crapoulet, Mathieu Bélanger, Mouna Ben Amor
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background Founder populations that have recently undergone important genetic bottlenecks such as French-Canadians and Ashkenazi Jews can harbor some pathogenic variants at a higher carrier rate than the general population, putting them at a
Externí odkaz:
https://doaj.org/article/d3ae837d67ef4302a689bd21bc68ae3f
Akademický článek
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Akademický článek
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Autor:
Anel Mahmutovic, Aaron Nicholas Gillman, Silje Lauksund, Natasha-Anne Robson Moe, Aime Manzi, Merete Storflor, Pia Abel zur Wiesch, Sören Abel
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1035-1051 (2021)
Microbial division rates determine the speed of mutation accumulation and thus the emergence of antimicrobial resistance. Microbial death rates are affected by antibiotic action and the immune system. Therefore, measuring these rates has advanced our
Externí odkaz:
https://doaj.org/article/4d975169c28e4ac99a446990b4a3acbb
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT During infection, the rates of pathogen replication, death, and migration affect disease progression, dissemination, transmission, and resistance evolution. Here, we follow the population dynamics of Vibrio cholerae in a mouse model by label
Externí odkaz:
https://doaj.org/article/7ac5a0dd437a4c22aa1ae2aabdc7aa05
Autor:
Nikolay I. Markov, Maryana N. Ranyuk, Elmar A. Babaev, Ivan V. Seryodkin, Alexander V. Senchik, Elena A. Bykova, Alexander V. Esipov, Sabir T. Nurtazin, Olga S. Pavlova, Vera A. Matrosova
Publikováno v:
Diversity, Vol 14, Iss 11, p 916 (2022)
Translocations and introductions are important events that allow organisms to overcome natural barriers. The genetic background of colonization success and genetic consequences of the establishment of populations in new environments are of great inte
Externí odkaz:
https://doaj.org/article/ab5d676aac1c49f995d90b50f924e4d4
Autor:
Daehler, Curtis C.
Publikováno v:
American Journal of Botany, 1999 Jan 01. 86(1), 131-139.
Externí odkaz:
https://www.jstor.org/stable/2656962
Autor:
Konstantinos Mitropoulos, Eleni Merkouri Papadima, Georgia Xiromerisiou, Angeliki Balasopoulou, Kyriaki Charalampidou, Vasiliki Galani, Krystallia-Vassiliki Zafeiri, Efthymios Dardiotis, Styliani Ralli, Georgia Deretzi, Anne John, Kyriaki Kydonopoulou, Elpida Papadopoulou, Alba di Pardo, Fulya Akcimen, Annalisa Loizedda, Valerija Dobričić, Ivana Novaković, Vladimir S. Kostić, Clint Mizzi, Brock A. Peters, Nazli Basak, Sandro Orrù, Evangelos Kiskinis, David N. Cooper, Spyridon Gerou, Radoje Drmanac, Marina Bartsakoulia, Evangelia-Eirini Tsermpini, Georgios M. Hadjigeorgiou, Bassam R. Ali, Theodora Katsila, George P. Patrinos
Publikováno v:
Human Genomics, Vol 11, Iss 1, Pp 1-10 (2017)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a devastating disease whose complex pathology has been associated with a strong genetic component in the context of both familial and sporadic disease. Herein, we adopted a next-generation se
Externí odkaz:
https://doaj.org/article/56ac508e4f8647e88e5a5eebcc04cdbd